Poly(methylmethacrylate-co-dimethyl acrylamide)-silver nanocomposite prevents biofilm formation in medical devices.

Aim: To investigate whether medical devices coated with a synthesized nanocomposite of poly(methylmethacrylate-co-dimethyl acrylamide) (PMMDMA) and silver nanoparticles (AgNPs) could improve their antibiofilm and antimicrobial activities. We also investigated the nanocomposite's safety. Materials & methods: The nanocomposite was synthesized and characterized using analytical techniques. Medical devices coated with the nanocomposite were evaluated for bacterial adhesion and hemolytic activity in vitro. Results: The nanocomposite formation was demonstrated with the incorporation of AgNPs into the polymer matrix. The nanocomposite proved to be nonhemolytic and significantly inhibited bacterial biofilm formation. Conclusion: The PMMDMA-AgNPs nanocomposite was more effective in preventing biofilm formation than PMMDMA alone and is a promising strategy for coating medical devices and reducing mortality due to hospital-acquired infections.

[Box: see text].

Healing and long-term prognosis of root-fractured permanent teeth: a retrospective longitudinal study.

AIM: The purpose of the present study was to evaluate permanent teeth with post-traumatic transversal root fractures, for their initial healing modality, the effect of candidate predictors and their long-term prognosis. METHODOLOGY: A retrospective longitudinal clinical study was conducted to evaluate records from patients bearing transversal root fractures in permanent teeth in order to radiographically assess short-term healing and non-healing events in the fracture line, their prognostic factors and their relationship with long term outcomes. The inter-fragmentary tissues were classified as healing: hard tissue (HT), connective tissue (CT) or connective tissue and bone (CT + B) and non-healing: interposition of granulation tissue (GT). A competing risk survival analysis was conducted to estimate the hazards of healing and non-healing events in the short-term and the effect of demographic, clinical, and treatment variables was assessed using the subdistribution regression model (Fine & Gray). RESULTS: Radiographic findings showed 61.4% of healing in the short-term being strongly influenced by the presence and type of concomitant injuries to the coronal fragment. Teeth with concomitant crown fractures (sHR 24.38, 95% CI [3.16-188.3], p = 0.0022), luxations with dislocations (sHR 10.58, 95% CI [1.37-81.9], p = 0.0240) and subluxations (HR 9.66, 95% CI [1.14-81.7], p = 0.0370) were more likely to present non-healing of root fractures in the short-term. The healing rate in the long-term was of 75.9%, most of them with interposition of bone and connective tissue. Kappa statistics demonstrated an overall agreement of 67.1% between short and long-term healing patterns, in special HT and CT + Bone modalities. CONCLUSION: Healing at the fracture site was the most frequent outcome, both in the short-term and in the long-term. Short-term healing modality was strongly influenced by the presence and type of concomitant injuries to the crown fragment, being the worst prognosis observed in root-fractured teeth with concomitant crown fractures, followed by concomitant luxations with dislocation. CLINICAL RELEVANCE: Post-traumatic transversal root fractures have a positive prognosis supporting therefore, a more conservative approach for these teeth before considering more radical treatments.

A retrospective cohort study of pulp prognosis in luxated permanent teeth: a competing risk analysis.

AIM: The present retrospective cohort study aimed to evaluate luxated permanent teeth for pulp prognosis and risk factors. METHODOLOGY: Case records and radiographs of 224 patients, involving 427 luxated permanent teeth, referred for treatment at the Dental Trauma Center-School of Dentistry, Universidade Federal de Minas Gerais, (DTC-SD-UFMG) from 2014 to 2022, were assessed for pulp prognosis classified as vitality, necrosis and pulp canal obliteration (PCO). A competing risk survival analysis estimated the hazards of the three outcomes, and the effect of demographic, clinical and treatment variables was tested using a cause specific Cox regression model. RESULTS: Pulp vitality was found in163 teeth (38.2%), pulp necrosis in 120 teeth (28.1%) and 55 teeth (12.9%) developed PCO. Pulp vitality decreased in the presence of concomitant crown fractures (HR 0.38 95% CI [0.2-0.8] p = 0.006). The risk of pulp necrosis (HR 0.62 95% CI [0.4-0.96] p = 0.03) was lower in cases with open apices but increased with concomitant crown fractures (HR 4.0 95% CI [2.6-6.1] p = 0.001) and intrusions (HR 2.3 95% CI [1.2-4.1] p = 0.007). Lateral or extrusive luxations (HR 3.0 95% CI [1.3-6.9] p = 0.001) and open apices (HR 2.4 95% CI [1.2-4.7] p = 0.01) showed higher rates of PCO. CONCLUSION: Type of luxation, the diameter of the apical foramen, and the presence of concomitant crown fractures were main determinants of pulp prognosis after luxation injuries in permanent teeth. CLINICAL RELEVANCE: Pulp prognosis after tooth luxation is dependent on the presence and direction of tooth displacement together with infection control. CLINICAL TRIAL REGISTRATION: Not applicable.

