RESUMO
Introducción: Las personas con fibromialgia refieren una notable interferencia de la enfermedad en su calidad de vida. A pesar de que los síntomas de la fibromialgia suelen seguir un curso crónico, la calidad de vida de las pacientes puede mejorar. Por consiguiente, la mejoría de la calidad de vida debería ser un objetivo terapéutico prioritario. El objetivo de este estudio longitudinal fue evaluar los determinantes de la calidad de vida en las pacientes con fibromialgia seis meses después de haber recibido un tratamiento multidisciplinario. Método: En 40 pacientes seleccionadas consecutivamente se analizaron las variables previamente descritas como sólidos determinantes de la calidad de vida antes y seis meses después de realizar un tratamiento multidisciplinario. Se realizó un análisis de componentes principales del cambio observado en cada uno de estos determinantes y se analizó su relación con la mejoría de la calidad de vida mediante análisis de regresión multivariante. Resultados: El análisis de los componentes principales observó 7 factores independientes que explicaron el 76.4% de la varianza entre sujetos del cambio en las variables clínicas evaluadas. Los análisis de regresión multivariantes mostraron que la mejoría en las distintas facetas de la calidad de vida dependió principalmente de las creencias favorables a la posibilidad de disminuir el dolor mediante recursos propios y de un afrontamiento activo que conllevara un incremento de la capacidad funcional subjetiva.Conclusiones: Dada la cronicidad de los síntomas de la fibromialgia, la mejoría de la calidad de vida de las pacientes debería basarse en la promoción de las creencias de control del dolor y el incremento de la autoeficacia teniendo, no obstante, en cuenta el efecto a la vez negativo y positivo de la ayuda externa.(AU)
Introduction: People with fibromyalgia report a significant interference of the disease in their quality of life. Although the symptoms of fibromyalgia usually follow a chronic course, the quality of life of patients can improve. Therefore, improving quality of life should be a priority therapeutic goal. The objective of this longitudinal study was to assess the determinants of quality of life in patients with fibromyalgia six months after receiving multidisciplinary treatment. Method: In 40 consecutively selected patients, the variables previously described as solid determinants of quality of life were analyzed before and six months after receiving a multidisciplinary treatment. A principal component analysis of the change observed in each of these determinants was performed and their relationship with improvement in quality of life was analyzed using multivariate regression analysis. Results: Principal component analysis of change found 7 independent factors that explained 76.4% of the between-subject variance of change in clinical variables assessed. The multivariate regression analysis showed that the improvement in the different facets of quality of life depended mainly on the promotion of perceived ability to control pain through ones own resources and on active coping that would lead to an increase in subjective functional capacity. Conclusions: Given the chronicity of fibromyalgia symptoms, improvement of patients quality of life should be based on the promotion of pain control beliefs and the increase of self-efficacy considering, however, the effect both negative and positive of significant others assistance.(AU)
Assuntos
Humanos , Masculino , Feminino , Pré-Escolar , Criança , Adolescente , Qualidade de Vida , Fibromialgia , Terapêutica , Autoeficácia , Controle Interno-Externo , Estudos Longitudinais , DorRESUMO
This study evaluated the accuracy of the Wirele-X (Forum Tec, Ashkelon, Israel), a novel Bluetooth-enabled wireless electronic apex locator. Thirty-one extracted teeth with mature apices were used. Under 10X magnification, the actual canal lengths were determined. The teeth were embedded in alginate and electronic canal lengths were obtained using the Root ZX II and Wirele-X electronic apex locators. The actual canal lengths and electronic canal lengths were compared with Student's t-test. The average distance from the file tip to the actual canal length was -0.11 mm (±0.16) for the Root ZX II, and - 0.07 mm (±0.21) for the Wirele-X. There were no statistically significant differences between the two electronic apex locators in their ability to determine the actual canal length (p > 0.05). The wireless apex locator (Wirele-X) and the wired apex locator (Root ZX II) were found to be equally accurate.
