1.
RSC Adv
; 10(38): 22397-22416, 2020 Jun 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35514555
RESUMO
The preparation of a range of amino acid derived guanidine organocatalysts is reported together with their application to the Michael addition of 2-hydroxy-1,4-napthoquinone to ß-nitrostyrene, achieving a maximum ee of 56%. Some insight into the mechanism was sought by using X-ray crystallography and a detailed study of the intra- and intermolecular hydrogen bonding is reported.