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1.
JDR Clin Trans Res ; : 23800844241235615, 2024 Apr 16.
Artigo em Inglês | MEDLINE | ID: mdl-38623874

RESUMO

INTRODUCTION: Despite substantial research and provision of dental care, significant morbidity remains for children's oral health. Guided by social practice theory (SPT), this research moves away from the often-ineffective focus on changing individual behavior to rethinking the centrality of the social world in promoting or undermining oral health outcomes. We define social practice as a routinized relational activity linking and integrating certain elements (competence, materials, and meanings) into the performance of a practice that is reproduced across time and space. OBJECTIVE: To investigate oral health in preschool children in Perth, Western Australia, using social practice theory. METHODS: With no definitive methodology for investigating SPT, we chose focused ethnography as a problem-focused, context-specific approach using mainly interviews to investigate participants' experience caring for their children's oral health. The focus of analysis was the practice of oral health care, not individual behavior, where themes identified from participants' transcripts were organized into categories of elements and performance. RESULTS: Eleven parents, all of whom were married or partnered, were interviewed in 2021. Findings identified social practices relevant to oral health within parenting and family relations linked to routine daily activities, including shopping, consumption of food and beverages, and toothbrushing. Oral health literacy was reflected in integrating competence, materials, and meanings into performing oral health care, notably preferences for children to drink water over sugary beverages and information often being sourced from social media and mothers' groups rather than health providers. CONCLUSION: Focusing on social practices as the unit of analysis offers a more layered understanding of elements in young children's oral health care that can indicate where the problem may lie. Findings provide an opportunity to consider future research and policy directions in children's oral health. KNOWLEDGE TRANSFER STATEMENT: Examining social practices related to young children's oral health care identifies parents/carers' knowledge about, for example, toothbrushing, the resources required, and why toothbrushing is important. Analyzing these separate elements can reveal both enablers and barriers to oral health care. This provides researchers, clinicians and policymakers an opportunity to focus on not changing individual behavior but understanding how social context impacts parents/carers' capacity to make optimum decisions around young children's oral health.

2.
Artigo em Inglês | MEDLINE | ID: mdl-38373221

RESUMO

OBJECTIVES: Adults who have learning disabilities are a vulnerable group, little is known about their oral health and how this affects their quality of life. The aims of this secondary analysis of data from the 2009 Adult Dental Health Survey (ADHS) were to describe the oral health status of adults with learning disabilities, determine if severity of learning disability is associated with oral health and identify some of the methodological complexities of working with this population. The survey yields the most recent representative data on the oral health of adults with learning disabilities in England and importantly, contains information about oral health related quality of life (OHRQoL). BASIC RESEARCH DESIGN: Secondary analysis of data from a supplemental survey of adults with learning disabilities collected alongside the 2009 ADHS. PARTICIPANTS: 607 participants with a diagnosed learning disability aged 18 years and over. RESULTS: Adults with learning disabilities had similar levels of active dental caries, fewer natural teeth, and fewer fillings than comparable participants from the general population. Self-reported oral and general health were worse for adults with learning disabilities than the general population. Possible associations between the severity of learning disability and the numbers of decayed, missing or filled teeth were identified. However, large amounts of missing data limited the analysis. CONCLUSIONS: There are important questions relating to the accessibility of existing self-reported oral health questionnaires and the reliability of proxy-reported questions about OHRQoL that should be addressed to give a fuller picture of the oral health of adults with learning disabilities.