Prevalence of dental, oral, and maxillofacial traumatic injuries among domestic violence victims: A systematic review and meta-analysis.

BACKGROUND/AIMS: Domestic violence (DV) encompasses a series of abusive behaviors, perpetrated in a family environment, against individuals of all ages and genders. Injuries to the head, neck, and face are frequent findings among victims of abuse, negatively impacting their quality of life. Although oral and maxillofacial injuries (OMFI) and traumatic dental injuries (TDI) are commonly diagnosed among DV victims, their prevalence is still unknown. This systematic review was aimed to assess the prevalence of OMFI and TDI among victims of DV. METHODS: The protocol of the review was registered in PROSPERO (CRD42023424235). Literature searches were performed in eight electronic databases, up to August 7th, 2023. Observational studies published in the Latin-roman alphabet and reporting the prevalence of OMFI and/or TDI were included. The Joanna Briggs Institute's critical appraisal tool, checklist for prevalence studies, was used for quality assessment. Results were presented as qualitative and quantitative syntheses. RESULTS: Seventeen studies, totaling 12,375 victims of domestic violence, were included. Meta-analyses showed an overall prevalence of 29% (95% CI: 15%-48%, I2 = 99%) and 4% (95% CI: 1%-10%, I2 = 98%) for OMFI and TDI, respectively. Higher pooled prevalence for OMFI (41%, 95% CI: 13%-46%, I2 = 99%) was demonstrated in samples with only women. OMFI was less prevalent (20%) among DV victims under 18, while TDI was lower among adults (1%). Hospital samples presented higher pooled prevalence of OMFI (32%), and forensic data from fatal victims presented higher prevalence of TDI (8%). CONCLUSION: The overall prevalence of OMFI and TDI in DV victims was 29% and 4%, respectively. Women victims of DV presented higher rates of OFMI (41%) and TDI (6%).

Traumatismos dentários na rede social Instagram: um estudo exploratório / Dental trauma on Instagram: an exploratory study / Traumatismos dentoalveolares en Instagram: un estudio exploratorio

Estudo exploratório realizado entre 14/02/2021 e 06/03/2021, visando mapear e caracterizar os perfis sobre traumatismos dentários no Instagram, analisar as publicações quanto ao teor e à qualidade do conteúdo, como também examinar a interação e a prática comunicativa. Foram incluídos 25 perfis que apresentavam baixa audiência e pequena atividade, considerando-se o número de seguidores, a frequência de atualização e o número de publicações. Dezoito perfis eram brasileiros e estavam vinculados a projetos de extensão de Instituições de Ensino Superior (IES). Realizou-se a análise de 13 posts dos três perfis ativos, e verificou-se que eles estavam em conformidade com os protocolos da Associação Internacional de Traumatologia Dentária. As práticas comunicativas eram informacionais não se configurando como espaços de aprendizagem colaborativa. Redes sociais on-line constituem-se atualmente em estratégias importantes para a divulgação científica e a participação cidadã, mas os limites e os desafios do seu uso devem ser levados em conta no planejamento das ações de comunicação institucional em saúde pública