Assuntos
Cavidade Pulpar , Ápice Dentário , Humanos , Odontometria , Raiz Dentária , Eletrônica , Preparo de Canal RadicularRESUMO
OBJECTIVES: To determine the prevalence and characteristics of post-COVID-19 (PC) in fibromyalgia (FM) patients. METHODS: Retrospective, multi-centric, observational study, comparing a group of FM patients (FM group) with another group of patients with other rheumatic diseases (RD group). COVID-19 diagnosis was established by positive polymerase chain reaction or antigen during acute infection or by positive antibodies thereafter. We considered PC diagnosis when symptoms remain after COVID-19. We collected the principal characteristics of COVID-19, the severity of fatigue, waking unrefreshed and cognitive impairment, and persistent symptoms. The American College of Rheumatology (ACR) criteria and the Combined Index of Severity in Fibromyalgia (ICAF) were collected in the FM group. RESULTS: RD group (n = 56) had more pneumonia (p = 0.001) and hospital admissions (p = 0.002), but the FM group (n = 78) had a higher number of symptoms (p = 0.002). The percentage of patients with PC was similar between groups (FM group 79.5%; RD group 66.1%, p = 0.081). FM group had more PC symptoms (p = 0.001), more impairment after COVID-19 (p = 0.002) and higher severity of fatigue, waking unrefreshed and cognitive impairment (p < 0.0001). Only loss of smell was more frequent in the FM group (p = 0.005). The FM group with PC (n = 29) showed more severity of the Combined Index of Severity in Fibromyalgia (ICAF) total score and physical factor after COVID-19, while emotional, coping factors and the ACR criteria did not change. CONCLUSIONS: The prevalence of PC in FM patients is similar to RD patients. In FM patients, the presence of PC does not appear to impact the severity of FM.
Assuntos
Doenças Autoimunes , COVID-19 , Fibromialgia , Doenças Reumáticas , COVID-19/epidemiologia , Teste para COVID-19 , Fadiga/diagnóstico , Fadiga/epidemiologia , Fibromialgia/diagnóstico , Fibromialgia/epidemiologia , Fibromialgia/psicologia , Humanos , Prevalência , Estudos Retrospectivos , Doenças Reumáticas/diagnóstico , Doenças Reumáticas/epidemiologia , Índice de Gravidade de Doença , Inquéritos e QuestionáriosRESUMO
OBJECTIVES: To the scarce information on dietary habits in fibromyalgia (FM), it is added that there are no comparative studies with other rheumatic diseases. The objective of this study was to characterise the dietary habits of patients with FM by comparing, for the first time, with healthy controls (HC) and rheumatoid arthritis (RA). METHODS: This cross-sectional, observational study was based on data obtained from the Dietfibrom project for FM and from the IMID Consortium for RA and HC. All participants completed a food frequency questionnaire evaluating their weekly dietary intake of main food groups. The three cohorts were compared using a multiple logistic regression model adjusted for age, sex, and body mass index. RESULTS: After quality control, n=287 FM, n=1,983 HC and n=1,942 RA patients were analysed. We found that FM had a profound impact in the diet compared to HC, reducing the consumption of dairy (OR=0.32, p<0.0001), bread and/or whole grain cereals (OR=0.59, p=0.0006), fresh fruit (OR=0.66, P=0.008), and fish (OR=0.64, p=0.002). These same four food groups were also significantly reduced in FM patients in comparison to RA patients (p<0.0005 in all cases). Additionally, a lower consumption of pasta, rice and/or potatoes was also observed in FM compared to RA (OR=0.72, p=0.028). CONCLUSIONS: The present cross-sectional study shows that FM is associated to a significant change in the normal dietary patterns. These results underscore the importance of diet in this prevalent disease and are a warning of the potential long-range effects of a deficient nutritional status.
Assuntos
Artrite Reumatoide , Fibromialgia , Artrite Reumatoide/diagnóstico , Artrite Reumatoide/epidemiologia , Estudos Transversais , Dieta/efeitos adversos , Comportamento Alimentar , Fibromialgia/diagnóstico , Fibromialgia/epidemiologia , HumanosRESUMO
We have assessed the effect of copepod chemical cues on the diel feeding rhythms of heterotrophic and mixotrophic marine protists. All phagotrophic protists studied exhibited relatively high diurnal feeding rates. The magnitude of the diel feeding rhythm, expressed as the quotient of day and night ingestion rates, was inversely related to the time that phagotrophic protists were maintained in the laboratory in an environment without predators. In the case of the recently isolated ciliate Strombidium arenicola, the rhythm was lost after a few months. When challenged with chemical alarm signals (copepodamides) from the copepod Calanus finmarchicus at realistic concentrations (0.6-6 pM), S. arenicola partially re-established diurnal feeding. Conversely, the amplitude of the diel feeding rhythm for the ciliate Mesodinium rubrum was not affected by copepodamides, although the 24-h integrated food intake increased by approximately 23%. For the dinoflagellates Gyrodinium dominans and Karlodinium armiger, copepodamides significantly reduced the amplitude of their diel feeding rhythms; significant positive effects on total daily ingestion were only observed in G. dominans. Finally, the dinoflagellate Oxyrrhis marina, isolated >20 years ago, showed inconsistent responses to copepodamides, except for an average 6% increase in its total ingestion over 24 h. Our results demonstrate that the predation risk by copepods affects the diel feeding rhythm of marine protists and suggests a species-specific response to predation threats.