3.
Gerodontology ; 2024 Jan 21.
Artigo em Inglês | MEDLINE | ID: mdl-38247018

RESUMO

OBJECTIVE: Examine the literature on the experiences of living with removable dentures (complete or partial) to identify any gaps and provide a map for future research. BACKGROUND: Increasing proportions of society are living partially dentate with some form of restoration, including removable dentures. Previous studies have reported on the location, materials and usage of these prostheses, along with effects on oral-health-related quality of life (OHRQoL). However, less is known about experiences with removable dentures from a patient-centred perspective. METHODS: A scoping review of the qualitative literature was undertaken using the framework of Arksey and O'Malley, updated by Levac et al. Literature searches were carried out using Medline and Web of Science. Papers were screened by title and abstract using inclusion and exclusion criteria. Remaining papers were read in full and excluded if they did not meet the required criteria. Nine papers were included in the final review. FINDINGS: Key themes from these papers were: impact of tooth loss and living without teeth, and its impacts in relation to social position, appearance, confidence and function (chewing and speaking); social norms and tooth loss, including attitudes to tooth retention and treatment costs, and changes in intergenerational norms towards dentures; expectations of treatment, including patients being more involved in decision making, viewing the denture as a "gift" and dentures helping to achieve "an ideal"; living with a removable denture (complete or partial), including patient preparedness for a denture, adaptation and impacts on activities and participation; and the dentist-patient relationship, including issues with information and communication, and differing priorities between patients and dentists. CONCLUSION: Little qualitative research exists on experiences of living with a removable denture. Existing literature demonstrates the importance of dispersed activities in differing social, spatial and temporal contexts when wearing removable dentures. Focusing on processes of positive adaptation to dentures and OHRQoL, rather than deficits, is also required to fully understand patients' experiences. Additionally, more complex technological advances may not always be in the best interest of every patient.

4.
J Clin Periodontol ; 51(1): 33-42, 2024 01.
Artigo em Inglês | MEDLINE | ID: mdl-37735867

RESUMO

AIM: To develop and validate a new health-related quality of life measure to capture a wide range of gum-related impacts. MATERIALS AND METHODS: The measure was developed using a multi-stage approach and a theoretical model. Development involved semi-structured interviews, pilot testing, cross-sectional analysis among a general population (n = 152) to assess psychometric properties and test-retest reliability among a subsample (n = 27). RESULTS: Psychometric analysis supports the validity and reliability of the measure's impact scale. The measure has excellent internal reliability (nearly all item-total correlations above .4; Cronbach's alpha between .84 and .91 for subscales), with test-retest reliability also performing well (Intra-class correlation coefficient [ICC] of .91-.97 for subscales). Good content validity (indicated by large standard deviations for item and total scores) and construct validity (correlations of .54-.73 with global gum health rating for subscales, all p < .05) were also observed. Qualitative and quantitative data indicate that people with gum health-related symptoms experience different degrees of discomfort and impacts caused by their condition. CONCLUSIONS: The gum health experience questionnaire holds substantial promise as a measure of gum-related quality of life in people across the gum health-disease continuum. Further face validity, refining and reducing the number of items and longitudinal studies to test evaluative properties are required before the measure can be used with confidence.


Assuntos
Doenças da Gengiva , Qualidade de Vida , Humanos , Reprodutibilidade dos Testes , Psicometria , Estudos Transversais , Inquéritos e Questionários
5.
BMC Oral Health ; 22(1): 512, 2022 11 18.
Artigo em Inglês | MEDLINE | ID: mdl-36401324

RESUMO

BACKGROUND: There has been a lack of qualitative work investigating the effects of the wide range of gum-related symptoms, and the perceived everyday impacts associated with these including on quality of life. While periodontal disease has been shown to have significant effects on quality of life, fewer studies have researched the perceived impacts of gingivitis and symptoms from across the entire gum health-disease continuum, despite evidence that these can also negatively affect quality of life. The aim of this study was to investigate perceived everyday impacts and explore the subjective experiences of adults with a variety of symptoms from across the self-reported gum health-disease continuum, and how these may affect quality of life. METHODS: Participants were recruited at a large UK University using purposive sampling, for self-reported symptoms ranging from mild gingivitis to severe periodontal disease. Semi-structured interviews gathered details on symptom history, changes occurring over time and associated beliefs, as well as perceived impacts on everyday life, and links between these experiences and identity. Interviews were analysed using framework analysis based on the Wilson and Cleary health-related quality of life model. RESULTS: Twenty-seven participants were recruited - 15 with symptoms of gingivitis, 12 with more severe periodontal symptoms. Prominent themes included description of symptoms, changes in daily life, social impacts, psychological impacts, identity, and overall impacts and quality of life. Differences were noted in severity, extent and frequency of symptoms and participant experiences, with greater perceived impacts often felt by those with periodontal disease. However, participants from across the gum health-disease continuum often expressed similar experiences and concerns. CONCLUSION: Findings demonstrate the range of experiences from participants with a variety of gum-related symptoms; notably, gingivitis was reported to have a range of perceived impacts on quality of life alongside those reported by periodontal disease sufferers. Future work should look to include symptoms from across the entire gum health-disease continuum when considering quality of life, as well as considering a more patient-centred approach which could be valuable in both clinical and research settings.


