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PLoS One ; 15(10): e0239210, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33017403

RESUMO

To evaluate the impact of Birdshot-Retinochoroidopathy (BSRC) and Serpiginous Choroiditis (SC) on depression, anxiety, and vision-related quality of life. 72 individuals (BSRC: n = 28, SC: n = 8; healthy control group (HC): n = 36) completed the Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder-7 (GAD-7), and the Visual Function Questionnaire (VFQ-25). Multivariate linear regression models were used to analyze different subscales of the PHQ-9, the GAD-7 and the VFQ-25. The results showed that the mean of PHQ-9 was significantly higher while the mean of the VFQ-25 and its´ subscales were consistently lower in the disease group compared to HC. The mean of GAD-7 was not significantly lower in the disease group compared to HC. Stratification for different disease severity stages and duration of disease did not reveal any differences in sum scores of PHQ-9, GAD-7, and VFQ-25, whereas there were significant differences in some subscales of the VFQ-25. We conclude that BSRC and SC patients show higher levels of depression and a reduced visual quality of life due to imminent loss of vision. Because depression and quality of life are adversely affected by lack of social contacts and functioning, psychological treatment should enable patients to maintain their independence and ability to social interaction. Psychosomatic care should be taken in account for the treatment of BSRC and SC.


Assuntos
Transtornos de Ansiedade/etiologia , Coriorretinopatia de Birdshot/patologia , Depressão/etiologia , Qualidade de Vida , Transtornos da Visão/psicologia , Síndrome dos Pontos Brancos/patologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Transtornos de Ansiedade/diagnóstico , Coriorretinopatia de Birdshot/complicações , Estudos de Casos e Controles , Estudos Transversais , Depressão/diagnóstico , Feminino , Humanos , Modelos Lineares , Masculino , Pessoa de Meia-Idade , Índice de Gravidade de Doença , Perfil de Impacto da Doença , Estatísticas não Paramétricas , Transtornos da Visão/etiologia , Acuidade Visual , Síndrome dos Pontos Brancos/complicações
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