Assuntos
Cilióforos , Dinoflagellida , Animais , Sinais (Psicologia) , Comportamento Alimentar , Comportamento PredatórioRESUMO
OBJECTIVE: Burnout among physicians has increased, affecting not only doctors but also the quality of patient care. Treating challenging disorders, such as fibromyalgia, may increase the risk of feeling burned out. Health care of fibromyalgia patients is increasingly being assigned to family physicians. Therefore, we described the demographic characteristics, work contexts, component burnout scores (exhaustion, depersonalization, and personal accomplishment), and perceptions of fibromyalgia care of Spanish family medicine physicians with high and low levels of burnout. We then evaluated which of these variables were associated with having high or low levels of burnout. METHOD: This cross-sectional study assessed 506 family physicians recruited from the Spanish Society of Family Physicians and randomly selected from Primary Health Care Centers. The subgrouping of family physicians based on their burnout scores was assessed by cluster analysis. Variables showing statistically significant differences between clusters and significance below 0.25 in univariate logistic regressions were assessed by multivariate logistic regression analysis. RESULTS: Family physicians reporting higher burnout scores (25%) felt that fibromyalgia patients on sick leave increased their workload, reported no support from nurses in the treatment of fibromyalgia patients, and had a more negative impression of fibromyalgia patients. CONCLUSIONS: One-quarter of family physicians reported feeling exhausted, detached from fibromyalgia patients, or less professionally accomplished. Several personal characteristics and contextual variables increased burnout. Several interventions to modify these variables and, thus, protect family physicians treating fibromyalgia from burnout are suggested.
Assuntos
Esgotamento Profissional , Fibromialgia/terapia , Médicos de Família , Esgotamento Profissional/epidemiologia , Esgotamento Psicológico , Estudos Transversais , Fibromialgia/diagnóstico , Humanos , Satisfação no Emprego , Qualidade da Assistência à Saúde/tendências , Espanha/epidemiologia , Inquéritos e QuestionáriosRESUMO
Temporal programs synchronised with the daily cycle are of adaptive importance for organisms exposed to periodic fluctuations. This study deepens into several aspects of the exogenous and endogenous nature of microbial grazers. We investigated the diel rhythms of cell division and feeding activity of four marine protists under different light regimes. In particular, we tested if the feeding cycle of protistan grazers could be mediated by a light-aided enhancement of prey digestion, and also explored the consequences of cell division on diel feeding rhythms. Cell division occurred at night for the heterotrophic dinoflagellates Gyrodinium dominans and Oxyrrhis marina. In contrast, the mixotrophic dinoflagellate Karlodinium armiger and the ciliate Strombidium sp. mostly divided during the day. Additionally, a significant diurnal feeding rhythm was observed in all species. When exposed to continuous darkness, nearly all species maintained the cell division rhythm, but lost the feeding cycle within several hours/days (with the exception of O. marina that kept the rhythm for 9.5 days). Additional feeding experiments under continuous light also showed the same pattern. We conclude that the feeding rhythms of protistan grazers are generally regulated not by cell division nor by the enhancement of digestion by light. Our study, moreover, indicates that the cell division cycle is under endogenous control, whereas an external trigger is required to maintain the feeding rhythm, at least for most of the species studied here.
