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Arkh Patol ; 84(5): 28-34, 2022.
Artigo em Russo | MEDLINE | ID: mdl-36178219

RESUMO

The article contains an overview of the new WHO classification of thoracic tumors (2021). As in the previous edition of 2015, considerable attention is paid to neoplasms of the lungs and pleura. The article presents current data on molecular genetic features and morphological manifestations of a number of new lung tumors, with a detailed histological and immunohistochemical data. Thoracis undifferentiated tumor with SMARCA4 deficiency and bronchiolar adenoma are described. Emphasis is placed on the algorithms of morphological diagnostics, including a complete description of the tumor and facilitating the study in the practice of a pathologist. The main morphological criteria of mesothelial tumors of the pleura are given; describes in detail the procedure for assessing the degree of malignancy of diffuse epithelioid pleural mesothelioma and non-mucinous lung adenocarcinomas.


Assuntos
Neoplasias Pulmonares , Mesotelioma , Neoplasias Pleurais , DNA Helicases , Diagnóstico Diferencial , Humanos , Pulmão/patologia , Neoplasias Pulmonares/classificação , Neoplasias Pulmonares/diagnóstico , Neoplasias Pulmonares/patologia , Mesotelioma/classificação , Mesotelioma/diagnóstico , Mesotelioma/patologia , Proteínas Nucleares , Pleura/patologia , Neoplasias Pleurais/classificação , Neoplasias Pleurais/diagnóstico , Neoplasias Pleurais/patologia , Fatores de Transcrição , Organização Mundial da Saúde
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