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1.
J Pediatr ; 257: 113384, 2023 06.
Artigo em Inglês | MEDLINE | ID: mdl-36931493

RESUMO

OBJECTIVES: To evaluate the effectiveness of newborn screening for sickle cell disease in eastern Jamaica by determining what proportion of screen-positive infants were registered with the Sickle Cell Unit by 2 months (60 days) of age and identifying parents' perceptions of facilitators and barriers impacting age at registration. STUDY DESIGN: This cross-sectional study used a mixed method approach. Ages at diagnosis confirmation and first clinic visit were recorded for screen-positive infants born between February 1, 2015, and November 15, 2017. All parents were invited to complete the survey, and early and late attendees were invited to participate in the qualitative aspect of the study. A researcher-designed questionnaire and an interview guide based on the Capability, Opportunity, Motivation, Behavior, and health belief models examined factors that may affect time to registration. Quantitative data were analyzed to yield descriptive statistics using Stata®v14. All interview data were coded. Similar codes were grouped together into themes. RESULTS: Most (97.7%) of the 133 screen-positive infants had their diagnosis confirmed. Only 40% had their first clinic visit by age 60 days. Denial of the diagnosis, poor communication, and the costs of treatment and transportation were perceived barriers to registration, whereas family support was a facilitator. CONCLUSIONS: Diagnosis confirmation was almost universal, but most infants did not attend clinic by 2 months of age. In-depth interviews have identified several facilitators and barriers that can be targeted to improve early registration.


Assuntos
Anemia Falciforme , Recém-Nascido , Humanos , Lactente , Jamaica , Estudos Transversais , Anemia Falciforme/diagnóstico , Triagem Neonatal , Pais
2.
Pediatr Blood Cancer ; 70(3): e30161, 2023 03.
Artigo em Inglês | MEDLINE | ID: mdl-36579755

RESUMO

BACKGROUND: Patients with homozygous sickle cell disease (HbSS) and clinical splenomegaly by 6 months of age appeared at greater risk of invasive infections after 5 years of the Jamaican Cohort Study. We determined whether this risk remained significant over a longer study period, using a more rigorous definition of infection and examining the contribution of potential confounders. METHODS: Newborn screening of 100,000 consecutive deliveries during 1973-1981 detected 311 births with HbSS. Age at first clinical splenomegaly was used to categorize 285 of these patients in whom this could be determined: at or before 7 months (early), after 7 months (later), or 'never' palpated despite repeated examinations. Infective episodes were confined to 'first infections confirmed by positive culture'. Using a generalized linear model, the risk of septicaemia was assessed in each group, after adjusting for potential confounders. RESULTS: Of 93 'first infections', 42 occurred in 105 subjects in the 'early' group, 49 in 157 subjects in the 'later' group, and two in 23 subjects in the 'never' group; the observed to expected ratio of 1.42, 0.90 and 0.22 was highly significant (p = .003). Assessed as risk ratios, 'early' splenomegaly had a significantly higher risk ratio (RR) for septicaemia (RR = 7.4, confidence interval [CI]: 1.1-50.7, p < .05) when compared to the 'never' group adjusting for vaccine exposure and foetal haemoglobin concentration. The most common organisms were Streptococcus pneumoniae, Salmonella species, Haemophilus influenzae and Staphylococcus aureus. CONCLUSION: Early clinical splenomegaly in HbSS remains a predictor of septicaemia, defining a group that may require closer monitoring.


Assuntos
Anemia Falciforme , Sepse , Recém-Nascido , Humanos , Pré-Escolar , Estudos de Coortes , Esplenomegalia/epidemiologia , Esplenomegalia/etiologia , Sepse/epidemiologia , Sepse/etiologia , Anemia Falciforme/complicações , Homozigoto
3.
Psychol Health Med ; 24(4): 470-480, 2019 04.
Artigo em Inglês | MEDLINE | ID: mdl-30318923