Exploratory study made from 14/02/2021 to 06/03/2021, aiming to map and characterize the profiles about dental trauma on Instagram, besides analyzing the posts according to its content and quality, interac-tions and communicative practice. Twenty-five profiles were included and presented low audience and low activity, considering the number of followers, updating frequency and number of posts. Eighteen of these profiles were Brazilian and had links with Universities Extension Projects. Thirteen posts were analyzed on the three active profiles, and it was verified that they were in conformity to the International Association of Dental Traumatology (IADT). The communicative practices were international, not being configured as collaborative learning spaces. Social media are important strategies to scientific communication and citizen participation, but limits and challenges of its use must be considered on the planning of institutional public health communication

Estudio exploratorio realizado entre el 14/02/2021 y el 06/03/2021, con el objetivo de mapear y caracteri-zar perfiles sobre trauma dental en Instagram, además de analizar publicaciones sobre contenido y calidad del contenido, interaciones y la práctica comunicativa. Se incluyeron 25 perfiles que tenían baja audiencia y poca actividad, considerando el número de seguidores, frecuencia de actualización y número de publica-ciones. Dieciocho perfiles eran brasileños y estaban vinculados a proyectos de extensión de Instituciones de Educación Superior. Se realizó un análisis de 13 publicaciones de los tres perfiles activos y se verificó que cumplían con los protocolos de la Asociación Internacional de Traumatología Dental. Las prácticas comunicativas fueron informacionales, no configuradas como espacios de aprendizaje colaborativo. Las redes sociales constituyen estrategias importantes para la divulgación científica y la participación ciuda-dana, pero los límites y desafíos de su uso deben ser tomados en cuenta a la hora de planificar acciones de comunicación institucional en salud pública

Prevalence of traumatic dental injuries in emergency dental services: A systematic review and meta-analysis.

OBJECTIVES: This study aimed to perform a systematic review and meta-analysis regarding the prevalence of traumatic dental injuries (TDI) in emergency dental services. METHODS: Seven electronic and two grey literature databases were searched, up to December 2021, for studies that reported the TDI prevalence among dental emergencies. The Joanna Briggs Institute critical appraisal checklist for prevalence studies, and The Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach were used to assess the risk of bias and quality of evidence respectively. The R software was used to perform a proportion meta-analysis on a random-effects model to estimate the pooled prevalence and respective 95% CI. RESULTS: From a total of 1476 studies identified after excluding duplicates, 38 met the inclusion criteria, and another five were identified through hand searching, summing 43 included observational studies with a total sample of 209099 individuals searching for emergency dental care. The overall pooled prevalence of TDI was 15.4% (95% CI: 11%-21%, I² = 100%). Paediatric dental emergency services and age group from 0 to 21 years presented the highest prevalence, 29% (95% CI: 22%-38%, I² = 99.5%) and 24% (95% CI: 15%-35%, I² = 98%) respectively. CONCLUSIONS: The overall pooled prevalence of TDI in emergency dental services was 15.4%, and 24% in the age group under 21 years. Considering the impact of prompt and correct emergency care in the long-term prognosis of TDI, such knowledge is relevant to organize emergency healthcare and support public policies in this area.

Perfil de usuários com necessidades de cuidados paliativos vinculados a uma Unidade Básica de Saúde no município de Porto Alegre/RS / User profiles with palliative care needs linked to a primary healthcare center in the city of Porto Alegre, RS

O fortalecimento em Cuidados Paliativos (CP) na Atenção Primária à Saúde (APS) aumenta a qualidade do atendimento no fim de vida e possibilita redução de complicações por longas internações. O objetivo deste trabalho foi analisar dados sobre a mortalidade ocorrida em portadores de doenças crônicas avançadas não transmissíveis vinculados à Unidade Básica de Saúde Vila Floresta do Grupo Hospitalar Conceição (USVF-GHC) e verificar quantos destes seriam elegíveis aos CP. Trata-se de uma pesquisa de caráter transversal, descritiva e de abordagem quantitativa e retrospectiva. Os dados são provenientes de registros eletrônicos em saúde, do relatório de monitoramento gerencial, dos prontuários na USVF-GHC e da vigilância epidemiológica de Porto Alegre. Utilizou-se a escala Palliative Care Screening Tool (PCST) para critério de elegibilidade à CP. De um total de 155 pessoas que faleceram e moravam no território de atuação da USVF-GHC no ano de 2019, 55,2%(n=86) eram do sexo feminino, 54,2%(n=84) eram idosos com mais de 80 anos, 23,9%(n=37) tinham o tempo entre diagnóstico e óbito com mais de 5 anos, em 69,7%(n=108) dos casos o local de falecimento foi o hospital, 66,5%(n=103) não tinham prontuário, para 34,8%(n=54) foram as neoplasias as principais causas de óbito e 42,6%(n=66) foram considerados elegíveis aos CP segundo a PCST. Conclui-se que o perfil de pessoas com diagnóstico há mais de cinco anos da doença que resultou no óbito poderia ser observado com maior atenção pelas equipes da APS no que diz respeito aos CP, aumentando as buscas ativas e estabelecendo comunicação efetiva com os hospitais na transferência de cuidados.