Assuntos
Cilióforos/fisiologia , Dinoflagellida/fisiologia , Divisão Celular/efeitos da radiação , Cilióforos/efeitos da radiação , Dinoflagellida/efeitos da radiação , Processos Heterotróficos , LuzRESUMO
Animals fight over resources such as mating partners, territory, food or shelter and repeated contests lead to stable social hierarchies in different phyla. The group dynamics of hierarchy formation are not characterized in the Norway lobster (Nephrops norvegicus). Lobsters spend most of the day in burrows and forage outside of them according to a diel (i.e. 24â h-based) activity rhythm. Here, we use a linear and generalized mixed model approach to analyse, in seven groups of four male lobsters, the formation of dominance hierarchies and rank-related changes in burrowing behaviour. We show that hierarchies emerge within 1-3â days and increase in steepness over a period of 5â days, while rank changes and number of fights gradually decrease over a 5-day period. The rank position determined by open area fights predicts the outcome of fights over burrows, the time spent in burrows, and the locomotor activity levels. Dominant lobsters are more likely to evict subordinate lobsters from their burrows and are more successful in defending their own burrows. They spend more time in burrows and display lower levels of locomotor activity outside the burrow. Lobsters do not change their diel activity rhythms as a result of a change in rank, and all tested individuals showed higher activity at night and dusk compared with dawn and daytime. We discuss how behavioural changes in burrowing behaviour could lead to rank-related benefits such as reduced exposure to predators and energy savings.
Assuntos
Comportamento Animal , Nephropidae/fisiologia , Animais , Ritmo Circadiano , Comportamento Competitivo , Hierarquia Social , MasculinoRESUMO
OBJECTIVE: To assess the transcultural equivalency of the Spanish version of the Fibromyalgia Rapid Screening Tool (FiRST) and its discriminatory ability in different Latin American samples. DESIGN: Validation study. SETTING: Departments of Rheumatology in general hospitals and private centers; fibromyalgia unit in a university hospital. SUBJECTS: 350 chronic pain patients from Spain, Argentina, Mexico, Peru, and Ecuador. METHODS: The cultural relevance of the Spanish version of the FiRST was evaluated. The ability of the FiRST as a screening tool for fibromyalgia was assessed by logistic regression analysis. To determine the degree to which potential confounders, such as differences in demographics, pain, affective distress, catastrophizing, and disability, might affect the discriminatory ability, the tool was reassessed by hierarchical multivariate logistic regression. RESULTS: Slightly different versions of the FiRST were recommended for use in each Latin American subsample. The FiRST showed acceptable criterion validity and was able to discriminate between fibromyalgia and non-fibromyalgia patients even after controlling for the effect of potential confounders. However, low specificities were observed in samples from Spain and Mexico. CONCLUSIONS: The Spanish version of the FiRST may be used as a screening tool for fibromyalgia in several Latin American subsamples, even in those patients with high scores on potential confounders. In Spain and Mexico, the low specificity of the FiRST suggests, however, that it would be best used to support a suspected diagnosis of fibromyalgia, rather than to exclude the diagnosis.
Assuntos
Comparação Transcultural , Fibromialgia/diagnóstico , Fibromialgia/etnologia , Internacionalidade , Medição da Dor/normas , Inquéritos e Questionários/normas , Adulto , Idoso , Argentina/etnologia , Equador/etnologia , Humanos , México/etnologia , Pessoa de Meia-Idade , Medição da Dor/métodos , Peru/etnologia , Reprodutibilidade dos Testes , Espanha/etnologiaRESUMO
OBJECTIVES: The objectives were to compare the personality of fibromyalgia (FM) patients with other chronic painful and nonpainful disorders considering the confusion due to psychopathology and to assess the clustering of FM patients according to their personality profile. METHODS: Differences in the NEO Five-Factor Inventory between FM, non-FM chronic pain and drug-resistant epileptic patients were assessed including the confounding effect of demographics and psychopathological status by multivariate regression analysis. Clustering of FM patients was assessed by two-step cluster analysis. Differences in clinical severity and psychosocial problems between subgroups and their outcome 6 months after multidisciplinary treatment were assessed. RESULTS: The final sample comprised 874 patients. Once the effect of confounding variables was considered, clinically nonsignificant differences in personality were observed between groups. FM patients could, however, be grouped into two clusters. Cluster 1 was characterized by higher neuroticism and lower extraversion and showed a worse pretreatment clinical state including more psychosocial problems. In spite of having reached a wider general improvement at 6-month follow-up, Cluster 1 patients remained more anxious and depressed. CONCLUSIONS: Identifying personality-based subgroups of FM might allow implementing specific preventive strategies. FM treatment might be optimized by increasing medication compliance, improving therapeutic alliance and testing different therapeutic options and treatment sequencing for each personality subgroup.