RESUMO

The current study examines gender effects on disease knowledge and quality of life in adolescents with sickle cell disease (SCD) in Jamaica. We report the baseline results on 76 girls and 74 boys with mean age (16.9 ± 1.8 vs. 16.2 ±2.0 years), recruited in a larger intervention study. Girls had higher knowledge scores (15.3 ± 4.2 vs. 13.3 ± 4.2 p=.004), poorer overall QOL scores (70.1 ± 19.6 vs. 77.2 ± 17.8 p=0.02) but similar severity scores to boys. Girls also had significantly lower scores on many QOL domain scores: Pain occurrences over the course the past month (Pain and Hurt:77.49 ± 23.3 vs. 85.37 ± 17.13); concerns about seeking health services for pain (Worry1:63.73 ± 26.21 vs. 75.33 ± 24.62); confidence in self-management & treatment effects (Treatment: 72.25 ± 23.6 vs. 80.73 ± 18.90) and SCD disclosure & empathy from others (Communication II: 47.44 ± 1.02 vs. 61.71 ± 29.41). Knowledge was positively predicted by age, higher education, greater household possessions and was higher in girls; whereas QOL was lower in girls and those with greater disease severity and higher with higher education. In conclusion, there is a significant gender differential in disease knowledge and QOL among adolescents with SCD. Interventions will need to address the lower QOL in girls and lower disease knowledge among boys.


Assuntos
Anemia Falciforme/psicologia , Qualidade de Vida , Adolescente , Feminino , Conhecimentos, Atitudes e Prática em Saúde , Humanos , Jamaica , Masculino , Análise de Regressão , Autogestão , Fatores Sexuais , Inquéritos e Questionários
4.
Child Care Health Dev ; 44(3): 501-506, 2018 05.
Artigo em Inglês | MEDLINE | ID: mdl-29436011

RESUMO

BACKGROUND: Increasing knowledge and understanding of disease is known to improve outcomes in persons living with a chronic illness. In this paper, we aim to compare the disease knowledge of children with sickle cell disease (SCD), age 6-10 years, who received an intervention (an educational colouring book on SCD) geared towards improving disease knowledge, to those who did not received the colouring book. METHODS: A quasi-experimental study was conducted where disease knowledge was determined in 56 children who had received the colouring book and compared to 60 children who did not receive this intervention. RESULTS: The mean knowledge score was significantly higher in the intervention group (mean difference = 2.65; 95% CI [1.43, 3.86]), as well as in older children and in those in higher grades but there was no difference between sexes. In a multiple regression model (adjusted R2 : 0.39; p value < .001), knowledge score was significantly higher in those who received the intervention (ß: 2.62; 95% CI [1.48, 3.76]) while adjusting for age, gender, persons living at home, and the father's employment status. CONCLUSION: The study highlights that a simple, inexpensive (cost: US$1/book) child-friendly intervention can significantly improve knowledge about SCD even in young children. It also underlines various social factors that are associated with children's understanding of their disease.


Assuntos
Anemia Falciforme/psicologia , Serviços de Saúde da Criança , Conhecimentos, Atitudes e Prática em Saúde , Educação de Pacientes como Assunto , Anemia Falciforme/economia , Criança , Serviços de Saúde da Criança/economia , Serviços de Saúde da Criança/organização & administração , Análise Custo-Benefício , Feminino , Inquéritos Epidemiológicos , Humanos , Jamaica , Masculino , Educação de Pacientes como Assunto/economia , Educação de Pacientes como Assunto/métodos
5.
Indian J Tuberc ; 64(1): 47-49, 2017 01.
Artigo em Inglês | MEDLINE | ID: mdl-28166917

RESUMO

Mycobacterium tuberculosis apart from being the causative agent of pulmonary tuberculosis is also notorious to cause tuberculosis at various sites in the human body and ocular tuberculosis is one of the extra pulmonary manifestations of this organism. The most common presentation of ocular tuberculosis is anterior uveitis or choroiditis caused by hematogenous infection or hypersensitivity after another organ infection. Eyelid involvement by tuberculosis is most of the times secondary to orbital involvement and often seen in the form of drainage sinus. Isolated eyelid tuberculosis is however uncommon. Here we report two such cases of eyelid tuberculosis in different age groups; first case in a young female and second case of an old aged female with different presentation. Fortunately both of them responded well to the antitubercular treatment.