Strengthening in Palliative Care (PC) in Primary Healthcare (PHC) increases the quality of care at the end of life and reduces complications from long hospitalizations. The objective of this work was to analyze data on mortality that occurred in patients with advanced chronic non-communicable diseases associated with the Vila Floresta Primary Healthcare Center of the Conceição Hospital Group (VFPHC-CHG) and to verify how many of these would be eligible to PC. It is a transverse, descriptive and quantitative and retrospective approach research. Data come from electronic health records, management monitoring report, VFPHC-CHG medical records and Porto Alegre Epidemiological Surveillance. The Palliative Care Screening Tool (PCST) scale for PC eligibility criterion. Out of a total of 155 people who died and lived in the VFPHC-CHG covered territory in 2019, 55.2% (n = 86) were female, 54.2% (n = 84) were elderly and more 80 years old, 23.9% (n = 37) had died within five years after diagnosis, in 69.7% (n = 108) of cases the place of death was the hospital, 66.5% (n = 103) had no medical record, were neoplasms the main causes of death in 34.8%(n = 54), and 42.6% (n = 66) were considered eligible for PC according to PCST. It is concluded that the profile of people with diagnosis for over five years of the disease that resulted in death could be observed more carefully by PHC teams regarding PC, increasing the search for those who are eligible and establishing effective communication with hospitals in care transfer.

Increasing transplantability in Brazil: time to discuss Kidney Paired Donation / Doação renal pareada no Brasil: tempo para reflexão

Abstract Introduction: Kidney transplantation (KT) is the best treatment for chronic kidney disease. In Brazil, there are currently more than 26 thousand patients on the waitlist. Kidney Paired Donation (KPD) offers an incompatible donor-recipient pair the possibility to exchange with another pair in the same situation, it is a strategy to raise the number of KT. Discussion: KPD ceased being merely an idea over 20 years ago. It currently accounts for 16.2% of living donors KT (LDKT) in the USA and 8% in Europe. The results are similar to other LDKT. It is a promising alternative especially for highly sensitized recipients, who tend to accumulate on the waitlist. KPD is not limited to developed countries, as excellent results were already published in India in 2014. In Guatemala, the first LDKT through KPD was performed in 2011. However, the practice remains limited to isolated cases in Latin America. Conclusion: KPD programs with different dimensions, acceptance rules and allocation criteria are being developed and expanded worldwide to meet the demands of patients. The rise in transplantability brought about by KPD mostly meets the needs of highly sensitized patients. The Brazilian transplant program is mature enough to accept the challenge of starting its KPD program, intended primarily to benefit patients who have a low probability of receiving a transplant from a deceased donor.

Resumo Introdução: O transplante renal (TxR) é sabidamente o melhor tratamento para doença renal crônica. No Brasil, mais de 26 mil pacientes aguardam em lista atualmente. A doação renal pareada (DRP) oferece a um par de doador/receptor incompatível a possibilidade de trocar com outro par na mesma situação, representando uma estratégia para aumentar o número de TxR. Discussão: A DRP deixou de ser apenas uma ideia há mais de 20 anos. Atualmente é responsável por 16,2% dos TxR com doador vivo (TxRDV) nos EUA e 8% na Europa. Os resultados são semelhantes a outros TxRDV. Essa modalidade representa uma alternativa promissora, especialmente para os receptores hipersensibilizados que tendem a se acumular em lista de espera. A DRP não está limitada a países desenvolvidos. Em 2014, a Índia já publicava excelentes resultados. Na Guatemala, o primeiro TxRDV através de DRP aconteceu em 2011. Porém, a prática permanece limitada a casos isolados na América Latina. Conclusão: Programas de DRP com diferentes dimensões, regras para aceitação e critérios para alocação estão sendo desenvolvidos e expandidos mundialmente com o objetivo de atender às demandas dos pacientes. O aumento na capacidade de transplantar trazido pela DRP vem ao encontro especialmente das necessidades dos pacientes hipersensibilizados. O programa de TxR brasileiro tem maturidade para assumir o desafio de iniciar o programa de DRP, com o objetivo de beneficiar principalmente seus pacientes que estão em maior desvantagem por apresentarem baixas chances de transplante com doadores falecidos.

