[Histiocytoid cardiomyopathy in an infant].

We present a description of a clinical observation of a histiocytoid cardiomyopathy in a female patient aged 4 months. This pathology is rare in pediatric cardiology. Its etiology is linked with mutation of the gene encoding mitochondrial cytochrome B (mitochondrial transport of electrons). This mutation leads to a specific morphological and functional abnormalities of cardiomyocytes. Purkinje cells and cells of conduction system at microscopy appear as histiocytolike foam cells cytoplasm of which contain large amount of lipids and glycogen. Girls prevail among those affected. The case reflects clinical picture characteristic for this nosology: malignant arrhythmia and cardiomegaly with fatal outcome.

[Meckel's diverticulum in children]. / Divertikul Mekkelia u detei.

In 1978-1988 operations were performed on 92 children: 35 with diverticulitis, 7 with intestinal intussusception, 5 with hemorrhage from an ulcer of the diverticulum, 13 with strangulation or mechanical ileus, 2 with strangulated Littre's hernia, one with torsion of the omentum, 22 with secondary diverticulitis, and in 7 children Meckel's diverticulum was a chance finding during other operations in the cavities. Boys accounted for 60.9' (56) of cases. There were 12 children under one year of age, nine from 1 to 3 years, 17 from 3 to 5 years, 17 from 5 to 7 years, and 12 children aged from 7 to 10 years. The clinical manifestations depended on the pathological changes developing in Meckel's diverticulum. A clinical picture of acute appendicitis developed in diverticulitis, six children had a typical picture of intussusception, and one child had a picture of acute abdomen. Anemia and a stool with dark blood were encountered in hemorrhage from a diverticular ulcer. Seven out of 13 children with ileus had a pronounced clinical picture, in the remaining 5 it was unclear and resembled that of acute appendicitis. Meckel's diverticulum was suspected before the operation in 17 (9.95%) patients. The Volkovich-Dyakonov laparotomy approach was used in 64 children, a pararectal incision in 9, a transrectal incision in 15, a median incision in one patient, hernio-laparotomy was conducted in one and Shpizi's operation in 2 children. Diverticulectomy was accomplished by the oblique-transverse method in 79 children, by the wedge techniques in 5, by the purse-string method in 2 patients, and resection of the intestine with the diverticulum was conducted in 5 children.(ABSTRACT TRUNCATED AT 250 WORDS)

[Morphology of tuberculous meningitis in children]. / O morfologii tuberkuleznogo meningita u detei.

25 observations of tuberculosis meningitis in children who died at the age from 3 months to 6 years with a clinical course from 5 days to 6.5 months were analyzed. Meningitis was not diagnosed clinically in 6 children. The inflammation was of an exudative or exudative-necrotic type at all periods of the disease. Specific features were: long-lasting macrophagal reaction, the presence of numerous plasma-cells (particularly at late stages of the disease), predominance of diffuse rather than granulomatous inflammation. Combination of delayed and immediate hypersensitivity reactions and possible organ specificity of the process may be involved in the pathogenesis of the disease.

[Complications and outcome of conservative and surgical treatment of intestinal invagination in children]. / Oslozhneniia i iskhody konservativnogo i operativnogo lecheniia invaginatsii kishechnika u detei.

The authors treated for intestinal invagination 726 children: conservatively--528, surgically--198. In conservative treatment, 0.96% of the patients developed complications, there were no lethal outcomes. After the operation, the complications were noted in 19.69% of the children, who were mainly operated 2 days after onset of the disease and later.