Assuntos
Doenças Palpebrais/diagnóstico , Tuberculose Ocular/diagnóstico , Antituberculosos/uso terapêutico , Diagnóstico Diferencial , Doenças Palpebrais/tratamento farmacológico , Feminino , Humanos , Pessoa de Meia-Idade , Tuberculose Ocular/tratamento farmacológico , Adulto Jovem
6.
Niger J Clin Pract ; 18(3): 411-5, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-25772928

RESUMO

AIMS: The aim was to evaluate the incidence of root fracture of endodontically treated teeth reinforced with glass-fiber posts and metal posts luted with different luting cements. MATERIALS AND METHODS: Forty maxillary central incisors were sectioned at 1 mm of the cementoenamel junction and endodontically treated. The teeth were divided into four groups (n = 10) and restored with prefabricated metal posts and glass-fiber posts luted with resin-based luting cement and glass ionomer cement. Core built up was done using composite resin. The fracture strength was evaluated using an Instron universal testing machine (Model 4206, Instron Corp., Canton, MA). The results were recorded. STATISTICAL ANALYSIS USED: The Kruskal-Wallis test analysis test was used to analyze the data. RESULTS: Prefabricated metal post was statistically superior to the glass-fiber posts. Posts luted with resin-based luting cement were superior in fracture strength than glass ionomer cement. CONCLUSIONS: Teeth restored with prefabricated metal posts present higher fracture strength than those reinforced with glass-fiber posts. Posts luted with resin-based luting cement showed higher fracture strength than glass ionomer cement.


Assuntos
Resinas Compostas/química , Análise do Estresse Dentário , Cimentos de Ionômeros de Vidro/química , Fraturas dos Dentes/fisiopatologia , Raiz Dentária/fisiologia , Dente não Vital , Humanos , Incisivo/fisiologia , Incisivo/cirurgia , Raiz Dentária/cirurgia
7.
In. Caribbean Public Health Agency. Caribbean Public Health Agency: 60th Annual Scientific Meeting. Kingston, The University of the West Indies. Faculty of Medical Sciences, 2015. p.[1-75]. (West Indian Medical Journal Supplement).
Monografia em Inglês | MedCarib | ID: med-17983

RESUMO

OBJECTIVES: To assess the effect of educational interventions on disease knowledge, illness perception (IP) and quality of life (QOL) of adolescents with sickle cell disease (SCD) in Kingston, Jamaica. METHODS: A randomized controlled intervention study was conducted among 150 adolescents (ages 13-19 years) attending for routine visits. Baseline disease knowledge, IP and QOL were assessed prior to randomization to 3 groups (Group A: routine care; B: educational booklet; C: booklet + formal counselling) and all measures were repeated 3 months later. Changes in outcomes were analysed using random effects analysis of variance models. RESULTS: There were 76 girls and 74 boys (Mean age 16.1ñ1.9 years; 77% had homozygous SS disease), of whom 63.3% were reviewed at three months. Baseline knowledge was higher: with age (p value: 0.007) and in girls (p value: 0.024). Teen QOL was lower in girls (p value: 0.038) and lower in severe disease (p value< 0.001). Post-intervention knowledge scores were significantly higher within all 3 groups (increase of 1.68 in group A, 2.03 in B and 2.88 in C), but there was nil effect of interventions. There were no changes in QOL or IPs either. Adolescents who had higher knowledge scores had better understanding that their illness was long lasting (Coef: 0.22; p value: 0.008), and they perceived better personal control (Coef: 0.30; p value<0.001), as well as the effect of treatment (Coef: 0.12; p value: 0.01), in managing their illness. CONCLUSIONS: Participation in the study was associated with improved knowledge scores, but interventions per say appeared to have no effects.


Assuntos
Educação , Conhecimentos, Atitudes e Prática em Saúde , Qualidade de Vida , Doença da Hemoglobina SC , Adolescente , Jamaica
8.
West Indian Med J ; 62(9): 808-16, 2013 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-25117386

