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1.
Sci Rep ; 9(1): 17854, 2019 11 28.
Artigo em Inglês | MEDLINE | ID: mdl-31780759

RESUMO

A revolution in functional brain imaging techniques is in progress in the field of neurosciences. Optical imaging techniques, such as high-density diffuse optical tomography (HD-DOT), in which source-detector pairs of probes are placed on subjects' heads, provide better portability than conventional functional magnetic resonance imaging (fMRI) equipment. However, these techniques remain costly and can only acquire images at up to a few measurements per square centimetre, even when multiple detector probes are employed. In this study, we demonstrate functional brain imaging using a compact and affordable setup that employs nanosecond-order pulsed ordinary laser diodes and a time-extracted image sensor with superimposition capture of scattered components. Our technique can simply and easily attain a high density of measurement points without requiring probes to be attached, and can directly capture two-dimensional functional brain images. We have demonstrated brain activity imaging using a phantom that mimics the optical properties of an adult human head, and with a human subject, have measured cognitive brain activation while the subject is solving simple arithmetical tasks.


Assuntos
Encéfalo/diagnóstico por imagem , Imagem Óptica/métodos , Humanos , Lasers , Imagem Óptica/instrumentação , Imagens de Fantasmas
2.
Appl Opt ; 54(24): 7316-22, 2015 Aug 20.
Artigo em Inglês | MEDLINE | ID: mdl-26368767

RESUMO

We propose a method for visualizing three-dimensional objects in scattering media. Our method is based on active illumination using three-dimensionally coded patterns and a numerical algorithm employing a sparsity constraint. We experimentally demonstrated the proposed imaging method for test charts located three-dimensionally at different depths in the space behind a translucent sheet.


Assuntos
Imageamento Tridimensional/métodos , Algoritmos , Artefatos , Simulação por Computador , Desenho de Equipamento , Interpretação de Imagem Assistida por Computador/métodos , Processamento de Imagem Assistida por Computador/métodos , Luz , Iluminação/métodos , Microscopia Confocal/métodos , Modelos Teóricos , Reconhecimento Automatizado de Padrão , Distribuição de Poisson , Espalhamento de Radiação
3.
Opt Express ; 23(26): 33902-10, 2015 Dec 28.
Artigo em Inglês | MEDLINE | ID: mdl-26832049

RESUMO

We experimentally demonstrated object recognition through scattering media based on direct machine learning of a number of speckle intensity images. In the experiments, speckle intensity images of amplitude or phase objects on a spatial light modulator between scattering plates were captured by a camera. We used the support vector machine for binary classification of the captured speckle intensity images of face and non-face data. The experimental results showed that speckles are sufficient for machine learning.

4.
Appl Opt ; 53(11): 2532-8, 2014 Apr 10.
Artigo em Inglês | MEDLINE | ID: mdl-24787427

RESUMO

We have developed a new method to analyze the amount and distribution of diffraction light for a diffraction grating lens. We have found that diffraction light includes each-order diffraction light and striped diffraction light. In this paper, we describe characteristics of striped diffraction light and suggest a way to analyze diffraction light. Our analysis method, which considers the structure of diffraction grating steps, can simulate the aberrations of an optical system, each-order diffraction light, and striped diffraction light simultaneously with high accuracy. A comparison between the simulation and experimental results is presented, and we also show how our analysis method can be used to optimize a diffraction grating lens with low flare light.

5.
Appl Opt ; 52(26): 6543-8, 2013 Sep 10.
Artigo em Inglês | MEDLINE | ID: mdl-24085131

RESUMO

The potential exists to apply diffraction gratings to optical imaging systems to improve camera resolution and shorten optical length. However, we have noted the generation of striped flare lights, which differ from unnecessary-order diffraction lights, under intense lighting. We have elucidated the generation principle of these new striped lights and have discovered that they are caused by narrow diffraction grating rings. In this paper, using an analysis based on Fraunhofer diffraction, we suggest a way of minimizing them by designing an appropriate phase function structure, and test the efficacy of this design using our own manufactured prototype.

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