Assuntos
Gengivite , Doenças Periodontais , Humanos , Adulto , Qualidade de Vida/psicologia
6.
JDR Clin Trans Res ; 7(3): 256-266, 2022 07.
Artigo em Inglês | MEDLINE | ID: mdl-34027746

RESUMO

INTRODUCTION: Patients' decisions to undergo major surgery such as orthognathic treatment are not just about how the decision is made but what influences the decision. OBJECTIVES: The primary objective of the study was to identify the key processes involved in patients' experience of decision making for orthognathic treatment. METHODS: This study reports some of the findings of a larger grounded theory study. Data were collected through face-to-face interviews of patients who were seen for orthognathic treatment at a teaching hospital in the United Kingdom. Twenty-two participants were recruited (age range 18-66 y), of whom 12 (male = 2, female = 10) were 6 to 8 wk postsurgery, 6 (male = 2, female = 4) were in the decision-making stage, and 4 (male = 0, female = 4) were 1 to 2 y postsurgery. Additional data were also collected from online blogs and forums on jaw surgery. The data analysis stages of grounded theory methodology were undertaken, including open and selective coding. RESULTS: The study identified the central role of dental care professionals (DCPs) in several underlying processes associated with decision making, including legitimating, mediating, scheduling, projecting, and supporting patients' decisions. Six categories were related to key aspects of decision making. These were awareness about their underlying dentofacial problems and treatment options available, the information available about the treatment, the temporality of when surgery would be undertaken, the motivations and expectation of patients, social support, and fear of the surgery, hospitalization, and potentially disliking their new face. CONCLUSION: The decision-making process for orthognathic treatment is complex, multifactorial, and heavily influenced by the role of DCPs in patient care. Understanding the magnitude of this role will enable DCPs to more clearly participate in improving patients' decision-making process. The findings of this study can inform future quantitative studies. KNOWLEDGE TRANSFER STATEMENT: The results of this study can be used both for informing clinical practice around enabling decision making for orthognathic treatment and also for designing future research. The findings can better inform clinicians about the importance of their role in the patients' decision-making process for orthognathic treatment and the means to improve the patient experience. It is suggested that further research could be conducted to measure some of the key constructs identified within our grounded theory and assess how these change during the treatment process.


Assuntos
Cirurgia Ortognática , Procedimentos Cirúrgicos Ortognáticos , Adolescente , Adulto , Idoso , Tomada de Decisões , Feminino , Teoria Fundamentada , Humanos , Masculino , Pessoa de Meia-Idade , Reino Unido , Adulto Jovem
7.
Health Place ; 71: 102657, 2021 09.
Artigo em Inglês | MEDLINE | ID: mdl-34543838

RESUMO

This research used proof of concept agent-based models to test various theoretical mechanisms by which neighbourhoods may influence tooth decay in adults. Theoretical pathways were constructed using existing literature and tested in two study areas in Sheffield, UK. The models found a pathway between shops and sugar consumption had the most influence on adult tooth decay scores, revealing that similar mechanisms influence this outcome in different populations. This highlighted the importance of the interactions between neighbourhood features and individual level variables in influencing outcomes in tooth decay. Further work is required to improve the accuracy and reliability of the models.


Assuntos
Saúde Bucal , Características de Residência , Adulto , Humanos , Reprodutibilidade dos Testes , Fatores Socioeconômicos , Análise de Sistemas
8.
Community Dent Health ; 38(2): 142-149, 2021 May 28.
Artigo em Inglês | MEDLINE | ID: mdl-33769723

RESUMO

This article analyses the underrepresentation of racialised minorities across the three stages of the dental workforce pipeline through the critical lens of power. The reformist view of power was used, which focuses on concealment caused by systemic biases. We observed adequate representation of racialised minorities in the first two stages of the pipeline; entry to dental schools and completion of dental education. However, the categorisation of diverse groups into a single 'BAME' category conceals the underrepresentation of Black people and those who experience intersectional forms of discrimination rooted in race, gender and class. We observed all racialised minorities to be underrepresented in the third stage of the pipeline; career development and progression. The data suggest that institutional processes are more likely to recruit and promote White1 people, and racialised minorities are more likely to be exposed to bullying and inequitable disciplinary processes. Consistently across dental institutions, as the level of seniority increases, the representation of racialised minorities decreases. Thus, senior decision-making and agenda-setting spaces in UK dentistry are overwhelmingly White. Multiple actions are suggested; including collation of comprehensive, inclusive data, widening participation and representation initiatives to help re-distribute the power dynamics towards racialised minorities and ensure equality of representation across the dental pipeline, including in senior spaces. We hope this will work towards putting some of the systemic problems that we see in dentistry; such as differential staff and student experiences, inequitable recruitment, promotions and disciplinary proceedings, and colonial dental curricula and research on the institutional agenda.


