Preparation and use of morphine capsules in paediatric patients with burns.

Morphine is an analgesic agent used for the symptomatic relief of moderate to severe pain. The lack of oral paediatric form of morphine hydrochloride has led the pharmacy unit to develop capsules containing 1 mg of morphine. These capsules are prepared in conformity with G.M.P. and controlled by H.P.L.C. 73 burn children were treated in this study with pain suppression without adverse effects. This galenic form may be an adequate candidate for the management of paediatric patients because of its analgesic qualities and of numerous advantages.

[Hypnotics and anxiolytics: nominal daily delivery and development of their consumption at North University Hospital Center of Marseille (1991-1994)]. / Hypnotiques et anxiolytiques: Mise en place de la D.N.J et évolution de leur consommation au sein de C.H.U Nord de Marseille (1991-1994).

For public health concerns, a nominal daily delivery of anxiolytic and hypnotic drugs has progressively been set up since March 1992 for the whole of the North University-Hospital Center (U.H.C) of Marseille. The purpose of this monitored prescription process is to limit their use, which seemed undue. After the first six month of implementation, drug use decreased significantly(-50%) and has since stabilized. This reduction is particularly pronounced for benzodiazepines and especially anxiolytic drugs. The decree of August 9, 1991 has enabled us to optimize the delivery of these drugs and thus improve prescription for more rational indications.