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1.
Zootaxa ; 5397(3): 435-443, 2024 Jan 05.
Artigo em Inglês | MEDLINE | ID: mdl-38221193

RESUMO

A new species of Scirtothrips is described from India, S. donumdei, collected on leaves of Senegalia pennata (Fabaceae). Partial mitochondrial cytochrome c oxidase subunit 1 (mtCOI) gene sequence of the species was sequenced and the annotated sequence was submitted to NCBI GenBank.


Assuntos
Fabaceae , Tisanópteros , Animais , Tisanópteros/genética , Índia , Folhas de Planta , Mitocôndrias
2.
Zootaxa ; 5319(4): 589-594, 2023 Jul 27.
Artigo em Inglês | MEDLINE | ID: mdl-37518209

RESUMO

A remarkable new species, Hydatothrips longirostris, with an elongate mouth cone extending to the metasternum is described from India. Dendrothrips glynn Mound, a dendrothripine species, is newly recorded from India.

3.
Cureus ; 15(2): e34542, 2023 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-36879706

RESUMO

Background The anterior cruciate ligament (ACL) reconstruction is a standard surgery in patients with instability of the knee caused by ACL insufficiency. Several differential procedures using grafts and implants such as loops, buttons, and screws have been described. This study aimed to assess the functional outcomes of ACL reconstruction surgery using titanium adjustable loop buttons and poly-L-co-DL-lactic acid-beta tricalcium phosphate (PLDLA-bTCP) interference screws. Methodology This was a retrospective, observational, single-center, and clinical study. A total of 42 patients who underwent ACL reconstruction at a tertiary trauma center in northern India between 2018 and 2022 were recruited. Data including demographics, details of the injury, surgery, implants, and surgical outcomes were collected from the patients' medical records. Further, post-surgery details such as re-injury, adverse events, International Knee Documentation Committee (IKDC) profiles, and Lysholm knee score were recorded from the enrolled patients through a telephonic follow-up. Pain score and Tegner activity scale were used to compare the knee status before and after surgery. Results At the time of surgery, the mean age of the recruited patients was 31.1 ± 8.8 years, with a male preponderance of 93%. About 57% of patients had left knee injuries. The common symptoms were instability (67%), pain (62%), swelling (14%), and giving away (5%). During surgery, titanium adjustable loop button and PLDLA-bTCP interference screw implants were used in all patients. The mean follow-up time was 21.2 ± 14.2 months. Based on patient responses, the mean IKDC and Lysholm scores were found to be 54.02 ± 5.93 and 94.4 ± 4.73, respectively. Further, the proportion of patients reporting pain decreased from 62% before surgery to 21% after surgery. The mean Tegner score revealed a significant increase in the activity levels of the patients post-surgery compared to pre-surgery (p < 0.05). Lastly, no adverse events or re-injuries were reported in any of the patients during follow-up. Conclusions Our findings revealed a significant improvement in Tegner activity levels and pain scores after surgery. In addition, patient-reported IKDC and Lysholm scores fell under the category of good knee status and function, suggesting a satisfactory functional outcome of ACL reconstruction. Hence, titanium adjustable loop and PLDLA-bTCP interference screws may be a good choice of implants for successful ACL reconstruction surgery.

4.
Zootaxa ; 5169(2): 177-182, 2022 Jul 28.
Artigo em Inglês | MEDLINE | ID: mdl-36101244

RESUMO

A new species of Hydatothrips is described from India, H. initium. A key to the ten species of Hydatothrips recorded from India is also provided.


Assuntos
Tisanópteros/classificação , Animais , Índia
5.
Zootaxa ; 5209(3): 365-372, 2022 Nov 17.
Artigo em Inglês | MEDLINE | ID: mdl-37045386

RESUMO

Pseudodendrothrips umbrolateralis sp. n. is described from India. An identification key to the seven Pseudodendrothrips species recorded from India is provided. The earlier record from India of P. bhattii Kudo is considered a misidentification of P. darci (Girault) and hence, is removed from the fauna of India.


Assuntos
Tisanópteros , Animais , Distribuição Animal , Índia
6.
Bioorg Med Chem Lett ; 15(24): 5478-82, 2005 Dec 15.
Artigo em Inglês | MEDLINE | ID: mdl-16216508

RESUMO

A 3D quantitative structure-activity relationship study for inhibition of calcium-sensing receptor in the aryloxypropanolamine series predicted that these molecules adopt a U-shaped conformation with pi-stacking between the two aromatic rings. This hypothesis led to the discovery of novel 1-arylmethyl pyrrolidin-2-yl ethanol amines capable of antagonizing the calcium-sensing receptor with potency comparable to that of NPS-2143.


Assuntos
Receptores de Detecção de Cálcio/antagonistas & inibidores , Etanolaminas/síntese química , Etanolaminas/química , Etanolaminas/farmacologia , Humanos , Modelos Moleculares , Conformação Molecular , Osteoporose/tratamento farmacológico , Conformação Proteica , Pirrolidinas/síntese química , Pirrolidinas/química , Pirrolidinas/farmacologia , Receptores de Detecção de Cálcio/química , Relação Estrutura-Atividade
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