Assuntos
População Negra , Grupos Minoritários , Humanos , Reino Unido , População Branca , Recursos Humanos
9.
Sci Rep ; 11(1): 1718, 2021 01 18.
Artigo em Inglês | MEDLINE | ID: mdl-33462294

RESUMO

Neutrophils and neutrophil extracellular traps (NETs) have been shown to be involved in coagulation. However, the interactions between neutrophils or NETs and fibrin(ogen) in clots, and the mechanisms behind these interactions are not yet fully understood. In this in vitro study, the role of neutrophils or NETs on clot structure, formation and dissolution was studied with a combination of confocal microscopy, turbidity and permeation experiments. Factor (F)XII, FXI and FVII-deficient plasmas were used to investigate which factors may be involved in the procoagulant effects. We found both neutrophils and NETs promote clotting in plasma without the addition of other coagulation triggers, but not in purified fibrinogen, indicating that other factors mediate the interaction. The procoagulant effects of neutrophils and NETs were also observed in FXII- and FVII-deficient plasma. In FXI-deficient plasma, only the procoagulant effects of NETs were observed, but not of neutrophils. NETs increased the density of clots, particularly in the vicinity of the NETs, while neutrophils-induced clots were less stable and more porous. In conclusion, NETs accelerate clotting and contribute to the formation of a denser, more lysis resistant clot architecture. Neutrophils, or their released mediators, may induce clotting in a different manner to NETs, mediated by FXI.


Assuntos
Coagulação Sanguínea , Armadilhas Extracelulares/metabolismo , Fator XI/metabolismo , Neutrófilos/metabolismo , Coagulação Sanguínea/efeitos dos fármacos , Diferenciação Celular , Linhagem Celular Tumoral , Meios de Cultura/química , Meios de Cultura/farmacologia , Fibrina/química , Humanos , Neutrófilos/citologia , Receptores de IgG/metabolismo , Trombina/farmacologia
10.
Community Dent Health ; 37(3): 174-179, 2020 Aug 31.
Artigo em Inglês | MEDLINE | ID: mdl-32212433

RESUMO

OBJECTIVES: Toothwear may impact on an individual's everyday life, yet there is little research investigating the association between toothwear and oral health related quality of life (OHRQoL). The aim of the present study was to investigate the association between toothwear and OHRQoL in adults in the United Kingdom. BASIC RESEARCH DESIGN: This study involved secondary analysis of data from 5187 participants with toothwear in the Adult Dental Health Survey conducted in 2009. Toothwear was assessed using Smith and Knight criteria and the Basic Erosive Wear Index and classified as mild, moderate and severe. MAIN OUTCOME MEASURES: Correlation analyses were carried out between OHIP-14 total scores and toothwear type. Regression analyses investigated the association between toothwear and OHRQoL adjusting for demographic variables. RESULTS: There was a significant association between toothwear and OHRQoL, with more severe toothwear associated with greater oral health impact on daily life. The association between erosive toothwear and OHRQoL was significant for moderate and severe severities only. The adjusted linear regression model identified that toothwear accounted for 0.02% of the variance in total OHIP-14 scores. Females, younger individuals and less deprived individuals showed a greater association between toothwear and OHRQoL. CONCLUSIONS: In this general population sample, there was a small significant association between toothwear and OHRQoL impacts. However, the association was only significant for more severe categories of toothwear.