RESUMO

OBJECTIVE: Whereas measurement of albumin:creatinine ratio (ACR) in spot urine samples is indicated for determining microalbuminuria, its performance or that of urinary albumin excretion rate (UAER) in predicting microalbuminuria in sickle cell disease (SCD) is unclear. We therefore tested the diagnostic performance of these measures in spot and timed urine samples in predicting a UAER in 24-hour samples. METHODS: Thirty participants with SCD had spot, two-hour and four-hour, followed by 24-hour urine collections for ACR, urinary albumin concentration (UAC) and UAER determinations. Receiver operating characteristic (ROC) curve analyses were performed. RESULTS: The areas under the ROC curves for microalbuminuria were 0.99 (CI: 0.97, 1.00) for ACR and 0.97 (CI: 0.92, 1.00) for UAC in spot urine samples. For ACR, at the cut-point of 4.13 mg/mmol, there was 100% sensitivity and 82.6% specificity, allowing an 86.2% correct classification. At the cut-point of UAC = 20.9 mg/L, there was 100% sensitivity and 73.9% specificity, allowing a 79.3% correct classification. Corresponding areas for microalbuminuria in two-hour timed samples were 0.99 (CI: 0.95, 1.00) for ACR and 0.96 (CI: 0.89, 1.00) for UAER.For ACR, the cut-point was 4.64 mg/mmol with 83.3% sensitivity and 91.3% specificity, allowing an 89.7% correct classification. Similarly for UAER, at the cut-point of 21.8 µg/min, there was 83.3% sensitivity and 91.3% specificity, allowing 89.7% correct classification. CONCLUSIONS: The diagnostic performance of ACR and UAC in a spot as well as ACR and UAER in two-hour timed urine samples in patients with SCD is excellent. Healthcare professionals can confidently utilize these measures in this patient population.

9.
West Indian Med J ; 60(2): 148-52, 2011 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-21942118

RESUMO

OBJECTIVES: Yoga improves cardiovascular health in both healthy individuals and those with diagnosed heart disease. This study compares changes in some cardiovascular parameters before and after the practice of Yoga in healthy medical students. METHODS: Sixty-four healthy medical students (57 females and 7 males), mean age 21.3 +/- 2.6 years, attending a Special Study Module 'Role of Dhyana Yoga in Stress Management', participated in this study. Systolic (SYS) and Diastolic (DIA) blood pressure, Heart Rate (HR), Stroke Volume (SV), Cardiac output (CO), Total Peripheral Resistance (TPR), Interbeat Interval (IBI), Left Ventricular Ejection Time (LVET), Arterial Compliance (Cwk) and Ascending Aorta Impedance (Zao) were measured before and after six weeks of yogic exercises. Various exercises included asanas (Postures), pranayama (Breathing), and dhyana (Meditation). Data were analyzed using Stata for Windows. RESULTS: Two-tailed paired t-test revealed that practice ofyoga caused significant increases in HR (p < 0.05), SV (p < 0.01), CO (p < 0.001) and Cwk (p < 0.01) and decreases in TPR (p < 0.001), IBI (p < 0.05) and Zao (p < 0.001) after practising yoga for 6 weeks as compared to before yoga practice. No significant differences were, however observed in SYS, DIA, Mean arterial blood pressure (MAP) and LVET CONCLUSIONS: Practice of yoga even for a short period showed ability to improve most of the cardiovascular functions. Regular practice of yoga for a longer period may further improve these functions and possibly result in improved management of their daily stress.


Assuntos
Hemodinâmica , Yoga , Feminino , Humanos , Masculino , Estresse Psicológico/fisiopatologia , Estresse Psicológico/terapia , Estudantes de Medicina , Adulto Jovem
10.
West Indian med. j ; 60(2): 148-152, Mar. 2011. tab
Artigo em Inglês | LILACS | ID: lil-672741

