Radiographic comparison of density and height of posterior maxillary bone after open sinus lift surgery with and without PRF.

Background: Expansion of maxillary sinus towards the alveolar crest due to tooth loss or horizontal‒vertical resorption of the alveolar bone decreases the available bone for the placement of dental implants in the posterior maxilla. The method suggested for placing implants with a standard length is the use of sinus lift surgery with autogenous bone graft or bone substitute materials. The aim of the present research, with split-mouth design, was radiographic comparison of the density and height of the posterior of maxillary bone after open sinus lift procedure with and without PRF. Materials and Methods: In this split-mouth clinical trial, 14 patients were evaluated, with complete or partial bilateral edentulism of the upper jaw. In each case, for the sinus lift surgery of the test side, PRF was used, while in the sinus lift surgery of the other side of the same patient no graft materials were used. After six months and before the second surgery, CBCT was used to evaluate bone density and height. Results: All the 41 implants were osseointegrated and were clinically stable. The bone height was 1.42 mm higher in the PRF group than the group without PRF, which was statistically significant. The mean density of the bone formed around the dental implants in the PRF group was 52.85 units higher than that of the group without PRF, which was statistically significant. Conclusion: Using PRF in sinus lift surgery might enhance the quantity and quality of bone formation.

Clinical evaluation of the effect of acentric double pedicle graft with and without the use of platelet-rich fibrin (PRF) on root coverage outcomes in class I and II Miller root recessions: A randomized clinical trial.

Background: Acentric double pedicle graft is an alternative to double pedicle graft, which can improve clinical outcomes by removing tension in sutures. This study examined the effect of using platelet-rich fibrin (PRF) on the success rate of acentric double pedicle graft in treating patients with Miller Class I and II recessions. Methods: A total of 16 Miller Class I and II lesions were studied in 8 patients. The samples were divided into two groups in terms of PRF use: with PRF and without PRF. Indices, including recession depth, width of keratinized gingiva and pocket depth, were measured with a standard Michigan O probe with Williams marking. Six months later, Kolmogorov-Smirnov test and Wilcoxon nonparametric test were applied with SPSS17 to analyze data. Results: The recession depth, width of keratinized gingiva, and increased root coverage exhibited a significant difference between the two groups after surgery, but no significant difference was found in pocket depths. Conclusion: Applying PRF with acentric double pedicle graft reduced the recession depth, increased the width of keratinized gingiva and enhanced the extent of root coverage when compared with the situation where PRF was not used. Therefore, this study supports the use of PRF with acentric double pedicle graft in root coverage treatments.