Assuntos
Saúde Bucal , Qualidade de Vida , Adulto , Feminino , Humanos , Inquéritos e Questionários , Reino Unido
11.
JDR Clin Trans Res ; 4(3): 229-238, 2019 07.
Artigo em Inglês | MEDLINE | ID: mdl-30931715

RESUMO

INTRODUCTION: Evidence of the effectiveness of oral health promotion strategies among children from different socioeconomic backgrounds is necessary to support the implementation of public health interventions. OBJECTIVES: This study aimed to test the effectiveness of a school-based intervention to enhance the sense of coherence (SOC) and oral health-related quality of life (OHRQoL) of socially vulnerable Brazilian children. Furthermore, we explored the pathways by which the intervention may improve OHRQoL and SOC, assessing the direct and indirect pathways among demographic, clinical, socioeconomic, behavioral, and psychosocial variables. METHODS: In this cluster-randomized trial, 5 primary schools in Brazil were randomly allocated into intervention and control groups. The intervention comprised 7 sessions of SOC-based activities over 2 mo, which focused on making the school environment a place to develop children's SOC through involving teachers, school staff, and children. Trained teachers delivered the intervention. OHRQoL and SOC data were collected at baseline, 2 wk after the intervention, and at 3-mo follow-up. RESULTS: Information about oral clinical conditions, socioeconomic status, OHRQoL, and SOC was obtained from 356 children aged 8 to 14 y (165 in the intervention group and 191 in the control group). Children from the SOC-based intervention group reported fewer impacts of their oral health on their daily lives (Child Perceptions Questionnaire mean, 7.22) than those from the control group (9.14). The intervention group also reported greater improvement of SOC at 2 wk (SOC mean, 52.98) and 3 mo (52.75) than the control group (52.21 and 51.65, respectively). CONCLUSION: The intervention was effective in improving SOC and OHRQoL among socially vulnerable Brazilian children. Moreover, SOC was a relevant predictor for oral symptom and functional status in this population (Brazilian Clinical Trials Registry RBR-2N9NHJ). KNOWLEDGE TRANSFER STATEMENT: Clinicians and policy makers can use the results of this study to decide which approach to use when planning public health policy to improve the SOC and OHRQoL of socially vulnerable children. Our findings can assist policy makers in making more appropriate community health decisions in school environments that will improve community empowerment.


Assuntos
Promoção da Saúde , Saúde Bucal , Qualidade de Vida , Serviços de Saúde Escolar , Senso de Coerência , Adolescente , Brasil , Criança , Humanos , Instituições Acadêmicas
12.
Community Dent Health ; 36(1): 55-62, 2019 Feb 25.
Artigo em Inglês | MEDLINE | ID: mdl-30779497

RESUMO

Systems science methods offer an alternative way to approach problems within Dental Public Health by encouraging the consideration of the wider systems and structures in which oral health problems exist. Through such an approach, and consideration of interacting systems over multiple hierarchical levels, it may be possible to better understand the complexity associated with oral health related outcomes, and to improve theoretical understanding of these relationships. Simulation methods associated with systems science can also be used to help model and capture these real-world problems, and to help test the interactions associated with different elements of a system. The aim of this review is to summarise the concepts behind systems science approaches, and what they can offer the field of Dental Public Health. This will include an overview of the way systems science can approach problems associated with complexity, and the benefits these approaches can have. The main methods associated with the field will then be reviewed, along with examples of their application. This paper will then outline some of the main implications, both conceptual and methodological, that adopting systems science methods may have for Dental Public Health. Finally, the challenges associated with systems science will also be presented. It is hoped that this review will highlight the benefits of systems thinking, and how it can add to our conceptual knowledge of the contexts in which complex health problems are embedded.


Assuntos
Saúde Bucal , Saúde Pública , Humanos , Odontologia em Saúde Pública
13.
Community Dent Health ; 36(1): 3-4, 2019 Feb 25.
Artigo em Inglês | MEDLINE | ID: mdl-30807049

RESUMO

A Wicked Problem is a problem that is impossible or difficult to solve partly because of its multi-component nature and its interconnection with other problems (Rittel & Webber, 1973). There are many Wicked Problems in the field of population oral health; tooth decay being one. Tooth decay is a function of biology (destruction of our tooth enamel); a function of our physical environment (availability, advertising and accessibility of sugar sweetened foods and drinks, availability of dental services); a function of our social environment (norms of oral hygiene and sugar consumption vary by socio-economic strata, country, and cultures); a function of us as individuals (dietary habits, visiting the dentist, oral health beliefs, toothbrushing, use of fluoride, dental anxiety, income); and a function of politics (our city, region and national policies on oral health education, tax on sugar sweetened drinks, water fluoridation, dental payment systems).


