Pancreatic involvement detected with (18)F-FDG PET/CT in disseminated sarcoidosis.

La sarcoidosis is a granulomatous disease of unknown etiology. It may mimic malignancy and may affect multiple organs, with a variable clinical course. Pancreatic involvement is very rare. We present the case of a 78-year-old woman with systemic sarcoidosis whose (18)F-FDG PET/CT scan showed a pancreatic lesion and multiple lymphatic (thoracic and non-thoracic) and visceral lesions. The abnormal (18)F-FDG uptake in the pancreas was limited to the tail. A second (18)F-FDG PET/CT study performed 4 months and 3 weeks after the first PET/CT, following corticosteroid therapy during three and a half months, evidenced partial regression of the disease, with persistent (18)F-FDG pathological uptake in the pancreatic lesion.

Sobre algunos términos de uso frecuente en Medicina Nuclear / On some terms of frequent use in nuclear Medicine

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¿Dónde se publica la investigación sobre medicina nuclear? / Where is the research on Nuclear Medicine published?

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[The Spanish Journal of Nuclear Medicine: from 1991 to 2000]. / La Revista Española de Medicina Nuclear: de 1991 a 2000.

OBJECTIVE: To describe the articles published in "Revista Española de Medicina Nuclear" (REMN) from 1991 through 2000. MATERIAL AND METHODS: Five hundred and forty-two articles (originals, reviews, editorials, letters, clinical notes and images of interest) published in REMN during the past 10 years (1991-2000) were gathered. The following variables were assessed: topic, procedure, type of article, number of authors, Spanish region affiliation, country, number of pages and number of references. The results for the five year periods 1991-1995 and 1996-2000 were also presented. RESULTS: Excluding the editorial contributions, the most dealt with topic was the osteoarticular system (14.9%), followed by the heart (14.2%), endocrinology (12.1%), gastroenterology (11.3%) and neurology (10,3%). One hundred and thirty articles were linked to oncology. Madrid (23.7%), Catalonia (22.5%), Andalucia (10.6%) and Aragon (10.1%) were the Spanish regions that made the most contributions. Conventional planar scintigraphic studies were the most used procedure (49.1%), followed by SPECT (16.6%). The countries that were represented most were Spain and Cuba, with 410 and 36 works, respectively. The global trend underwent little change in the above variables in the decade. The pages/paper index was 6.1 +/- 1.7 for original papers and 6.5 +/- 4.3 for reviews. The authors/paper index was 6.3 +/- 2.3 for original papers and 2.7 +/- 2.1 for reviews. The references/paper index was 21.9 +/- 11.4 for original papers and 3+/- 1.1 39.6 for reviews. These three indexes increased in all sections between the periods 1991-1995 and 1996-2000. CONCLUSIONS: This survey shows subtle qualitative changes throughout the period analyzed. A quantitative increase in the scientific production in the REMN seems to exist. However, many factors must be considered in the final evaluation of these results and this remains beyond the scope of this descriptive work.

La Revista Española de Medicina Nuclear: de 1991 a 2000 / The Spanish Journal of Nuclear Medicine: from 1991 to 2000

Objetivo: Describir los artículos publicados en la Revista Española de Medicina Nuclear (REMN) desde 1991 hasta el 2000.Material y Métodos: Se recogieron 542 artículos (originales, revisiones, editoriales, cartas, notas clínicas e imágenes de interés) publicadas en la REMN en los pasados 10 años (1991-2000). Se definieron las siguientes variables: temas, técnicas empleadas, tipo de artículo, número de autores, comunidad autónoma española de origen, país, número de páginas y número de referencias. Se mostraron también los datos correspondientes a los quinquenios 1991-1995 y 1996-2000.Resultados: Excluyendo los editoriales, el tema más tratado fue el aparato osteoarticular (15,9 per cent), seguido por corazón (14,2 per cent), endocrinología (12,1 per cent), gastroenterología (11,3 per cent) y neurología (10,3 per cent). Ciento treinta artículos versaron sobre oncología. Madrid (23,7 per cent), Cataluña (22,5 per cent), Andalucía (10,6 per cent) y Aragón (10,1 per cent) fueron las comunidades que hicieron más contribuciones. Los estudios gammagráficos planares convencionales fueron la técnica más empleada (49,1 per cent), seguidos por los estudios con SPECT (16,6 per cent). Los países representados mayoritariamente fueron España y Cuba, con 410 y 36 trabajos, respectivamente. La tendencia global sufrió pocas variaciones en las anteriores variables a lo largo del decenio. El índice de páginas/artículo fue de 6,1 ñ 1,7 para originales y de 6,5 ñ 4,3 para revisiones. El índice de autores/artículo fue de 6,3 ñ 2,3 para originales y 2,7 ñ 2,1 para revisiones. El índice de referencias/artículo fue de 21,9 ñ 11,4 para originales y 31,1 ñ 39,6 para revisiones. Estos tres índices aumentaron en todas las secciones entre los períodos 1991-1995 y 1996-2000.Conclusiones: Existen cambios cualitativos discretos a lo largo del período analizado. Parece existir un incremento cuantitativo en la producción científica de la REMN. Sin embargo, la valoración final de estos resultados debe tener en cuenta muchos factores, lo cual está más allá del propósito descriptivo de este trabajo (AU)

[Estimating the angiographic risk from isotopic ventriculography in ischemic heart disease]. / Estimación del riesgo angiográfico a partir de la ventriculografía isotópica en cardiopatía isquémica.

The objective of this study was to determine the diagnostic accuracy of the ejection fraction (EF) measurement, calculated by isotopic ventriculography, to predict the angiographic risk in a group of patients with previous acute myocardial infarction and significant segmentary disturbance of wall motility. A total of 125 patients were studied (100 males and 25 females, aged 23 to 78 years). Isotopic EF showed positive and negative predictive values of 85% and 93.3%, respectively, for the low risk group. The corresponding values for the moderate risk group (angiographic EF from 31% to 54%) were 80.3% and 79.6%. And for the high risk group (angiographic EF < 31%) 89.4% and 83%. In conclusion, from the present work we state that with a high probability isotopic EF places each patient in his/her corresponding high, moderate, or low angiographic (biological) risk.

[Relation between frontal lobe blood flow and cognitive performance in Huntington's disease]. / Relación entre flujo sanguíneo cerebral frontal y rendimiento cognitivo en la enfermedad de Huntington.

The aim of this study was to trace the possible relation between degree of cognitive impairment in Huntington's disease (HD) and cortical cerebral blood flow. We studied 18 patients with genetically confirmed HD, evaluating clinical signs and performance on neuropsychological tests. SPECT with 99mTc-HMPAO was used to quantify regional cerebral blood flow (rCBF) in 8 regions in each hemisphere. We found no correlation between clinical or cognitive variables and rCBF in temporal, parietal or occipital areas. Cognitive performance on several tasks correlated significantly with rCBF (p < 0.05 or p < 0.01) in numerous frontal areas with the exception of orbital gyri. These data suggest that frontal lobe dysfunction is implicated in the pathogenesis of cognitive impairment in HD, and that such impairment can be explained by the involvement of frontal-subcortical loops.