[Diagnosis of ischemic heart disease in patients with bronchial asthma caused by cytotoxic dust].

To reveal latent IHD, the authors performed stress testing (veloergometry and transesophageal cardiac electric stimulation) in 63 patients with chronic obstructive dust bronchitis (CODB) and CODB complicated with bronchial asthma varying in severity. Latent IHD was diagnosed in 8% of the patients. Higher tolerance of physical exertion was seen in all groups of the patients, except for those with severe bronchial asthma--who had lower and medium tolerance. Patients with positive veloergometry test performed medium and high level of exertion.

[Biochemical parameters in evaluation of liver functional state in workers engaged into general mechanical rubber goods production].

Findings are that lipid peroxidation and antioxidant system are the most sensitive processes--that was proved by malonic dialdehyde accumulation, higher ceruloplasmin and lower catalase levels.

[Flow volume curve evaluation of respiratory function in wolfram-molybdenum miners]. / Otsenka funktsii vneshnego dykhaniia po petle potok-ob"em u rabochikh vol'frammolibdenovogo rudnika.

The authors studied respiratory function in workers of wolfram-molybdenum mine where dust contains nearly 75% of silicon dioxide and considerable amounts of metals. The examinees were those with I stage silicosis and with silicosis complicated by chronic obstructive bronchitis. The respiratory disorders appeared most severe in association of the diseases.

[Comparative analysis of respiratory function in miners suffering from anthracosilicosis and silicosis]. / Sravnitel'nyi analiz funktsii vneshnego dykhaniia u gornorabochikh s antrakosilikozom i silikozom.

The authors revealed differences in pulmonary volumes, bronchial patency of bronchi at various levels, integral time of air transit in individuals having early anthracosilicosis and silicosis signs vs in healthy miners. During stage 1 of anthracosilicosis and silicosis respiratory function progressively deteriorates and demonstrates moderate disorders. When compared to anthracosilicosis ones, patients having polymetallic dust silicosis showed more significant decrease of the studied parameters.

[Metabolism of serum phospholipids in coal miners]. / Metabolizm fosfolipidov plazmy krovi u shakhterov-ugol'shchikov.

The studies covered metabolism of serum phospholipids during lipids peroxidation and hydrolysis by phospholipase A2. Metabolism of serum phospholipids appeared to depend on duration of exposure to mine dust and on coal pneumoconiosis stage. Lipids peroxidation becomes activated after 20 and more years of service, intensifies with anthracosilicosis development on background of higher catalase activity that is low on early stages of the disease. Activity of phospholi pase A2 increases with pulmonary fibrosis progression.

[The body's hormonal balance in miners at the coal mines]. / Gormonal'nyi balans organizma u gornorabochikh ugol'nykh shakht.

The hormonal background of coal-pit miners was studied by radioimmunoassay method. It was determined, that adaptation to coal-dust influence proceeds by protective-compensatory increasing of cortisol, thyroid hormones and insulin levels. When a functional reserves of endocrine glands exhausted, the adaptation breaks down and pneumoconiosis may arise.

[Long-term effect of coal and rock dust on the changes of some biochemical parameters in miners]. / Izmenenie nekotorykh biokhimicheskikh pokazatelei u shakhterov pri dlitelnom vozdeistvii ugolno-porodnoi pyli.

The study revealed those changes in connective tissue components and validity of alveolar macrophages in bronchial lavage, which were in correlation with duration and severity of exposure to coal and rock dust. The data proved that roentgenologio changes in the lungs are preceded by changed quantity of viable alveolar cells, higher content of hexauronic acids and hexoses associated with proteins. The stated biochemical tests could be applied to early diagnosis in individuals prone to pneumoconiosis.