[Tuberculous periodontitis]. / Tuberkulëznyi periodontit.

Peridental foci of infection (PFI) in periodontitis in 113 patients with pulmonary tuberculosis were evaluated clinico-morphologically with regard to mycobacterial populations. Vegetation in PFI of bacterial, bacterial and L-form M. tuberculosis (37.2%) was associated with clinically inapparent periodontitis symptoms, formation of large and middle-size PFI with destruction and foci of productive tuberculous inflammation. Persistent L-forms of M. tuberculosis (59.3%) brought out a symptomless periodontitis with small and middle-size PFI, manifest immune or minor tuberculous inflammation, reparative processes. The findings suggest that PFI in tuberculous patients' periodontitis is a form of extrapulmonary tuberculosis.

[Cellular reactions in contamination with various types of Mycobacterium in experimental study]. / Kletochnye reaktsii pri zarazhenii razlichnymi vidami mikobakterii v éksperimente.

Characteristics of specific inflammation induced by intradental challenge with mycobacteria (MB) were studied cytologically and bacterioscopically. Mycobacterium tuberculosis hominis and bovis, BCG, atypical M. fortuitum in the 5th dilution by turbidity standard were administered into the root canals of a tooth and pulp cavities of 16 mongrel dogs (body mass 13-16 kg, age 1-4 years). Investigation of the dogs' organs and paradental tissues revealed that MB underwent L-transformation the speed of which depended on the species. Cellular reactions were also related to the agent species and form of vegetation. Cytobacterioscopic tests are proposed as additional diagnostic means and to validate therapeutic policy.

[Mycobacteria in the development of periodontal foci of infection]. / Mikobakterii v razvitii okolozubnykh ochagov infektsii.

A total of 162 samples of material from the periodontal foci of infection were examined microbiologically and morphologically to detect mycobacteria and their biologically changed variants. The regularities of the pathologic process development in periodontal tissues of subjects without tuberculosis were found to fully conform to the current concept of a latent tuberculous infection. The periodontal foci of infection may be regarded as reservoirs of persistent mycobacteria, whose main form, L variant, was detected in 71.6% of cases. Clinical and morphologic manifestations of periodontitis depend on the stability of the persistent mycobacteria L forms.

[Intra-dental route of experimental tuberculosis infection]. / Intradental'nyi put' zarazheniia tuberkulezom v éksperimente.

A total of 13 dogs weighing 13-15 kg were infected by intra-dental route with the tuberculosis mycobacterium strain H37R in a dose of 0.5 ml in the 5th dilution according to a turbidity standard. Two dogs were given intravenously the same dose of tuberculosis mycobacteria and they formed a control group. The observation varied from 10 days to 5 months. It was found tuberculosis development in intradental contamination could be attended by generalized specific affection of the viscera and development of a "minor" tuberculosis inflammation in the peridental tissues.