RESUMO

OBJECTIVES: Yoga improves cardiovascular health in both healthy individuals and those with diagnosed heart disease. This study compares changes in some cardiovascular parameters before and after the practice of Yoga in healthy medical students. METHODS: Sixty-four healthy medical students (57 females and 7 males), mean age 21.3 ±2.6 years, attending a Special Study Module 'Role of Dhyana Yoga in Stress Management', participated in this study. Systolic (SYS) and Diastolic (DIA) blood pressure, Heart Rate (HR), Stroke Volume (SV), Cardiac output (CO), Total Peripheral Resistance (TPR), Interbeat Interval (IBI), Left Ventricular Ejection Time (LVET), Arterial Compliance (Cwk) and Ascending Aorta Impedance (Zao) were measured before and after six weeks of yogic exercises. Various exercises included asanas (Postures), pranayama (Breathing), and dhyana (Meditation). Data were analyzed using Statafor WindowsTM. RESULTS: Two-tailed paired t-test revealed that practice ofyoga caused significant increases in HR (p < 0.05), SV (p < 0.01), CO (p < 0.001) and Cwk (p < 0.01) and decreases in TPR (p < 0.001), IBI (p < 0.05) and Zao (p < 0.001) after practising yoga for 6 weeks as compared to before yoga practice. No significant differences were, however, observed in SYS, DIA, Mean arterial blood pressure (MAP) and LVET. CONCLUSIONS: Practice of yoga even for a short period showed ability to improve most of the cardiovascular functions. Regular practice ofyoga for a longer period may further improve these functions and possibly result in improved management oftheir daily stress.


OBJETIVOS: El yoga mejora la salud cardiovascular tanto en individuos sanos como aquellos con diagnóstico de enfermedad cardíaca. Este estudio compara cambios en algunos parámetros cardiovasculares antes y después de la práctica del yoga en estudiantes de medicina saludables. MÉTODOS: Sesenta y cuatro estudiantes de medicina saludables (57 mujeres y 7 hombres), con una edad promedio de 21,3 ± 2.6 años, que asistían a un módulo especial de estudio "Papel de DhyanaYoga en el manejo del estrés", participaron en este estudio. Antes y después de seis semanas de ejercicios yoga, se midieron la presión arterial sistólica (SIS) y diastólica (DIA), ritmo cardíaco (RC), volumen sistólico de eyección (VS), gasto cardíaco (GC), resistencia periférica total (RPT), tiempo de intervalos interpulsos o interlatidos cardiacos (IBI), tiempo de eyección ventricular izquierda (TEVI), distensibilidad arterial Windkessel (Cwk) y la impedancia de la aorta ascendente (Zao). Los diversos ejercicios incluyeron asanas (posturas), pranayama (respiración) y dhyana (meditación). Se analizaron los datos usando Stata de Windows. RESULTADOS: La prueba T pareado de dos colas, reveló que la práctica del yoga causaba importantes aumentos del RC (p < 0,05), VS (p < 0,01), GC (p < 0,001) y Cwk (p < 0,01) y disminuciones de RTP comparación con la situación antes de la práctica de yoga. Sin embargo, no se observaron diferencias significativas en SIS, DIA, MAP y TEVI. CONCLUSIONES: La práctica del yoga incluso durante un corto período mostró capacidad para mejorar la mayoría de las funciones cardiovasculares. La práctica regular del yoga por un período más largo puede mejorar aún más estas funciones, y posiblemente traer como resultado una mejoría en el manejo del estrés cotidiano.


Assuntos
Feminino , Humanos , Masculino , Adulto Jovem , Hemodinâmica , Yoga , Estresse Psicológico/fisiopatologia , Estresse Psicológico/terapia , Estudantes de Medicina
11.
BMJ Case Rep ; 20102010 Sep 20.
Artigo em Inglês | MEDLINE | ID: mdl-22778281

RESUMO

The authors present a case of a patient with sickle-ß thalassaemia (Sß(0) Thal) who had bilateral psoas abscesses on a background of splenectomy in early childhood. The patient also turned out to have vertebral osteomyelitis and hydronephrosis on the side of the larger abscess. The only organism recovered from the patient was a Bacteroides species. The patient was managed with percutaneous drainage and intravenous antibiotics and made a full recovery.


Assuntos
Anemia Falciforme/complicações , Infecções por Bacteroides/complicações , Vértebras Lombares , Osteomielite/complicações , Abscesso do Psoas/complicações , Doenças da Coluna Vertebral/complicações , Adulto , Bacteroides , Humanos , Hidronefrose/complicações , Hidronefrose/microbiologia , Vértebras Lombares/microbiologia , Masculino , Abscesso do Psoas/microbiologia
12.
West Indian Med J ; 58(4): 357-61, 2009 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-20099777

RESUMO

Extensive research has shown that no matter how knowledgeable the physician might be, if he/she is not able to open good communication channels with the patient, he/she may be of no help to the latter Despite this known fact and the fact that a patient-physician consultation is the most widely performed 'procedure' in a physician's professional lifetime, effective communication with the patient has been found to be sadly lacking. This review article seeks to discuss 'the what', 'the why' and 'the how' of doctor-patient communication.