Rhinoviruses as critical agents in severe bronchiolitis in infants

Abstract Objectives: To detect RSV or other thirteen respiratory viruses as possible causer agent of bronchiolitis in infants. Method: This is an epidemiological analytical study, conducted using a nasopharyngeal aspirate of 173 hospitalized children younger than two years old with severe bronchiolitis in three hospitals in the Campinas Metropolitan Region (CMR) during 2013-14. The data was statically evaluated by Pearson's chi-squared test with statistical significance of 0.05 and 95% confidence level. Results: As expected, the most prevalent viruses detected were RSV A and B in 47% and 16% of the samples, respectively. However, almost a third of severe bronchiolitis cases there were no detection of RSV, and the viruses more commonly detected were rhinoviruses, which were identified in almost a quarter of all positive samples for at least a viral agent. Conclusions: Although nothing could be concluded from the disease severity and clinicalepidemiological data, the present study's results indicate that severe bronchiolitis is not always related to RSV infections in children younger than two years old, and the rhinoviruses were more prevalent in these cases. These findings reinforce the need to carry out a

Increasing transplantability in Brazil: time to discuss Kidney Paired Donation.

INTRODUCTION: Kidney transplantation (KT) is the best treatment for chronic kidney disease. In Brazil, there are currently more than 26 thousand patients on the waitlist. Kidney Paired Donation (KPD) offers an incompatible donor-recipient pair the possibility to exchange with another pair in the same situation, it is a strategy to raise the number of KT. DISCUSSION: KPD ceased being merely an idea over 20 years ago. It currently accounts for 16.2% of living donors KT (LDKT) in the USA and 8% in Europe. The results are similar to other LDKT. It is a promising alternative especially for highly sensitized recipients, who tend to accumulate on the waitlist. KPD is not limited to developed countries, as excellent results were already published in India in 2014. In Guatemala, the first LDKT through KPD was performed in 2011. However, the practice remains limited to isolated cases in Latin America. CONCLUSION: KPD programs with different dimensions, acceptance rules and allocation criteria are being developed and expanded worldwide to meet the demands of patients. The rise in transplantability brought about by KPD mostly meets the needs of highly sensitized patients. The Brazilian transplant program is mature enough to accept the challenge of starting its KPD program, intended primarily to benefit patients who have a low probability of receiving a transplant from a deceased donor.

Socio-environmental and parasitological aspects of waste pickers in Minas Gerais, Brazil

The increase in the generation of Solid Urban Waste causes social, environmental problems and damages to the population's health. Professionals who work in the collection of recyclable waste are exposed to risks of contamination either by toxic elements or pathogenic organisms. The objective of the work was to estimate the types and prevalence of intestinal parasites inwaste pickers. A field research was carried out from December 2017 to April 2018 with the voluntary participation of 26 waste pickers belonging to three associations in the municipality of Conselheiro Lafaiete, Minas Gerais, Brazil (CAAE: nº 79937817.7.0000.8122). In addition to the application a socio-environmental questionnaire, each volunteer provided a stool sample for laboratory testing the parasitological examination. Of the 26 survey participants, four (15.4%) had a positive result and were infected by the parasites Giardia lamblia, Entamoebacoliand Iodamoeba butschlii. Among the main factors that can contribute to the infection these waste pickersare the ingestion of untreated water for consumption in addition to reduced access to Personal Protective Equipment(PPE) during waste management. One way to control the presence of parasites would be through health and environmental education actions, periodic parasitological examinations and permanent use of PPE.

