Trichorhinophalangeal syndrome type 1 (Giedion syndrome): A case report with literature review.

INTRODUCTION AND OBJECTIVES: Trichorhinophalangeal syndrome (TRPS) is a rare multisystem disorder characterized by abnormalities in the hair (tricho), nose (rhino), and digits (phalangeal). A variety of nonspecific intraoral findings have been reported in the literature, including hypodontia, delayed tooth eruption, malocclusion, a high-arched palate, mandibular retrognathia, midface hypoplasia, and multiple impacted teeth. In addition, supernumerary teeth have been detected in several persons with TRPS, especially type 1. This report describes the clinical manifestations and dental management of a TRPS 1 patient with multiple impacted supernumerary and permanent teeth. PATIENT: A 15-year-old female patient visited our clinic with a known medical history of TRPS 1 with laceration of the tongue caused by teeth eruption in the palate. RESULTS: Radiographic images showed a total of 45 teeth: two deciduous, 32 permanent, and 11 supernumerary teeth. Six permanent teeth and 11 supernumerary teeth in the posterior quadrants were impacted. Four impacted third molars, supernumerary teeth, retained deciduous teeth, and impacted maxillary premolars were removed under general anaesthesia. DISCUSSION AND CONCLUSIONS: This case suggests that all patients with TRPS should undergo full clinical and radiographic oral examination and should be informed about the disease and the importance of dental counselling.

Evaluation of the quality of life and the satisfaction level after reconstruction with anterior iliac crest graft and implant-supported fixed prosthesis treatment.

PURPOSE: To evaluate oral health-related quality of life (OHRQoL) and satisfaction levels related to treatment in patients who have complete implant treatment and prosthetic rehabilitation after anterior iliac crest grafting. MATERIALS AND METHODS: Fifty-four patients (37 F, 17 M) with a total of 487 implants placed and implant-supported fixed prosthesis treatment completed were included in the study. OHIP-14OHIP-14 scale and satisfaction Likert scale questions were used to evaluate the OHRQoL and the satisfaction levels related to the treatment applied, respectively. To compare the outcomes, the significance test and the Mann-Whitney U-test were used. One-way analyses of variance and Kruskal-Wallis were used to assess the significance of differences among or between the groups. RESULTS: The quality of life (QoL) was higher, and the mean OHIP-14 scores were lower in women, older patients, and cases with a longer follow-up period, recorded as 13.6 ± 10.3 (p: 0.263), 12.9 ± 11.3 (p: 0.079), and 11.8 ± 9.6 (p: 0.015*), respectively. Moreover, satisfaction levels of the patients related to the treatment were 83.3%. CONCLUSIONS: The treatment of severely atrophic jaws with anterior iliac crest for the implant and prosthetic rehabilitation has a positive effect on the QoL. This effect has increased with time, and the satisfaction levels of the patients related to this procedure were high, and their expectations regarding this treatment were met at a high level.

The evaluation of stress on bone level and tissue level short implants: A Finite Element Analysis (FEA) study.

PURPOSE: This study aimed to evaluate the difference between the stress level and distribution around the BL and TL short implants, and their surrounding structures, using finite element analysis. METHODS: Two different study models were constructed: BL model and TL model. Two dental implant systems (ITI (Straumann, Waldenburg, Switzerland) and NTA Short) with a diameter of 4.1 mm and 4 mm and with a length of 6 mm were used in this study. In each model, implants were placed in the mandibular 1st molar region. The von Mises stress and maximum principal (tensile) and minimum principal (compressive) stresses were evaluated. RESULTS: The highest stress values recorded in the BL implants (von Mises: 342.77 MPa), in the peri­implant bone around the BL implants (maximum principal stress: 114.1 MPa), as a result of oblique loading, and overall stress values were found to be higher in the BL model. However, these measured values appeared to be low to cause a fracture, when considering the yield strengths of the materials and bone. CONCLUSIONS: The stress values were higher in the BL model, but not high enough to cause failure. Short implants could be an effective method of treatment for patients unsuitable for advanced surgical techniques.

Evaluation of the effects of locally applied rosuvastatin on bone formation in a three-dimensional reconstruction rabbit xenograft model

Background/aim: Guided bone regeneration (GBR) is commonly performed to repair bone defects, and rigid occlusive titanium barriers play a vital role in bone formation in regions with no prior bone tissue. The statin, rosuvastatin (RSV), strongly affects bone apposition when applied locally. Here, we aimed to evaluate the anabolic effects of locally applied RSV with a xenograft placed on rabbit calvaria. Materials and methods: Two rigid occlusive titanium caps were used in 16 rabbits after decorticating the calvarial bone. In the control group, the area under the cap was filled with a xenograft, while in the RSV group, a xenograft in combination with RSV (1 mg) was used. In both groups, at 6 and 12 weeks, new bone, residual graft, soft tissue areas, and histological and radiological bone volume were evaluated. Results: At 12 weeks, histologically, the RSV group exhibited superior new bone proportion values, and radiologically, new bone and total bone volume in the RSV group were significantly higher than in the control group (p < 0.05); there were no significant differences at 6 weeks (p > 0.05). Conclusion: According to our results, RSV applied locally under a titanium barrier on an area to be repaired with bone grafts increases new bone and total bone volume.

Complications Associated With Anterior Iliac Bone Grafting for the Reconstruction of Dentoalveolar Defects.

The aim of this study is to evaluate donor- and recipient-site complications of iliac bone grafting for the reconstruction of atrophic jaws.Our study includes 86 consecutive patients with atrophic jaws who underwent iliac bone grafting surgery. At the donor site, hematoma, infection, paresthesia, chronic pain, prolonged gait disturbance, fracture of the ilium, and esthetic concerns; at the recipient site, hematoma, infection, prolonged pain, graft exposure, graft loss, and loss of the implants were evaluated.Grafting was successfully performed in all patients. The mean follow-up period was 35 months. Prolonged gait disturbance (20.9%) and paresthesia (9.3%) were the most frequently observed donor-site complications. At the recipient site, hematoma (8.1%), infection (12.8%), prolonged pain (11.6%), partial graft exposure (33.7%), total graft exposure (7%), partial graft loss (17.4%), and total graft loss (5.8%) were observed.Reconstruction of atrophic jaws can be achieved successfully with iliac bone grafting. However, there are possible donor- and recipient-site complications that have to be taken into consideration.

Comparison between peri-implant bone level changes of implants placed during and 3 months after iliac bone grafting.

OBJECTIVE: The aim of this study was to compare the peri-implant bone level changes of implants placed during and 3 months after bone grafting from the iliac crest. STUDY DESIGN: A total of 103 implants were placed: 42 during the grafting and 61 at 3 months after the grafting procedure. All patients were grafted with iliac bone from the anterosuperior iliac crest. Bone resorption was evaluated with cone beam computed tomography in all patients at their last control visit. Periodontal health was assessed via the gingival and plaque indices and pocket depths around the dental implants. RESULTS: Mean bone resorption values at the buccal, lingual, mesial, and distal sides of the implants were 1.08 mm, 0.36 mm, 0.30 mm, and 0.25 mm, respectively, in the delayed group, and 1.87 mm, 1.25 mm, 0.92 mm, and 1.23 mm, respectively, in the simultaneous group; the differences between the groups were significant. There were no significant between-group differences in the gingival or plaque indices or pocket depths. The mean follow-up period was 29 months. CONCLUSIONS: For reconstructing atrophic jaws, bone grafting from the iliac crest and implant placement after 3 months is a reliable technique with a high success rate and less bone resorption.