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J Child Neurol ; 30(10): 1362-5, 2015 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-25387546

RESUMO

Chorea may be secondary to hyperosmolar nonketotic hyperglycemia, but such situation has rarely been described in adolescents, particularly as the initial and single manifestation of type 1 diabetes. We describe a case of a previously healthy 14-year-old girl with sudden onset of choreic movements on her left upper and lower limbs. Brain computed tomography (CT) and magnetic resonance imaging (MRI) revealed an area of hyperdensity/hyperintensity affecting the right striatum. Blood glucose was 349 mg/dL. Despite adequate glucose control, the involuntary movements persisted and haloperidol, later substituted with valproate, was prescribed, with satisfactory but not complete resolution of the chorea. In 2 other occasions, when the patient had an infection and subsequent hyperglycemia, the chorea relapsed. Although not common, hyperglycemia must be considered in the differential diagnosis of acute hemichorea-hemiballismus in children and adolescents, particularly because it is a potentially reversible cause.


Assuntos
Coreia/fisiopatologia , Diabetes Mellitus Tipo 1/fisiopatologia , Discinesias/fisiopatologia , Adolescente , Antibacterianos/efeitos adversos , Antibacterianos/uso terapêutico , Encéfalo/patologia , Coreia/diagnóstico , Coreia/tratamento farmacológico , Coreia/patologia , Diabetes Mellitus Tipo 1/diagnóstico , Diabetes Mellitus Tipo 1/tratamento farmacológico , Diabetes Mellitus Tipo 1/patologia , Diagnóstico Diferencial , Discinesias/diagnóstico , Discinesias/tratamento farmacológico , Discinesias/patologia , Feminino , Infecção Focal/tratamento farmacológico , Infecção Focal/fisiopatologia , Humanos , Imageamento por Ressonância Magnética , Doenças da Unha/tratamento farmacológico , Doenças da Unha/fisiopatologia , Recidiva , Tomografia Computadorizada por Raios X
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