Rhinoviruses as critical agents in severe bronchiolitis in infants.

OBJECTIVES: To detect RSV or other thirteen respiratory viruses as possible causer agent of bronchiolitis in infants. METHOD: This is an epidemiological analytical study, conducted using a nasopharyngeal aspirate of 173 hospitalized children younger than two years old with severe bronchiolitis in three hospitals in the Campinas Metropolitan Region (CMR) during 2013-14. The data was statically evaluated by Pearson's chi-squared test with statistical significance of 0.05 and 95% confidence level. RESULTS: As expected, the most prevalent viruses detected were RSV A and B in 47% and 16% of the samples, respectively. However, almost a third of severe bronchiolitis cases there were no detection of RSV, and the viruses more commonly detected were rhinoviruses, which were identified in almost a quarter of all positive samples for at least a viral agent. CONCLUSIONS: Although nothing could be concluded from the disease severity and clinical-epidemiological data, the present study's results indicate that severe bronchiolitis is not always related to RSV infections in children younger than two years old, and the rhinoviruses were more prevalent in these cases. These findings reinforce the need to carry out a viral diagnosis in the hospital emergency would be very appropriate for all cases of respiratory infections in children, even for diseases in which the primary etiological agent seems to be well known.

Avaliação do conhecimento dos ortodontistas sobre movimentação ortodôntica em dentes traumatizados / Evaluation of orthodontists' knowledge concerning orthodontic movement in traumatized teeth

Resumo O presente estudo teve como objetivo avaliar o conhecimento dos ortodontistas inscritos na Associação Brasileira de Ortodontia e Ortopedia Facial ­ Seção Minas Gerais (ABOR/MG) sobre a movimentação ortodôntica de dentes traumatizados. A pesquisa foi realizada por meio de um questionário eletrônico desenvolvido na plataforma Google Forms® e enviado via e-mail. O questionário foi baseado no trabalho de Tondelli et al.1 (2010), composto por 21 questões objetivas, o qual foi dividido em 3 partes: a parte 1 abordou os dados demográficos dos participantes; a parte 2 coletou informações a respeito do conhecimento sobre traumatismo dentoalveolar e a parte 3 buscou avaliar o conhecimento dos profissionais em relação à movimentação ortodôntica de dentes traumatizados. A amostra consistiu de 93 (32%) de 289 ortodontistas registrados na ABOR/MG que responderam voluntariamente ao questionário, sendo 52,7% do sexo masculino e 47,3% do sexo feminino. Quanto à formação, a maioria (58,1%) apresentava o curso de Especialização concluído, 34,4% tinham concluído Mestrado ou Doutorado. A maior parte da amostra tinha mais de 10 anos de exercício da Ortodontia (50,5%). Do total, 53,8% afirmaram que praticam exclusivamente Ortodontia em seu consultório e 91,4% responderam que já atenderam pacientes com traumatismo dentário. No entanto, 21,5% afirmaram que apenas às vezes perguntam sobre história prévia de dentes traumatizados. O tipo de trauma com respostas mais assertivas foi avulsão (95,7%), enquanto subluxação, foi a que teve menos respostas adequadas (75,3%). A maioria dos ortodontistas possui um nível de conhecimento considerado satisfatório em relação às classificações de traumas dentários. Porém, a conduta em relação à movimentação ortodôntica destes dentes ainda é inadequada e uma maior capacitação desses profissionais torna-se necessária para levar ao correto tratamento e ao melhor prognóstico do paciente com traumatismo dentário (AU)