Assuntos
Comunicação , Relações Médico-Paciente , Competência Clínica , Humanos
13.
West Indian med. j ; 56(6): 540-543, Dec. 2007. ilus
Artigo em Inglês | LILACS | ID: lil-507250

RESUMO

Intrathoracic extramedullary haematopoiesis is a rare entity encountered in patients with long standing anaemias such as thalassaemia and congenital spherocytosis. It is rare in patients with homozygous sickle cell disease; only 11 cases of intrathoracic and two cases of pelvic extramedullary haematopoiesis have been documented in the literature. We report the case of a 30-year old man with homozygous sickle cell disease with intrathoracic and pelvic extramedullary haematopoiesis, the first case to be documented from the Caribbean.


La hematopoyesis extramedular intratorácica es una entidad que raras veces se encuentra en pacientescon anemias de larga duración tales como la talasemia y la esferocitosis congénita. También es rara en pacientes que padecen la enfermedad de células falciformes homocigóticas. En la literatura se han documentado sólo 11 casos de hematopoyesis extramedular intratorácica y dos casos de hematopoyesis extramedular pélvica. Reportamos el caso de un hombre de 30 años de edad con la enfermedad decélulas falciformes homocigóticas con hematopoyesis extramedular intratorácica y pélvica – el primercaso que se documenta en el Caribe.


Assuntos
Humanos , Masculino , Adulto , Anemia Falciforme/fisiopatologia , Hematopoese Extramedular/fisiologia , Medula Óssea/fisiologia , Evolução Fatal , Ossos Pélvicos , Vértebras Torácicas
14.
West Indian med. j ; 56(6): 491-497, Dec. 2007. tab
Artigo em Inglês | LILACS | ID: lil-507259

RESUMO

OBJECTIVES: Sickle cell disease (SCD) is the commonest genetic disorder in Jamaica and greatly affects the quality of life (QOL) of those who are afflicted. The Short Form 36 survey (SF-36) questionnaire is one of the most commonly utilized measures of QOL. Physicians cannot interpret QOL measures until the instruments being used to make assessment are adequately established in their population. The Jamaican cultural and educational systems expose its people to many stresses which likely impact on their QOL. It is thus postulated that the QOL construct may exhibit a different structure for the population with sickle cell disease. SUBJECTS AND METHODS: The SF-36 v.2 was interviewer administered to the Jamaican Sickle Cell Disease Cohort Study participants ('Cohort' sample) and a random sample of adult sickle cell unit patients ('Main'sample). Demographic data were also collected on both groups. Both of the samples did not meet the five rule criteria for compliance with the original SF-36 component structure. Hence, principal components analysis was used to determine the component structure of the SF-36 in both groups. RESULTS: Three dimensions may underlie the SF-36 for both groups and these could be labelled 'Physical Health', 'Mental Health' and 'Role Limitations'. This solution accounted for 45.8% of the variability underlying the SF-36 in the 'Cohort'sample and 54.6% of the variability in the 'Main' sample. CONCLUSIONS: It concluded that within Jamaican samples of patients with sickle cell disease, the SF-36 has a component structure which is quite distinct from that initially proposed by its creators.


