RESUMO
Article describes literature review of "atypical" osteomyelitis--osteonecrosis of facial bones among addicts to synthetic narcotics desomorphine and pervitin, different comorbidities, treatment strategy and prognosis were outlined
Assuntos
Transtornos Relacionados ao Uso de Anfetaminas/complicações , Osteonecrose da Arcada Osseodentária Associada a Difosfonatos/diagnóstico , Osteonecrose da Arcada Osseodentária Associada a Difosfonatos/terapia , Codeína/análogos & derivados , Usuários de Drogas , Metanfetamina/efeitos adversos , Dependência de Morfina/complicações , Osteonecrose da Arcada Osseodentária Associada a Difosfonatos/etiologia , Codeína/efeitos adversos , Ossos Faciais/efeitos dos fármacos , Ossos Faciais/patologia , Humanos , Osteomielite/induzido quimicamente , Osteomielite/diagnóstico , Osteomielite/terapiaAssuntos
Transtornos Relacionados ao Uso de Anfetaminas/patologia , Codeína/análogos & derivados , Ossos Faciais/patologia , Metanfetamina/toxicidade , Dependência de Morfina/patologia , Osteonecrose/patologia , Fósforo/toxicidade , Crânio/patologia , Transtornos Relacionados ao Uso de Anfetaminas/complicações , Codeína/toxicidade , Usuários de Drogas , Humanos , Dependência de Morfina/complicações , Osteonecrose/induzido quimicamente , Osteonecrose/cirurgiaRESUMO
Objective: To estimate the possibilities of using and systematizing computed tomographic findings in patients with toxic phosphorus necrosis of the jaw. Material and Methods: The investigation enrolled 87 patients diagnosed as having toxic phosphorus osteonecrosis. Radiation examination consisted of two stages: primary and repeated radiologic examinations in the postoperative period (final examination before hospital discharge). All the patients underwent skull X-ray and multislice computed tomography (MSCT). Results: Clinical and radiation examination revealed toxic phosphorus osteonecrosis of the maxilla and mandible in 29 (33%) cases. Osteonecrosis affected only the mandible in 40 (46%) cases and only the maxilla in 18 (21%) cases. In all the patients, computed tomography showed main trends in the X-ray semiotics of toxic phosphorus necrosis of the facial skeleton, such as periostitis; osteosclerosis; development a lesion having a "soap-bubble" appearance; nonspecific and inflammatory bone destruction. The bone, being destroyed, was replaced by pus; inflammatory granulations were absent; osteonecrosis occurred. These processes were characterized by the absence of an obvious demarcation zone along the edges of the process. Sequestration commonly occurred to form sinus tracts. The process involved the adjacent bones; there were reactive changes in the accessory sinuses. Conclusion: MSCT data are of highly informative value in evaluating the status of bone tissue and teeth and in detecting a concomitant abnormality in patients with osteonecrosis of the facial skeleton and may be used to plan surgical treatment for this category of patients.
Assuntos
Codeína/análogos & derivados , Mandíbula , Maxila , Tomografia Computadorizada Multidetectores/métodos , Osteonecrose/diagnóstico , Fósforo/toxicidade , Adulto , Analgésicos Opioides/química , Analgésicos Opioides/toxicidade , Codeína/química , Codeína/toxicidade , Feminino , Humanos , Drogas Ilícitas/química , Drogas Ilícitas/toxicidade , Masculino , Mandíbula/diagnóstico por imagem , Mandíbula/patologia , Maxila/diagnóstico por imagem , Maxila/patologia , Osteonecrose/induzido quimicamente , Osteonecrose/cirurgia , Cuidados Pré-Operatórios/métodos , Reprodutibilidade dos TestesRESUMO
The study included 15 patients with purulent inflammatory diseases of maxillofacial area and 25 patients with facial bone necrosis induced by synthetic drugs. Pro- and anti-inflammatory cytokines levels in saliva and wound fluid were analyzed in two groups. The results proved cytokines to play important role in jaw necrosis induced by drugs containing red phosphorus.
Assuntos
Citocinas/imunologia , Drogas Ilícitas/efeitos adversos , Doenças Maxilomandibulares/induzido quimicamente , Derivados da Morfina/efeitos adversos , Osteonecrose/induzido quimicamente , Adulto , Citocinas/análise , Feminino , Humanos , Interleucina-10/análise , Interleucina-10/imunologia , Doenças Maxilomandibulares/imunologia , Masculino , Pessoa de Meia-Idade , Derivados da Morfina/administração & dosagem , Osteonecrose/imunologia , Saliva/química , Saliva/imunologia , Fator de Crescimento Transformador beta/análise , Fator de Crescimento Transformador beta/imunologia , Fator de Necrose Tumoral alfa/análise , Fator de Necrose Tumoral alfa/imunologia , Adulto JovemRESUMO
The article describes clinical and radiological classification of osteonecrosis of the mandible in patients with drug dependence, surgical options presented on the basis of classification proposed. Clinical case of simultaneous application of individual plate of nikelid titanium in patient with osteonecrosis of the mandible is presented.
Assuntos
Placas Ósseas , Doenças Mandibulares/classificação , Doenças Mandibulares/cirurgia , Níquel , Osteonecrose/classificação , Osteonecrose/cirurgia , Transtornos Relacionados ao Uso de Substâncias/complicações , Titânio , Adulto , Humanos , Masculino , Doenças Mandibulares/complicações , Osteonecrose/complicações , Tomografia Computadorizada por Raios XRESUMO
OBJECTIVE: To elaborate a clinical and X-ray classification of osteonecrosis of the low jaw in people with desomorphine or pervitin addiction. MATERIAL AND METHODS: Ninety-two patients with drug addiction who had undergone orthopantomography, direct frontal X-ray of the skull, and multislice computed tomography, followed by multiplanar and three-dimensional imaging reconstruction were examined. One hundred thirty four X-ray films and 74 computed tomographic images were analyzed. RESULTS: The authors proposed a clinical and X-ray classification of osteonecrosis of the low jaw in people with desomorphine or pervitin addiction and elaborated recommendations for surgical interventions on the basis of the developed classification. CONCLUSION: The developed clinical and X-ray classification and recommendations for surgical interventions may be used to treat osteonecroses of various etiology.