[Infection and bacterial colonization of urogenital system in pregnancy, its effect on the clinical course of pregnancy, fetus and newborn]. / Infektsiia i bakterialnaia kolonizatsiia urogenitalii u beremennykh, vliianie na techenie beremennosti, plod i novorozhdennogo rebenka.

Colonization/infection of the genitals with Mycoplasma, group B Streptococci, and Chlamydia was studied in pregnant women. The course of gestation in women colonized with microorganisms was frequently aggravated by threatened spontaneous abortions, high incidence of hydramnion, late gestoses, pyelonephritis. For the newborns a reduced body mass and increased perinatal morbidity and mortality were characteristic. Transfer of microorganisms to the fetus and newborn was observed in 40-50% of cases and was not always associated with development of a disease. In cases of lethal outcomes of a neonatal disease pneumonia and placentitis were the constant morphological manifestations of the infection. In streptococcal and mycoplasmic infection the inflammation in the placenta was diffuse, involving the decium both in the placenta and in the extraplacental membranes.

[The optimization of the PCR for detecting cytomegalovirus in the urine of newborn infants]. / Optimizatsiia PTsR dlia obnaruzheniia tsitomegalovirusa v moche novorozhdennykh.

A quantitative comparison of 4-primer PCR-diagnosticum potentials for detection of cytomegalovirus DNA in urine specimens in different methods for DNA isolation was carried out. Comparatively simple DNA isolation procedures were considered for express diagnosis in clinical conditions. A scheme of successive use of diagnostic preparations was proposed.

[Mycoplasma infections of the human genital tract]. / Mikoplazmennye infektsii genital'nogo trakta cheloveka.

It has been shown that genital Mycoplasma may cause local and generalized diseases particular in parturients and premature neonates. For better laboratory diagnosis of Mycoplasma-induced infections, it is necessary to organize the production of culture media and diagnostic kits.