Objetivos: La enfermedad de células falciformes (ECF) es el trastorno genético más común en Jamaica y afecta grandemente la calidad de vida (CdV) de quienes la padecen. El cuestionario de salud SF-36 es una de las mediciones de la CdV más comúnmente usadas. Los médicos no pueden interpretar lasmediciones de la CdV hasta que los instrumentos usados para realizar la evaluación se establezcan de forma adecuada a su población. La cultura y los sistemas educacionales en Jamaica, exponen a su población a muchas formas de estrés que afectan probablemente su CdV. De este modo, se postula que el constructo CdV puede presentar una estructura diferente para esta población. Métodos: El cuestionario SF-36 v.2 fue aplicado por el entrevistador a los participantes en un estudio de cohorte de la enfermedad de células falciformes en Jamaica (muestra de “cohorte”) y a una muestra aleatoria de pacientes adultos de la unidad de anemia falciforme (muestra “principal”). Se recogierondatos demográficos de ambos grupos. Ninguna de las muestras satisfizo los cinco criterios normativos de conformidad con la estructura original de los componentes del SF-36. Por consiguiente, se recurrió al análisis de los componentes principales a fin de determinar la estructura de componentes del SF-36 en ambos grupos. Resultados: Tres dimensiones pueden subyacer en el SF-36 para ambos grupos. Estas pueden ser llamadas “salud física”, “salud mental”, y “limitaciones de roles”. Esta solución dio cuenta del 45.8% de la variabilidad subyacente en el SF-36 en el caso de la muestra de “cohorte” y el 54.6% dela variabilidad en la muestra “principal”.Conclusiones: Se concluyó que en las muestras de pacientes de Jamaica con la enfermad de células falciformes, el SF-36 posee una estructura de componentes que puede ser bien distinta de la que inicialmente propusieron sus creadores.


Assuntos
Humanos , Masculino , Feminino , Adulto , Anemia Falciforme/epidemiologia , Anemia Falciforme/psicologia , Qualidade de Vida/psicologia , Inquéritos e Questionários , Anemia Falciforme/genética , Demografia , Jamaica/epidemiologia
15.
West Indian Med J ; 56(6): 491-7, 2007 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-18646491

RESUMO

OBJECTIVES: Sickle cell disease (SCD) is the commonest genetic disorder in Jamaica and greatly affects the quality of life (QOL) of those who are afflicted. The Short Form 36 survey (SF-36) questionnaire is one of the most commonly utilized measures of QOL. Physicians cannot interpret QOL measures until the instruments being used to make assessment are adequately established in their population. The Jamaican cultural and educational systems expose its people to many stresses which likely impact on their QOL. It is thus postulated that the QOL construct may exhibit a different structure for the population with sickle cell disease. SUBJECTS AND METHODS: The SF-36 v.2 was interviewer administered to the Jamaican Sickle Cell Disease Cohort Study participants ('Cohort' sample) and a random sample of adult sickle cell unit patients ('Main'sample). Demographic data were also collected on both groups. Both of the samples did not meet the five rule criteria for compliance with the original SF-36 component structure. Hence, principal components analysis was used to determine the component structure of the SF-36 in both groups. RESULTS: Three dimensions may underlie the SF-36 for both groups and these could be labelled 'Physical Health', 'Mental Health' and 'Role Limitations'. This solution accounted for 45.8% of the variability underlying the SF-36 in the 'Cohort'sample and 54.6% of the variability in the 'Main' sample. CONCLUSIONS: It concluded that within Jamaican samples of patients with sickle cell disease, the SF-36 has a component structure which is quite distinct from that initially proposed by its creators.


Assuntos
Anemia Falciforme/epidemiologia , Anemia Falciforme/psicologia , Qualidade de Vida/psicologia , Inquéritos e Questionários , Adulto , Anemia Falciforme/genética , Demografia , Feminino , Humanos , Jamaica/epidemiologia , Masculino
16.
West Indian Med J ; 56(6): 540-3, 2007 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-18646500

RESUMO

Intrathoracic extramedullary haematopoiesis is a rare entity encountered in patients with long standing anaemias such as thalassaemia and congenital spherocytosis. It is rare in patients with homozygous sickle cell disease; only 11 cases of intrathoracic and two cases of pelvic extramedullary haematopoiesis have been documented in the literature. We report the case of a 30-year old man with homozygous sickle cell disease with intrathoracic and pelvic extramedullary haematopoiesis, the first case to be documented from the Caribbean.


