[Effect of disulfide bonds on lysozyme dynamics]. / Vliianie disul'fidnykh sviazei na dinamiku lizotsima.

The effect of destruction of disulfide bonds on the dynamics of proteins was studied by an example of lysozyme by the methods of molecular dynamics. In lysozyme, in the absence of disulfide bonds, the characteristic times of motions of secondary structure devices increased 3-7 times, whereas the amplitudes of fluctuations of secondary structure devices practically did not vary. In the absence of S-S-bonds, the volume of the molecule decreased approximately by 2%, primarily due to a "cleft" between the major and the small domains of lysozyme. Thus, disulfide bonds not only "glue" the secondary structure devices of the protein but also play a role of "rods", maintaining a certain free volume of the molecule necessary for the realization of its functions.

[Molecular dynamics of bending fluctuations in the protein secondary structures]. / Molekuliarnaia dinamika izgibnykh fluktuatsii élementov vtorichnoi struktury belkov.

A comparative study of the dynamics of protein secondary structure elements by the example of alpha-helices of myoglobin, barnase, polylysine, and polyglycine and beta-layers of barnase and GFP was carried out by the methods of molecular dynamics. The effective Young's moduli of both free secondary structure elements and those built in the protein globule were determined. A heterogeneity of the elastic properties of the secondary structure elements was found. The melting of myoglobin alpha-helix in a virtual viscous medium was studied.

[Molecular dynamics of oligopeptides. 4. Dynamic characteristics of frequently and rarely occurring dipeptide fragments of proteins]. / Molekuliarnaia dinamika oligopeptidov. 4. Dinamicheskie osobennosti chasto i redko vstrechaiushchikhsia dipeptidnykh fragmentov belkov.

The existence of differences in the dynamic organization of frequently and the rarely occurring dipeptide fragments in globular and membrane proteins was shown. The dynamic isomorphism and the collective degrees of freedom in these fragments were analyzed. A topological classification of the maps of the levels of free energy for pairs of dihedral angles of the main chain and side residues was carried out.

[Statistical distribution of dipeptides in protein structures and dynamic characteristics of some protein fragments]. / Statisticheskie raspredeleniia dipeptidov v belkovykh strukturakh i dinamicheskie svoistva nekotorykh belkovykh fragmentov.

Statistical distributions of the occurrence of dipeptide fragments in proteins were studied. Various algorithms of ordering of files of frequency distribution were used. A correlation of occurrence of pairs of amino acid residues in various classes of proteins was established. The problem of the dynamic compatibility of amino acid residues in protein structures is discussed. The dynamic properties of frequently and seldom occurring dimers of amino acids are compared.

[A photometric method of analysis of cyanides]. / Fotometricheskii sposob opredeleniia tsianidov.

The contributors propose a selective photometric technique for detection of sodium and potassium cyanides in different washings, sewage, overalls extraction. The technique was based on the formation of a polymetyne dye, and barbituric acid and pyridine reactions. It proved efficient in detecting the cyanides within 0.01-0.054 mg/dm3, 1-100 mg/l, 0.08-1.24 mg/dm3 with deviations not exceeding 23%. Duration of the test was limited to 25-30 min.

[A method of cleaning overalls contaminated with sodium cyanide]. / Sposob obezvrezhivaniia spetsodezhdy pri zagriaznenii natriia tsianidom.

The contributors propose a new technique of cleaning overalls in galvanic shops from crystalline natrium cyanide (NC) and alkaline solutions. The technique includes washing in hot 0.05% syntamide-5 solution for 4-5 min., double rinsing and centrifuging. The remaining quantity of NC on washed overalls does not exceed 0.02 mg/m2 (evaluated in hydrocyanic acid). Subsequent contaminations of the overalls with NC do not entail the accumulation of NC residual content. The physical and chemical characteristics of this type of overall washing are more preferable as compared to those attained through soaking in ferric sulfate solution.

[Metal osteosynthesis in fresh closed fractures of the diaphyses of long tubular bones]. / Metallicheskii osteosyntez pri svezhikh zakrytykh perelomakh diafizov dlinnykh trubchatykh kostei.

Metallic osteosynthesis must be used for fractures of the diaphysis of long tubular bones on the basis of strict indications. Its high efficiency can be reached by creation of the ideal adaptation, good interfragmental contact and absolute fixity of the fragments. The compression osteosynthesis is thought to be a perspective method.