Histological verification of non-specific aorta-arteritis (Takayasu's arteritis) using percutaneous transluminal atherectomy.

Diagnosis of non-specific aorto-arteritis (NSAA, Takaysu's arteritis) is typically based on clinical and investigational parameters. We report here about two patients with clinically suspected diagnosis of a Takayasu's arteritis already under anti-inflammatory therapy in whom percutaneous transluminal atherectomy of subclavian and axillary artery stenoses was performed to relief the patients from symptoms--intermittent dyspraxia of the arms--and to verify the clinical diagnosis by histology. In the first case aorto-arteritis could be histologically confirmed through the analysis of plaque material including media structures excised from the subclavian and axillary arteries using a new device for atherectomy. The biopsy showed diffuse inflammation and granulomatous lesions with giant cells typically for Takayasu's disease. In the second patient, biopsy showed no acute or chronic inflammatory signs but only atherosclerotic lesions. Percutaneous transluminal atherectomy is therefore not only an interventional but also a diagnostic tool and should be used in every case of interventional therapy of suspected aorto-arteritis to make the clinical diagnosis and as a major consequence the initiation of an aggressive anti-inflammatory medical therapy more reliable.

[Motility of spermatozoa in the cervical mucus of copper wire I.U.D. users]. / La motilite des spermatozoides dans le mucus cervical chez les proteuses de D.I.U. au cuivre.

PIP: Penetration, progression, and survival tests of spermatozoa were studied in vitro in the cervical mucus of 18 wearers of copper IUD, and in the cervical mucus of 10 control women. The penetration test in IUD wearers was inferior to that of the controls, and the progression test, and the density of penetration tests revealed greater mobility in the controls' mucus than in that of IUD wearers. The test of toxicity of ion copper simply revealed, in both groups, a reduction in the mobility of spermatozoa. The cervical score was, over all, inferior in IUD wearers than in controls.^ieng