[Dynamics of ultrastructural organization of liver cells in experimental peritonitis].

In the experiment on Wistar rats by methods of light and electron microscopy an ultrastructural disorders of the liver cells in various stages of peritonitis were investigated. It was shown that the reactive phase of experimental peritonitis associates with dystrophic changes of the hepatocytes and the endotheliocytes of sinusoids. These reversible changes are explained by an adaptive response of cells to inflammation. In the toxic and especially in the terminal stages of peritonitis in submicroscopical architectonics of the hepatocytes, Kupffer cells and sinusoidal endotheliocytes, along with dystrophic changes appear destructive violations of organelles of hepatic cells that acquired an irreversible character. The proposed model let description of ultrastructural and functional disorders of the liver cells at different stages of peritonitis.

[Reaction of regional abdominal blood flow in peritonitis to vasoactive medication based on data of selective angiography and rheography]. / Reaktsiia regional'nogo abdominal'nogo krovotoka pri peritonite na primenenie vazoaktivnykh preparatov po dannym selektivnoi angiografii i reografii.

With the help of selective arteriography of the mesenteric vessels and rheography it was found that patients with peritonitis are characterized by a reduction of blood flow in the superior mesenteric artery as a result of a spasm of the artery and its branches in the small intestine wall. This reaction is functional and can be eliminated or attenuated by purposeful measures, the most effective of them being prolonged peridural anesthesia (PPA) and droperidol injections. Thus the both methods of correction of the peritonitis dynamics (PPA and droperidol) can block up the transition of the reactive stage of peritonitis to toxic. The use of regional rheography is thought to be more expedient in medical practice than selective angiography for the assessment of the character of mesenteric blood flow in operated peritonitis patients as a more accessible and safe method for multiple performances.

[Laser seromyotomy of the stomach in duodenal ulcers]. / Lazernaia seromiotomiia zheludka pri iazve dvenadtsatiperstnoi kishki.

The use of laser surgical equipment permits to simplify considerably a method of gastric seromyotomy. On the basis of the results of treating 38 patients, the optimal parameters of laser energy, used in dissection of the gastric wall, are recommended, the advantages and shortcomings of the different sources of radiation are studied.

[A method of laser seromyotomy of the stomach]. / Tekhnika lazernoi seromiotomii zheludka.

A technique of laser seromyotomy was developed as a method for vagus denervation for the treatment of gastroduodenal ulcers. Soviet Raduga neodymium YAG laser and foreign Medilaz and Flexilas units were employed as sources of laser irradiation. The operation was performed in the 'contact scalpel' mode with the use of Soviet sapphire tips. The developed technique permits seromyotomy that results in better hemostasis and lower risk of gastric submucosal layer involvement vs. electronomo suggested earlier by Taylor, an English surgeon. Twelve patients were operated on; one developed intraperitoneal hemorrhage that ceased independently.