Abstract The aim of the present study was to evaluate the knowledge of orthodontists of the Brazilian Orthodontics and Facial Orthopedics Association ­ Minas Gerais section (ABOR/MG) in relation to orthodontic movement of traumatized teeth. The research was conducted with an electronic questionnaire answered through the Google Forms® platform and sent to the participants by e-mail. A number of 21 objective questions, based on Tondelli's et al.1 (2010) work, were divided into 3 parts: the profile data of the professionals composed part 1; part 2 collected information on the knowledge of dentoalveolar trauma; and part 3 evaluated the professional's knowledge in relation to the orthodontic movement of traumatized teeth. The sample of the study was a total of 289 orthodontists registered in the ABOR/MG association: 93 of these answered the questionnaire (32%), in which 51% were men and 49% were women. In terms of professional qualification and education, most participants (58,1%) had Specialization and 53,8% had more than 10 years of experience in the area of Orthodontics. In total, 53,8% declared having practiced exclusively Orthodontics in their clinics and 91,4% have already treated patients with dental trauma. However, 21,5% affirmed that only sometimes they ask the patients about the previous trauma history. The type of trauma with the most correct answers was avulsion (95,7%) and subluxation was the lesion with the lowest number of adequate response (75,3%). Most orthodontics has a level of knowledge in regard to dental trauma considered to be satisfactory. On the other hand, their conduct in orthodontic movement is inadequate and more capacitation and training of these professionals are necessary for the correct treatment and prognosis of the traumatized patient. (AU)

Acolhimento na Faculdade de Odontologia da UFMG: humanização no atendimento dos pacientes / Welcoming Services at the School of Dentistry of UFMG: humanizing care in patient access

A Política Nacional de Humanização (PNH) foi criada em 2003 pelo Ministério da Saúde, em meio ànecessidade de se ampliar o convencional modelo sanitário baseado no eixo doença-cura para um modelo que abordasse, de maneira coletiva, a família e a comunidade. A modificação das estratégias de atuação/atendimento e da gestãodo Sistema Único de Saúde (SUS)tornou-se, então, uma prioridade. O objetivo desse artigo foi relatar a implementação das práticas de acolhimento para os usuários que buscam atendimento clínico na Faculdade de Odontologia daUniversidade Federal de Minas Gerais(FAO-UFMG). A partir dacriação do projeto de extensão "Acolhimento e Orientação ao Usuárioda FAO-UFMG",em agosto de 2017, dados quantitativosrelacionados à queixa principal e encaminhamento dos pacientes foram coletadosdas fichas clínicas específicas do projeto.Da análise desses dados, foi possível perceber que os usuários passaram a ser atendidos de forma mais humanizada, acolhedora, respeitosa e com maior qualidade, tendo sua trajetória terapêutica mais bem delineada. As ações implementadastambém repercutirampositivamentena logística de funcionamento do setor responsável pela recepção dos pacientes, nocuidado prestado pelos profissionais envolvidos na atenção à saúdee no aprendizadodos alunos, contribuindo para a consolidação do projeto,pautado nos pilares da extensão (AU).

The National Humanization Policy was created in 2003 by the Ministry of Health. This policy emerged due to the need to expand the health model based on the disease-healing axisclassification, to a model that collectively addressed the family and the community, respecting the context in which they live and theirlife experiences.Consequently, this led tothe change inthe action/attendance strategies and the SUS management becominga priority. The aim of this article was to report the implementation of welcoming practices for users seeking clinical care at the Schoolof Dentistry of Federal University of Minas Gerais (FAO-UFMG). Based onthe creation of the extension project "Welcomingand User Guidance ofFAO-UFMG,"in August 2017, quantitative data related to the main complaint and referral of patients were collected from the specific clinicalfiles of the project. Analysis of these datamade itpossible to note that users beganto be cared for in a morehumanized, welcoming, and respectfulmanner, with higher quality, and improved delineation of their therapeutic trajectory. The actions implemented also had a positive impact on theoperationallogistics of the sector responsible for receiving patients, on the care provided by the professionals involved in health care and on student learning, thereby contributing to the consolidation of the project, based on the pillars of extension (AU).

Expression of matrix metalloproteinases 2 and 9 in replanted teeth with external root resorption: A cross-sectional study.