Assuntos
Cárie Dentária , Saúde Bucal , Humanos , Escovação Dentária
14.
Community Dent Health ; 36(1): 17-21, 2019 Feb 25.
Artigo em Inglês | MEDLINE | ID: mdl-30667186

RESUMO

OBJECTIVES: Oral health related quality of life (OHRQoL) has been linked to malocclusion. We aimed (a) to investigate the association between malocclusion and OHRQoL among children, and (b) to examine whether this association varied by socioeconomic status. METHODS: Cross-sectional analysis of data for 4,217 children aged 12 & 15 years, who participated in the 2013 Children Dental Health Survey (CDHS); a nationally representative survey of children in England, Wales, and Northern Ireland. Malocclusion was determined using the modified Index of Orthodontic Treatment Need (IOTN). OHRQoL was measured using the Child Oral Impacts on Daily Performance (Child-OIDP). For socioeconomic status, we used the pupils' eligibility for free school meals (FSM) and Index of Multiple Deprivation (IMD). Adjusted marginal effects were estimated controlling for confounding variables. Separate analyses were carried out for the two age groups. RESULTS: Malocclusion was associated with 6% and 15% increases in the probability of reporting negative impact of OHRQoL for 12- and 15-year olds respectively, which was significant for 15-year olds (marginal effect=0.15, 95% CI=0.08-0.22). Malocclusion was associated with the prevalence of oral impacts for 12 year olds (marginal effect=0.1, 95% CI=0.02-0.17) and 15-year olds (marginal effect=0.2, 95% CI 95%=0.13-0.28) not eligible for FSM and for 15-year olds in the most (marginal effect=0.2, 95% CI=0.1-0.29) and least (marginal effect=0.26, 95% CI=0.13-0.4) deprived IMD quintiles. CONCLUSIONS: Malocclusion was associated with impacts on OHRQoL for 15-year olds. There was evidence of a relationship between SES, malocclusion and OHRQoL.


Assuntos
Má Oclusão , Saúde Bucal , Qualidade de Vida , Adolescente , Criança , Estudos Transversais , Inglaterra , Humanos , Irlanda do Norte , Fatores Socioeconômicos , Inquéritos e Questionários , País de Gales
15.
J Dent ; 81: 43-51, 2019 02.
Artigo em Inglês | MEDLINE | ID: mdl-30579857

RESUMO

OBJECTIVES: We aimed to understand why German dentists remain reluctant about selective carious tissue removal (SE), and to develop and test two interventions for changing dentists' behavior. METHODS: Ten one-to-one interviews with German dentists were conducted, and identified themes linked to the Behavioral Change Wheel to develop two interventions. The intervention "Guideline" summarized a scientific statement on SE, while the intervention "Tool" simulated dentists having a removal tool (self-limiting handpiece) allowing them to reliably perform SE. For testing these interventions, a postal behavioral-change simulation-experiment was performed on German dentists (n = 1226/intervention), delivered via sealed envelopes. Dentists were first, without knowledge of the intervention, asked to fill out a questionnaire, including a question on their simulated removal behavior in deep lesions in vital teeth, measured via the dentin hardness dentists would leave close to the pulp. After opening the sealed envelope and receiving the simulated intervention, dentists filled out a second identical questionnaire. RESULTS: Based on identified barriers (lack of guidelines, discrepancy between established and "new" knowledge, lack of routine) and facilitators (understanding the biological foundations for SE, knowing it was evidence-based, having reliable criteria for determining the endpoint of SE), the two interventions were developed. 504 dentists participated in the experiment (response rate:24.9%). For both interventions, the outcome behavior improved significantly after the intervention (p < 0.001), with 29.6% (guideline) and 17.9% (tool) changing their behavior towards SE, respectively. There were no significant differences in the outcome behavior between the two interventions (p = 0.933). CONCLUSION: Systematically developed behavior-change interventions may be efficacious to improve the uptake of SE. CLINICAL SIGNIFICANCE: Understanding the barriers and facilitators for applying SE facilitates the development of interventions which may be efficacious for changing carious tissue removal.