Assuntos
Anemia Falciforme/fisiopatologia , Medula Óssea/fisiologia , Hematopoese Extramedular/fisiologia , Adulto , Evolução Fatal , Humanos , Masculino , Ossos Pélvicos , Vértebras Torácicas
18.
West Indian Med J ; 54(3): 176-80, 2005 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-16209222

RESUMO

Clinical audits monitor the use of particular interventions, or the care received by patients, against agreed standards. Any departures from "best practice" can then be examined, and causes can be determined and acted upon. The Ministry of Health (MOH), Jamaica, has recently published standards of care for hypertension. The medical records of a convenience sample of 125 hypertensive patients being managed by five current family medicine residents in their respective primary care practices were audited Initial results showed limited adherence to the MOH recommended hypertension management guidelines. The same practices were re-audited after an interval of six months, during which time the physicians were sensitized to the results of the preliminary audit. Marked improvements were noted in the second audit. Assessment for co-risk factors for hypertension-related diseases improved: nutritional advice (33% to 74%), smoking and alcohol intake history (40% to 65%) and history taking of physical activity (30% to 47%). Assessment for target organ damage also improved: fundoscopy done (11% to 54%), foot examination done (30% to 58%) and yearly electrolytes done (28% to 62%). There are clear gaps between current practice and standards that exist internationally and locally for management of hypertension. The MOH needs to disseminate and educate general practitioners about the standards of care guidelines.


Assuntos
Medicina de Família e Comunidade/normas , Hipertensão/terapia , Auditoria Médica , Qualidade da Assistência à Saúde , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Fidelidade a Diretrizes , Humanos , Jamaica , Masculino , Pessoa de Meia-Idade , Fatores de Risco
20.
West Indian med. j ; 54(3): 176-180, Jun. 2005.
Artigo em Inglês | LILACS | ID: lil-417399

RESUMO

Clinical audits monitor the use of particular interventions, or the care received by patients, against agreed standards. Any departures from [quot ]best practice[quot ] can then be examined, and causes can be determined and acted upon. The Ministry of Health (MOH), Jamaica, has recently published standards of care for hypertension. The medical records of a convenience sample of 125 hypertensive patients being managed by five current family medicine residents in their respective primary care practices were audited Initial results showed limited adherence to the MOH recommended hypertension management guidelines. The same practices were re-audited after an interval of six months, during which time the physicians were sensitized to the results of the preliminary audit. Marked improvements were noted in the second audit. Assessment for co-risk factors for hypertension-related diseases improved: nutritional advice (33% to 74%), smoking and alcohol intake history (40% to 65%) and history taking of physical activity (30% to 47%). Assessment for target organ damage also improved: fundoscopy done (11% to 54%), foot examination done (30% to 58%) and yearly electrolytes done (28% to 62%). There are clear gaps between current practice and standards that exist internationally and locally for management of hypertension. The MOH needs to disseminate and educate general practitioners about the standards of care guidelines


Los auditores clínicos monitorean el uso de intervenciones particulares, o la atención recibida por los pacientes, a fin de verificar si se cumplen las normas establecidas. Cualquier desviación de "la práctica estándar" puede ser entonces analizada, determinándose de ese modo las causas, y empren-diéndose las correspondientes acciones sobre ellas. El Ministerio de Salud (MS) de Jamaica, ha publicado recientemente las normas del cuidado de la hipertensión. A las historias clínicas de una muestra de conveniencia de 125 pacientes hipertensos tratados por cinco residentes de medicina familiar en sus respectivas consultas de atención primaria, se les practicó una auditoría. Los resul-tados iniciales mostraron una correspondencia limitada con las pautas para el tratamiento de la hipertensión recomendadas por el MS. Las mismas prácticas fueron sometidas de nuevo a auditoría, luego de un intervalo de seis meses, durante el cual se sensibilizó a los médicos con los resultados de la auditoría preliminar. En la segunda auditoría se observaron mejorías considerables. Mejoró la evaluación de los factores de co-riesgo por enfermedades relacionadas con la hipertensión: consejo nutricional (33% a 74%), historia de hábito de fumar y consumo de alcohol (40% a 65%), confección de historia de la actividad física (30% a 47%). También mejoró la evaluación de daños dirigida a órganos predeterminados: fondoscopia realizada (11% a 54%), examen de pies realizado (30% a 58%) y electrólitos anuales hechos (28% a 62%). Evidentemente hay lagunas entre la práctica común y las normas existentes internacional y localmente para el tratamiento de hipertensión. El MS necesita diseminar y educar médicos generales versados en las normas de cuidado establecidas.


Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Auditoria Médica , Hipertensão/terapia , Medicina de Família e Comunidade/normas , Qualidade da Assistência à Saúde , Fatores de Risco , Fidelidade a Diretrizes , Jamaica
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