RESUMO
BACKGROUND: COVID-19 has high mortality rate mainly stemming from acute respiratory distress leading to respiratory failure (ARF). Aim of the study was to evaluate the management of severe ARF due to COVID-19 pneumonia using noninvasive ventilatory support (NIVS), studying safety and effectiveness of NIVS. METHODS: This is a retrospective, multicenter study. Primary outcomes were NIVS failure with intubation rate and hospital mortality. Secondary outcomes were hospital stay and factors related to NIVS failure and mortality. These outcomes were compared with patients intubated and admitted to ICU. RESULTS: One hundred sixty-two patients were hospitalized because of severe respiratory failure (PaO
Assuntos
COVID-19/complicações , Ventilação não Invasiva , Insuficiência Respiratória/terapia , Doença Aguda , Fatores Etários , Idoso , Feminino , Frequência Cardíaca , Mortalidade Hospitalar , Humanos , Unidades de Terapia Intensiva/estatística & dados numéricos , Tempo de Internação , Masculino , Pessoa de Meia-Idade , Análise Multivariada , Ventilação não Invasiva/efeitos adversos , Ventilação não Invasiva/métodos , Ventilação não Invasiva/estatística & dados numéricos , Insuficiência Respiratória/mortalidade , Taxa Respiratória , Estudos Retrospectivos , SARS-CoV-2 , Falha de Tratamento , Resultado do Tratamento , Tratamento Farmacológico da COVID-19RESUMO
OBJECTIVE: Tactile spatial acuity is routinely tested in neurology to assess the state of the dorsal column system. In contrast, spatial acuity for pain is not assessed, having never been systematically characterized. More than a century after the initial description of tactile acuity across the body, we provide the first systematic whole-body mapping of spatial acuity for pain. METHODS: We evaluated the 2-point discrimination thresholds for both nociceptive-selective and tactile stimuli across several skin regions. Thresholds were estimated using pairs of simultaneous stimuli, and also using successive stimuli. RESULTS AND INTERPRETATION: These two approaches produced convergent results. The fingertip was the area of highest spatial acuity, for both pain and touch. On the glabrous skin of the hand, the gradient of spatial acuity for pain followed that observed for touch. On the hairy skin of the upper limb, spatial acuity for pain and touch followed opposite proximal-distal gradients, consistent with the known innervation density of this body territory. Finally, by testing spatial acuity for pain in a rare participant completely lacking Aß fibers, we demonstrate that spatial acuity for pain does not rely on a functioning system of tactile primary afferents. This study represents the first systematic characterization of spatial acuity for pain across multiple regions of the body surface.
Assuntos
Discriminação Psicológica , Dor/patologia , Dor/fisiopatologia , Limiar Sensorial/fisiologia , Percepção Espacial/fisiologia , Tato/fisiologia , Adulto , Feminino , Dedos/inervação , Testa/inervação , Humanos , Masculino , Estimulação Física , Pele/inervação , Adulto JovemRESUMO
En la Facultad de Ciencias Sociales, el 7 de septiembre del 2001, la revista Claves, la Unidad Académica de Salud Mental de la U.D.H. Fernández de la Facultad de Medicina, UBA, el Proyecto UBACyT: Exclusión Social y Nuevos Padecimientos del Instituto de Investigaciones Gino Germani, de la Facultad de Ciencias Sociales, y el Instituto Internacional de Psicología Social Analítica de Venecia, Italia, organizaron un Foro Participativo. Se incluyen las ponencias de cada uno de los integrantes a partir de la presentación de dos situaciones obstétricas; Cinthia y María. Fue Secretaria del Foro la Lic. Viviana García