Assuntos
Cárie Dentária , Padrões de Prática Odontológica , Dente , Dentina , Odontólogos , Humanos , Pesquisa Qualitativa
16.
Biomaterials ; 178: 134-146, 2018 09.
Artigo em Inglês | MEDLINE | ID: mdl-29929183

RESUMO

Oral lichen planus (OLP) and recurrent aphthous stomatitis (RAS) are chronic inflammatory conditions often characterised by erosive and/or painful oral lesions that have a considerable impact on quality of life. Current treatment often necessitates the use of steroids in the form of mouthwashes, creams or ointments, but these are often ineffective due to inadequate drug contact times with the lesion. Here we evaluate the performance of novel mucoadhesive patches for targeted drug delivery. Electrospun polymeric mucoadhesive patches were produced and characterised for their physical properties and cytotoxicity before evaluation of residence time and acceptability in a human feasibility study. Clobetasol-17-propionate incorporated into the patches was released in a sustained manner in both tissue-engineered oral mucosa and ex vivo porcine mucosa. Clobetasol-17 propionate-loaded patches were further evaluated for residence time and drug release in an in vivo animal model and demonstrated prolonged adhesion and drug release at therapeutic-relevant doses and time points. These data show that electrospun patches are adherent to mucosal tissue without causing tissue damage, and can be successfully loaded with and release clinically active drugs. These patches hold great promise for the treatment of oral conditions such as OLP and RAS, and potentially many other oral lesions.


Assuntos
Adesivos/farmacologia , Clobetasol/farmacologia , Sistemas de Liberação de Medicamentos , Mucosa Bucal/efeitos dos fármacos , Muco/química , Animais , Morte Celular/efeitos dos fármacos , Humanos , Ratos , Suínos , Fatores de Tempo
17.
J Dent Res ; 97(10): 1129-1136, 2018 09.
Artigo em Inglês | MEDLINE | ID: mdl-29608864

RESUMO

Much research on children's oral health has focused on proximal determinants at the expense of distal (upstream) factors. Yet, such upstream factors-the so-called structural determinants of health-play a crucial role. Children's lives, and in turn their health, are shaped by politics, economic forces, and social and public policies. The aim of this study was to examine the relationship between children's clinical (number of decayed, missing, and filled teeth) and self-reported oral health (oral health-related quality of life) and 4 key structural determinants (governance, macroeconomic policy, public policy, and social policy) as outlined in the World Health Organization's Commission for Social Determinants of Health framework. Secondary data analyses were carried out using subnational epidemiological samples of 8- to 15-y-olds in 11 countries ( N = 6,648): Australia (372), New Zealand (three samples; 352, 202, 429), Brunei (423), Cambodia (423), Hong Kong (542), Malaysia (439), Thailand (261, 506), United Kingdom (88, 374), Germany (1498), Mexico (335), and Brazil (404). The results indicated that the type of political regime, amount of governance (e.g., rule of law, accountability), gross domestic product per capita, employment ratio, income inequality, type of welfare regime, human development index, government expenditure on health, and out-of-pocket (private) health expenditure by citizens were all associated with children's oral health. The structural determinants accounted for between 5% and 21% of the variance in children's oral health quality-of-life scores. These findings bring attention to the upstream or structural determinants as an understudied area but one that could reap huge rewards for public health dentistry research and the oral health inequalities policy agenda.


Assuntos
Saúde Bucal/estatística & dados numéricos , Adolescente , Criança , Estudos Transversais , Índice CPO , Atenção à Saúde/legislação & jurisprudência , Atenção à Saúde/organização & administração , Atenção à Saúde/estatística & dados numéricos , Feminino , Humanos , Masculino , Política Pública , Qualidade de Vida , Determinantes Sociais da Saúde/estatística & dados numéricos
18.
Implement Sci ; 13(1): 54, 2018 04 06.
Artigo em Inglês | MEDLINE | ID: mdl-29625615