Assuntos
Dor Crônica/psicologia , Fibromialgia/psicologia , Personalidade , Adulto , Ansiedade/psicologia , Transtornos de Ansiedade , Estudos de Casos e Controles , Análise por Conglomerados , Depressão/psicologia , Epilepsia/psicologia , Extroversão Psicológica , Feminino , Fibromialgia/terapia , Humanos , Masculino , Pessoa de Meia-Idade , Análise Multivariada , Neuroticismo , Medição da Dor , Inventário de Personalidade , Análise de Regressão , Doenças Reumáticas/psicologia , Índice de Gravidade de Doença , Resultado do TratamentoRESUMO
OBJECTIVE: Despite showing acceptable psychometric properties, the criterion validity of the original Fibromyalgia Rapid Screening Tool (FiRST) has been called into question for including insufficiently challenging comparison groups. Consequently our objective was to validate a Spanish version of the FiRST including pain disorders more analogous to fibromyalgia. METHODS: The FiRST was translated following international standards. Internal consistency and temporal stability were assessed. The ability of the FiRST global score as a screening tool for fibromyalgia (criterion validity) was assessed by logistic regression analysis. To determine the degree to which potential confounders might affect the criterion validity of the FiRST (divergent validity), it was reassessed by hierarchical multivariate logistic regression, entering demographics in a first step, followed by pain, anxiety and depression, catastrophizing, disability and the FiRST global score in a last step. RESULTS: The final sample comprised 257 patients (67% cases of fibromyalgia). The Spanish version of the FiRST showed acceptable internal consistency, reliability and criterion validity. The FiRST was able to discriminate between fibromyalgia and non-fibromyalgia patients even after controlling for the effect of potential confounders. However, both criterion and divergent validity were challenged by a moderate specificity. CONCLUSION: The Spanish version of the FiRST may be used as a screening tool for fibromyalgia even in those patients whose cognitive style is characterized by catastrophizing about pain and high levels of functional disability, anxiety and depression. The clinical consequences of the moderate specificity shown by this Spanish version of the FiRST are discussed.
Assuntos
Fibromialgia/diagnóstico , Inquéritos e Questionários/normas , Traduções , Dor Crônica/etiologia , Diagnóstico Precoce , Feminino , Humanos , Idioma , Masculino , Pessoa de Meia-Idade , Medição da Dor/métodos , Medição da Dor/normas , Psicometria , Curva ROC , Reprodutibilidade dos TestesRESUMO
Introducción. Existen sólidas pruebas de la relevancia del miedo, la ansiedad y la evitación de la actividad en el mantenimiento del dolor en la fibromialgia. Recientemente se ha descrito un modelo opuesto basado en la persistencia en la actividad. Actualmente desconocemos las cogniciones que dificultan la modificación de este patrón de comportamiento. Por consiguiente, el objetivo del estudio es la definición consensuada del contenido de un instrumento que las evalúa. Material y métodos. Mediante consulta prospectiva a expertos se consensuó el contenido del Cuestionario Clínic de Persistencia en la Actividad en la Fibromialgia (CCAP-FM). Resultados. Tras 3 rondas de consulta se alcanzó un acuerdo aceptable. Se excluyeron los ítems que obtuvieron una valoración media consensuada de relevancia inferior a 5/10 y que al menos el 75% de los expertos recomendó eliminar. El cuestionario preliminar de persistencia en la actividad quedó compuesto por 30 ítems. Conclusiones. La definición del contenido del CCAP-FM permitirá iniciar el proceso de evaluación de la relación entre la modificación de las cogniciones responsables del mantenimiento de la persistencia en la actividad y la mejoría clínica de las personas con fibromialgia(AU)
Background and objective. There is evidence of the relevance of fear, anxiety and avoidance of activity in the maintenance of pain in fibromyalgia. Recently, an opposite pattern based on the persistence in activity has been described. To date, the cognitions that impede modifying this pattern are unknown. Therefore, the aim of this study is to reach consensus on the content of an instrument that assesses those cognitions. Material and methods. A Delphi method was applied to reach consensus on the content of the Clinic Scale of Persistence in Activity in Fibromyalgia (CCAP-FM). Results. After three rounds of consultation, an acceptable consensus was reached. Those items that received an average rating of relevance lower than 5/10 and that at least the 75% of experts recommended removing were excluded. The preliminary questionnaire of persistence in activity was composed of 30 items. Conclusions. The consensus on the content of the CCAP-FM will allow advancing towards the assessment of the relation between the modification of the cognitions responsible for the maintenance of the persistence in activity and the clinical improvement in people with fibromyalgia(AU)
