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Papillomavirus Res ; 6: 22-26, 2018 12.
Artigo em Inglês | MEDLINE | ID: mdl-30244072

RESUMO

OBJECTIVE: This study was conducted to determine the prevalence and distribution of high-risk human papillomavirus (HR-HPV) genotypes among sexually active women in Tenkodogo, Burkina Faso. METHODS: Among 131 sexually active women attending the Tenkodogo Urban Medical Center, endocervical samples were collected prior to screening for precancerous lesions. After viral DNA extraction, fourteen HR-HPV genotypes were characterized by real-time multiplex PCR in these cervical samples. RESULTS: The mean age was 35.5 ±â€¯9.5 years. Of the 131 women, 45 were infected with at least one HR-HPV genotype. The prevalence of HR-HPV infection among these women was 34.4%. Among the 45 oncogenic HPV-infected women, single HR-HPV genotype was found in 55.6% while 44.4% were infected with more than one HR-HPV genotype. The most frequent genotypes were HPV56 (36.5%), HPV66 (36.5%). CONCLUSION: Tenkodogo women included in this study had a higher prevalence of HPV 56, HPV 66. A larger study with a more representative sample would therefore be needed to determine predominant oncogenic genotypes in the subregion and especially in cancer cases.


Assuntos
Genótipo , Papillomaviridae/classificação , Papillomaviridae/isolamento & purificação , Infecções por Papillomavirus/epidemiologia , Infecções por Papillomavirus/virologia , Adulto , Burkina Faso/epidemiologia , Colo do Útero/virologia , DNA Viral/genética , DNA Viral/isolamento & purificação , Feminino , Técnicas de Genotipagem , Humanos , Pessoa de Meia-Idade , Reação em Cadeia da Polimerase Multiplex , Papillomaviridae/genética , Prevalência , Reação em Cadeia da Polimerase em Tempo Real , Adulto Jovem
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