OBJECTIVE: To evaluate matrix metalloproteinase (MMP) expression in replanted permanent teeth with external root resorption (ERR). DESIGN: The present cross-sectional study included 42 patients with replanted permanent teeth, presenting with progressive forms of ERR, and referred for extraction according to the rehabilitation treatment plan or due to root fractures. The control group consisted of 12 healthy premolars, from 5 patients with good periodontal health and no radiographic evidence of root resorption, referred for extraction for orthodontic reasons. Root fragments were processed soon after extraction, and the supernatant was collected to measure matrix metalloproteinase 2/tissue inhibitor of metalloproteinase 2 (MMP-2/TIMP-2) and matrix metalloproteinase 9/tissue inhibitor of metalloproteinases 2 (MMP-9/TIMP-2) complexes through a double-ligand enzyme-linked immunosorbent assay (ELISA). RESULTS: Case groups with external inflammatory root resorption (EIRR) or external replacement root resorption (ERRR) showed significantly higher levels of MMP-2/TIMP-2 and MMP-9/TIMP-2 complexes than the control group. Additionally, comparisons between the case groups demonstrated that the MMP-2/TIMP-2 complex also had significantly higher levels in the ERRR group (p < 0.001). CONCLUSIONS: Our results suggest that MMP-2 and MMP-9 participate in the pathobiology of both types of ERR. In addition, the higher levels of MMP-2/TIMP-2 complex in the ERRR group support common modulation mechanisms with physiological bone turnover.

Exploring the causes of the high incidence of delayed graft function after kidney transplantation in Brazil: a multicenter study.

This retrospective multicenter (n = 18) cohort study evaluated the incidence, risk factors, and the impact of delayed graft function (DGF) on 1-year kidney transplant (KT) outcomes. Of 3992 deceased donor KT performed in 2014-2015, the incidence of DGF was 54%, ranging from 29.9% to 87.7% among centers. Risk factors (lower-bound-95%CI OR upper-bound-95%CI ) were male gender (1.066 1.2491.463 ), diabetic kidney disease (1.053 1.2961.595 ), time on dialysis (1.005 1.0071.009 ), retransplantation (1.035 1.3971.885 ), preformed anti-HLA antibodies (1.011 1.3831.892 ), HLA mismatches (1.006 1.0661.130 ), donor age (1.011 1.0171.023 ), donor final serum creatinine (sCr) (1.239 1.3171.399 ), cold ischemia time (CIT) (1.031 1.0431.056 ), machine perfusion (0.401 0.5420.733 ), and induction therapy with rabbit antithymocyte globulin (rATG) (0.658 0.8000.973 ). Duration of DGF > 4 days was associated with inferior renal function and DGF > 14 days with the higher incidences of acute rejection, graft loss, and death. In conclusion, the incidence and duration of DGF were high and associated with inferior graft outcomes. While late referral and poor donor maintenance account for the high overall incidence of DGF, variability in donor and recipient selection, organ preservation method, and type of induction agent may account for the wide variation observed among transplant centers.

Comparison between immediate and delayed post space preparations: a systematic review and meta-analysis.

OBJECTIVES: This systematic review and meta-analysis compared the effects of immediate and delayed post space preparation on apical sealing. MATERIALS AND METHOD: Two independent authors conducted a systematic search (PubMed/Medline, Cochrane Library, and other databases, until February 2020) and a risk of bias evaluation. Only in vitro studies that compared the effects of immediate and delayed post space preparations on apical filling and adhesion of the post were eligible. RESULT: Of the 742 articles retrieved, 32 were included. Most of the studies used single-rooted human teeth and rotary files for root canal preparation, a single-cone technique for the filling protocol, and rotary instruments for post space preparation. Various delayed preparation times were evaluated: 8-72 h, 5-30 days (mainly 7 days), and 4 months. In nine studies, the delayed groups showed more apical leakage, while four studies reported more leakage in the immediate groups; ten studies found no significant difference. One study found more bacterial penetration in the delayed group, whereas three studies showed no significant difference. One study reported more voids in the delayed group, while another found no such difference. Three studies showed better post-bond strength in the delayed group, one in the immediate group, whereas three found no significant difference in post-bond strength. Three studies employing varied sealers for root canal fillings were considered for meta-analysis. Two subgroup analyses were also performed (one concerning the use of resin-based sealers (AH Plus), another for zinc oxide-eugenol-based sealers). The results of the meta-analysis showed that a delayed post space preparation led to a significantly higher apical leakage than an immediate preparation (mean difference = 0.41 mm, confidence interval = 0.24-0.59, p < 0.001). CONCLUSION: Delayed post space preparation seems to negatively influence apical sealing; however, further studies are needed to determine the influence of the timing of post space preparation on the other parameters. CLINICAL RELEVANCE: Immediate post space preparation may be the safest clinical choice to prevent apical leakage.