Tumor de células granulares cutáneo: revisión en la edad pediátrica / Cutaneous granular cell tumor: a review of the childhood cases

El tumor de células granulares cutáneo (TCGC) constituye una neoplasia benigna que puede presentarse en la infancia como un nódulo asintomático. La malignización no se ha descrito en niños, pero su aspecto clínico inespecífico obliga a realizar un diagnóstico diferencial con otras lesiones cutáneas comunes en la infancia junto a la realización de un estudio histológico confirmatorio. Cuando se presentan lesiones múltiples se ha descrito su asociación a numerosos defectos corporales y enfermedades sistémicas como el síndrome de Noonan o la neurofibromatosis, por lo que su conocimiento puede ser un marcador de riesgo que permita al dermatólogo y al pediatra descubrir otras anomalías asociadas. Realizamos una revisión del TCGC en la infancia (AU)

The cutaneous granular cell tumor (CGCT) is a benign neoplasm ocasionally present in children as an asymptomatic nodule. Malignant CGCT have not been described in childhood by now, but the unspecific clinical appearence of the tumor induce to a wide differential diagnoses and a biopsy ismandatory. When multiple CGCT are developed, dermatologist and pediatrician must perform a complete physical examination to rule out the presence of the systemic defects previously reported in association with CGCT as Noonan syndrome and neurofibromatosis. We review the literature on this topic (AU)

Primary pure intratesticular fibrosarcoma.

Testicular sarcoma appears to be a rare stromal tumor usually of indolent course with potential for distant metastases. A pure primary intratesticular fibrosarcoma in a 71-year-old male is presented. By the time the tumor became evident metastases had already occurred widely. The course was rapidly fatal. A review of the literature yielded only one case reported previously. The present case illustrates that pure fibrosarcoma occurs occasionally as a stromal tumor and may be associated with a dismal prognosis. The diagnosis of pure fibrosarcoma should be made only after extensive sampling of the testicular tumor to rule out an associated germ cell component. The differential diagnosis also includes the fibroma of gonadal stroma origin and the unclassified sex cord-stromal tumor with a predominance of spindle cells.

Pilonidal sinus of the penis. A report of two cases, one of them associated with actinomycosis.

Pilonidal sinus is a long-standing chronic inflammatory condition which occurs most commonly in the sacrococcygeal area and it is rare in the penis. Two cases of penile pilonidal sinus in patients aged 25 and 28 years are reported and the literature is reviewed. The lesion is acquired and has to be distinguished from balanoposthitis, epidermal cyst and carcinoma. For pilonidal sinus to occur at this site, it is hypothesized that the coronal sulcus acts as a cleft where hair may accumulate and be driven into the shaft and prepuce by the natural movement between these two surfaces. One of our cases was associated with actinomycosis. Actinomycosis associated with pilonidal sinus of the penis is extremely rare and there are only two previous reports. It is suggested that pilonidal sinus may have been predisposed to the infection with the actinomyces organisms. Information stating that penile pilonidal sinus and actinomycosis may occur simultaneously is necessary to accomplish an early diagnosis.