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Food Chem ; 278: 424-433, 2019 Apr 25.
Artigo em Inglês | MEDLINE | ID: mdl-30583393

RESUMO

Centaurium erythraea Rafn is a food flavouring used in both food and beverage industries. Despite the existence of some works on this species, only few focus their attention on its common form of consumption (infusion). Thus, we intended to explore the chemical composition and the biological properties of infusions from C. erythraea aerial parts. Phenolic compounds were identified by HPLC-DAD-ESI/MSn, twenty-two flavonoid derivatives being reported for the first time. Concerning to the biological potential, the best scavenging activity was observed for the superoxide anion radical. Moreover, this extract revealed to have some effect on the inhibition of 5-lipoxygenase, no cytotoxicity against RAW 264.7 macrophage cells line, and a weak potential to decrease the nitric oxide levels in this cell system. The results suggest that C. erythraea aerial parts could be valuable sources of health benefits compounds, contributing to its valorisation and its further application in functional foods.


Assuntos
Centaurium/química , Fenóis/análise , Extratos Vegetais/química , Animais , Sobrevivência Celular/efeitos dos fármacos , Centaurium/metabolismo , Cromatografia Líquida de Alta Pressão , Flavonoides/química , Limite de Detecção , Camundongos , Óxido Nítrico/metabolismo , Fenóis/farmacologia , Componentes Aéreos da Planta/química , Componentes Aéreos da Planta/metabolismo , Células RAW 264.7 , Espectrometria de Massas por Ionização por Electrospray , Superóxidos/química , Superóxidos/farmacologia
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