Assuntos
Humanos , Masculino , Feminino , Fibromialgia/complicações , Fibromialgia/psicologia , Dor/psicologia , Pesquisa Comportamental/métodos , Escalas de Graduação Psiquiátrica Breve/estatística & dados numéricos , Escalas de Graduação Psiquiátrica Breve/normas , Medo/psicologia , Padrões de Referência , Estudos Prospectivos , Inquéritos e Questionários , Psicologia Clínica/métodos , Psicologia Clínica/tendências , Ansiedade/psicologia , Transtornos de Ansiedade/psicologiaRESUMO
BACKGROUND AND OBJECTIVE: There is evidence of the relevance of fear, anxiety and avoidance of activity in the maintenance of pain in fibromyalgia. Recently, an opposite pattern based on the persistence in activity has been described. To date, the cognitions that impede modifying this pattern are unknown. Therefore, the aim of this study is to reach consensus on the content of an instrument that assesses those cognitions. MATERIAL AND METHODS: A Delphi method was applied to reach consensus on the content of the Clinic Scale of Persistence in Activity in Fibromyalgia (CCAP-FM). RESULTS: After three rounds of consultation, an acceptable consensus was reached. Those items that received an average rating of relevance lower than 5/10 and that at least the 75% of experts recommended removing were excluded. The preliminary questionnaire of persistence in activity was composed of 30 items. CONCLUSIONS: The consensus on the content of the CCAP-FM will allow advancing towards the assessment of the relation between the modification of the cognitions responsible for the maintenance of the persistence in activity and the clinical improvement in people with fibromyalgia.
Assuntos
Técnica Delphi , Fibromialgia/psicologia , Atividade Motora , Testes Psicológicos , Feminino , Humanos , MasculinoRESUMO
This study assessed the ability of the Symptom Checklist-Revised (SCL-90-R) to discriminate between two groups of fibromyalgia patients (those who were about to begin a treatment including the explicit aim of returning to work and those who were initiating a legal procedure to obtain permanent disability compensation) and two groups of healthy volunteers (medical students and psychology graduates), who were asked to produce a symptomatic resemblance to a chronic pain disorder. Logistic regression analyses were applied to the SCL-90-R subscales and individual probabilistic indices of simulation were calculated. Results showed that the SCL-90-R was able to discriminate between healthy subjects and both groups of patients with a high sensitivity and specificity. The individual indices of simulation, which might be more useful in clinical practice than the comparison of the SCL-90-R profiles, also showed an appropriate level of accuracy.
Assuntos
Fibromialgia/diagnóstico , Simulação de Doença/diagnóstico , Inquéritos e Questionários , Adulto , Atitude Frente a Saúde , Transtornos Cognitivos/diagnóstico , Tomada de Decisões , Diagnóstico Diferencial , Avaliação da Deficiência , Feminino , Comportamentos Relacionados com a Saúde , Humanos , Masculino , Testes Neuropsicológicos , Índice de Gravidade de Doença , EstereotipagemRESUMO
OBJECTIVE: To assess the influence of the pain locus of control on return to work in fibromyalgia patients. METHODS: Ninety-eight fibromyalgia patients on sick leave were enrolled in a multidisciplinary treatment program and were followed up for 12 months post-discharge. Treatment was considered successful at discharge in the case of patients who returned to work and unsuccessful in patients who remained sick listed. Treatment was considered successful during follow-up in patients who remained at work for at least the last 6 months of follow-up. Patients who took sick leave again and those lost to follow-up were considered failures. Logistic regression methods were used to define the best predictive models of treatment failure. RESULTS: Fifty-eight patients were considered treatment successes at discharge and 50 at 12-month follow-up. The subscale Fate from the Multidimensional Health Locus of Control-Pain Scale and the Health Assessment Questionnaire predicted treatment failure at discharge (-2lnR=57.79; chi-square=74.74; df=2; P<.001). The predictive model of treatment failure at 12-month follow-up was unspecific. CONCLUSION: Fibromyalgia patients undergoing a multidisciplinary treatment who were least likely to return to work at discharge were those with a pain locus of control characterized by more negative expectations about pain progression and a high perceived functional disability.