RESUMO
We studied 317 eyes, operated on for congenital glaucoma by Elliot, iridencleisis, goniotomy and trabeculotomy with a follow up of 5 to 35 years. Elliot and iridencleisis gave 30 to 50% intraocular pressure stabilisation and 60% bad visual results. Goniotomy gave without treatment 60% pressure stabilisation and 37% good visual results. Trabeculectomy gave 74% pressure stabilisation and 53% good visual results. Trabeculotomy gave the best results and can be considered as the most efficient operation in congenital glaucoma.
Assuntos
Glaucoma/cirurgia , Pré-Escolar , Estudos de Avaliação como Assunto , Feminino , Seguimentos , Glaucoma/congênito , Humanos , Lactente , Recém-Nascido , Masculino , Fatores de Tempo , Trabeculectomia , Acuidade VisualRESUMO
Leber's optic neuropathy is a maternally inherited disease. Its transmission does not correspond to Mendelian principles and two hypothesis about the role of cytoplasmic transmission are discussed. The role of a virus or a mutation mitochondrial DNA, maternally transmitted, are possible. However if not definite conclusion can be, actually, certified, there is a good hope to find a solution for this disease, in a near future.
Assuntos
Neuropatia Hereditária Motora e Sensorial/genética , Atrofias Ópticas Hereditárias/genética , DNA Mitocondrial , Humanos , Atrofias Ópticas Hereditárias/microbiologia , Viroses/genéticaRESUMO
We have studied among 192 patients affected by congenital glaucoma the long term efficacy of 4 interventions. Elliot's trophination, iridencleisis, goniotomy, trabeculotomy. Trabeculotomy gives the best results and is the most suitable intervention in congenital glaucoma.
Assuntos
Glaucoma/congênito , Criança , Estudos de Avaliação como Assunto , Feminino , Seguimentos , Glaucoma/cirurgia , Humanos , Masculino , Reoperação , TrabeculectomiaRESUMO
233 personal cases of leber's optic neuropathy have been analyzed by the authors in order to present clinical symptoms, evolution and genetic aspects. A group of 23 patients, in which 7 presented the disease and the others were asymptomatic members of families with the disease, was analyzed on evaluation of abnormalities of evoked visual responses; An other similar group, in repartition of subjects, was analyzed on frequency of cardiovascular abnormalities. The results have been analyzed and discussed about the role of predictive symptoms in diagnosis of the acute phase of the disease.