RESUMO

BACKGROUND: This study aimed to identify barriers and enablers for dentists managing non-cavitated proximal caries lesions using non- or micro-invasive (NI/MI) approaches rather than invasive and restorative methods in New Zealand, Germany and the USA. METHODS: Semi-structured interviews were conducted, focusing on non-cavitated proximal caries lesions (radiographically confined to enamel or the outer dentine). Twelve dentists from New Zealand, 12 from Germany and 20 from the state of Michigan (USA) were interviewed. Convenience and snowball sampling were used for participant recruitment. A diverse sample of dentists was recruited. Interviews were conducted by telephone, using an interview schedule based on the Theoretical Domains Framework (TDF). RESULTS: The following barriers to managing lesions non- or micro-invasively were identified: patients' lacking adherence to oral hygiene instructions or high-caries risk, financial pressures and a lack of reimbursement for NI/MI, unsupportive colleagues and practice leaders, not undertaking professional development and basing treatment on what had been learned during training, and a sense of anticipated regret (anxiety about not restoring a proximal lesion in its early stages before it progressed). The following enablers were identified: the professional belief that remineralisation can occur in early non-cavitated proximal lesions and that these lesions can be arrested, the understanding that placing restorations weakens the tooth and inflicts a cycle of re-restoration, having up-to-date information and supportive colleagues and work environments, working as part of a team of competent and skilled dental practitioners who perform NI/MI (such as cleaning or scaling), having the necessary resources, undertaking ongoing professional development and continued education, maintaining membership of professional groups and a sense of professional and personal satisfaction from working in the patient's best interest. Financial aspects were more commonly mentioned by the German and American participants, while continuing education was more of a focus for the New Zealand participants. CONCLUSIONS: Decisions on managing non-cavitated proximal lesions were influenced by numerous factors, some of which could be targeted by interventions for implementing evidence-based management strategies in practice.


Assuntos
Tomada de Decisões , Cárie Dentária/terapia , Esmalte Dentário , Odontólogos/psicologia , Padrões de Prática Odontológica/estatística & dados numéricos , Cárie Dentária/classificação , Feminino , Humanos , Entrevistas como Assunto , Masculino , Pesquisa Qualitativa
19.
Health Qual Life Outcomes ; 15(1): 218, 2017 Nov 13.
Artigo em Inglês | MEDLINE | ID: mdl-29132377

RESUMO

BACKGROUND: This study aims to cross-culturally adapt the original English-language COHIP-SF 19 to Arabic culture and to test its psychometric properties in a community sample. METHODS: The Arabic COHIP-SF 19 was developed and its psychometric properties were examined in a population-based sample of 876 schoolchildren who were aged 12 years of age, in Benghazi, Libya. The Arabic COHIP-SF 19 was tested for its internal consistency, reproducibility, construct validity, factorial validity and floor as well as ceiling effects. A Mann-Whitney U test was used to compare the mean scores of COHIP-SF 19 by participants' caries status and self-reported oral health rating, satisfaction and treatment need. RESULTS: The Arabic COHIP-SF 19 was successfully and smoothly developed. It showed an acceptable level of equivalence to the original version. Overall, the internal consistency and reproducibility were acceptable to excellent, with a Cronbach's alpha of 0.84 and an intra-class correlation coefficient (ICC) of 0.76. All hypotheses predefined to test construct validity were confirmed. That is, children who had active dental caries, and who rated their oral health as poor, were not satisfied with their oral health or indicated the need of treatment had lower COHIP-SF 19 scores (P < 0.05). Floor or ceiling effects were not observed. The exploratory Factorial analysis suggested a 4-component solution and deletion of one item. CONCLUSION: The Arabic COHIP-SF 19 was successfully developed. The measure demonstrated satisfactory reliability and validity to estimate OHRQoL in a representative sample of 12-year-old schoolchildren.


Assuntos
Cárie Dentária/psicologia , Saúde Bucal , Qualidade de Vida , Autorrelato/normas , Criança , Feminino , Humanos , Líbia , Masculino , Satisfação do Paciente , Psicometria , Reprodutibilidade dos Testes , Estatísticas não Paramétricas , Traduções
20.
Aust Dent J ; 62(3): 355-362, 2017 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-28346696

RESUMO

BACKGROUND: This study aimed to adapt a measure of trust in physicians to trust in dentists and to assess the reliability and validity of the measure. METHODS: Questionnaire data were collected from a simple random sample of 596 Australian adults. The 11-item General Trust in Physicians Scale was modified to apply to dentists. RESULTS: The Dentist Trust Scale (DTS) had good internal consistency (α = 0.92) and exploratory factor analysis revealed a single-factor solution. Lower DTS scores were associated with less trust in the dentist last visited, having previously changed dentists due to unhappiness with the care received, currently having dental pain, usual visiting frequency, dental avoidance, and with past experiences of discomfort, gagging, fainting, embarrassment and personal problems with the dentist. CONCLUSIONS: The majority of people appear to exhibit trust in dentists. The DTS shows promising reliability and validity evidence.


Assuntos
Assistência Odontológica , Relações Dentista-Paciente , Odontólogos , Saúde Bucal , Confiança , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Austrália , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Opinião Pública , Inquéritos e Questionários , Adulto Jovem
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