Simulation study on the conversion between CT and CBCT dose quantities via the effective dose.

In recent years, cone-beam computed tomography (CBCT) has been used in many imaging tasks traditionally performed by computed tomography (CT). This has created challenges for dosimetry, as the dose quantities in CBCT and CT, i.e. the dose-area product (DAP) and dose-length product (DLP), are not mutually convertible. Convertibility would be desirable to compare doses in similar clinical studies performed using CT or CBCT and ultimately for the application of diagnostic reference levels (DRLs). In this work, the conversion of the DAP into the DLP and vice versa via the effective doseEis investigated with the aim of finding common diagnostic reference levels. The dose calculation was performed using Monte Carlo simulations for scan regions with imaging tasks, which can be carried out either with CT or CBCT scanners. Four regions in the head and four in the trunk were chosen. The calculations resulted in conversion coefficientsk=DAPDLPof 30(4) cm for the cranium, 22(4) cm for the facial bones, 24(2) cm for the paranasal sinuses, 18(2) cm for the cervical spine, 78(12) cm for the thorax, 85(13) cm for the upper abdomen, 57(6) cm for the lumbar spine and 70(12) cm for the pelvis.

Catalog of x-ray spectra of Mo-, Rh-, and W-anode-based x-ray tubes from 10 to 50 kV.

This work presents a comprehensive catalog of x-ray spectra measured from x-ray tubes with tungsten, molybdenum, and rhodium anodes generated at tube potentials between 10 and 50 kV in steps of 1 kV. They can serve as an input for dose calculations, image quality calculations, investigations of detector features, and validations of computational spectral models, among other things. The measurements are performed by means of a high-purity germanium detector-based spectrometer 1 m from the x-ray sources without any added filtration. The x-ray tubes are characterized by thin beryllium exit windows (0.15-4 mm); thus, for energies above 15 keV, the spectra recorded can be considered approximately unfiltered. This allows potential users of the catalog to computationally add any filter to the spectra in order to create special radiation qualities of their choice. To validate this option, a small number of spectra are recorded with filter materials in place whose purity and thickness are known with high precision. These spectra are compared to the corresponding spectra from the catalog obtained by means of computationally added filters. The two types of spectra agree extremely well. Several typical mammographic radiation qualities are selected to compare the spectra obtained from the catalog presented here with corresponding spectra obtained from other catalogs published by Booneet al(1997Med. Phys.241863-74) and Hernandezet al(2017Med. Phys.442148-60). In contrast to the work presented here, those spectra rely partly or fully on calculations. A quantitative comparison is made by means of typical x-ray quality descriptors such as the mean energy and the first and second half-value layer. The results obtained from the Boone catalog match those of the current catalog sufficiently well for the Mo- and Rh-anode-based spectra. However, significant differences up to 10 times the estimated uncertainties are found for the quality descriptors evaluated from the spectra of Hernandezet aland the W-anode based spectra of Booneet al.

Monte Carlo and water calorimetric determination of kilovoltage beam radiotherapy ionization chamber correction factors.

The in-phantom calibration method for radiotherapy kilovoltage x-ray beams requires ionization chamber correction factors. The overall ionization chamber correction factor accounts for changes in the chamber response due to the displacement of water by the chamber cavity and wall, the presence of the stem and the change in incident photon energy and angular distribution in the phantom to that in air. A waterproof sheath, if required, is accounted for in a sheath correction factor. The aim of this study is to determine chamber correction factors through Monte Carlo (MC) simulations and water calorimetry measurements. Correction factors are determined for the PTW TM30013, NE2571, IBA FC65-G, IBA FC65-P and Exradin A12 ionization chambers. They are compared to experimental values obtained at the German national metrology institute Physikalisch-Technische Bundesanstalt (PTB) with their water calorimetry-based absorbed dose to water primary standard and at other national metrological institutes. An uncertainty analysis considers the contributions to the uncertainty on the chamber correction factors from the field size, photon cross sections, photon fluence spectra and chamber wall and central electrode dimensions. The MC calculated chamber correction factors are within 2.2% of unity with a standard uncertainty of 0.3%. For the 50 kV and 100 - 140 kV radiation beam qualities, the calculated correction factors deviate from the measured correction factors (with a standard uncertainty of 1%) by up to 2.6%. The calculated chamber correction factors for the PTW TM30013 and Exradin A12 are consistent with those derived from the BIPM kilovoltage primary standard. The inconsistencies between the calculated and experimental chamber correction factors indicate the need to further investigate the accuracy of kilovoltage absorbed dose to water primary standards and the use of MC simulations to determine kilovoltage beam chamber correction factors.

Comparison of pencil-type ionization chamber calibration results and methods between dosimetry laboratories.

A comparison of calibration results and procedures in terms of air kerma length product, PKL, and air kerma, K, was conducted between eight dosimetry laboratories. A pencil-type ionization chamber (IC), generally used for computed tomography dose measurements, was calibrated according to three calibration methods, while its residual signal and other characteristics (sensitivity profile, active length) were assessed. The results showed that the "partial irradiation method" is the preferred method for the pencil-type IC calibration in terms of PKL and it could be applied by the calibration laboratories successfully. Most of the participating laboratories achieved high level of agreement (>99%) for both dosimetry quantities (PKL and K). Estimated relative standard uncertainties of comparison results vary among laboratories from 0.34% to 2.32% depending on the quantity, beam quality and calibration method applied. Detailed analysis of the assigned uncertainties have been presented and discussed.

Non-invasive experimental determination of a CT source model.

Non-invasive methods to determine equivalent X-ray source models of a CT scanner are presented. A high-precision technique called TRIC ("Time Resolved Integrated Charge") was developed and used to characterize the bow tie filters (BT) of the CT scanner installed at Physikalisch-Technische Bundesanstalt (PTB). Aluminum (Al) and polymethyl methacrylate (PMMA) equivalent thicknesses of the BT filters at all tube high voltages were evaluated, assuming that those consist of only one material. Thereby two different dose probes were used, a solid state detector and an ionization chamber, the former characterized by a significant and the latter by an almost negligible energy dependence of the air kerma response. A method was developed to correct for the energy dependence of the solid state dose probe. Next, a two-component material was assumed and equivalent BT filters were evaluated. The latter method was also applied using the known real BT filter materials and compared with the shape of the real BT filters. Finally, the results obtained by the TRIC method were compared with those obtained by using the so-called COBRA method ("Characterization Of Bow tie Relative Attenuation"), the latter being more suitable for measurements in a clinical environment.