RESUMO
The article contains the results of the test of PFK-M composition bactericidal activity against a range of extremely dangerous infective pathogens. The preparation proved to be highly effective for the disinfection of surfaces, sanitary and technical equipment, linen, dishes, and medical utensils contaminated by plague, cholera, and anthrax pathogens. The study found that the antimicrobial activity of the preparation increased after heating and lowered when the object to be disinfected was contaminated with protein admixtures. According to the results of the disinfectological expertise, the preparation was recommended for practical application.
Assuntos
Bacillus anthracis/efeitos dos fármacos , Desinfetantes/farmacologia , Desinfecção/métodos , Controle de Infecções/métodos , Vibrio cholerae/efeitos dos fármacos , Yersinia pestis/efeitos dos fármacos , Antraz/prevenção & controle , Bacillus anthracis/isolamento & purificação , Cólera/prevenção & controle , Combinação de Medicamentos , Humanos , Peste/prevenção & controle , Vibrio cholerae/isolamento & purificação , Yersinia pestis/isolamento & purificaçãoRESUMO
Changes in fine morphological structures of E. coli, S. aureus and spores of B. anthracis vaccine strain STI under the action of the disinfectant "Veltolen" manufactured by the Closed Joint-Stock Company "Velt", were evaluated. When used at concentrations of 0.0025-0.025%, the preparation induced the loosening of the cell wall in all microorganisms under study, the intensive formation of bubbles on the cell wall surface with their subsequent separation from the cell wall and the formation of "rosettes". In case of more prolonged exposure (up to 60 minutes) and higher concentrations of the preparation these phenomena became more intensive and finally led to the destruction of bacterial cells.