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1.
Gastroenterol Clin Biol ; 32(6-7): 601-5, 2008.
Artigo em Francês | MEDLINE | ID: mdl-18462899

RESUMO

Hereditary multiple exostoses is an autosomal dominant bone disorder characterized by multiple cartilaginous tumors growing outward from metaphyses of long bones. These tumors are usually located in long bones of the limbs. Exostosis also called osteochondroma can cause many complications, the most serious being malignant transformation as chondrosarcoma. We report a rare phenotype of this disease in a young male patient who presents digestive symptoms caused by a voluminous degenerated lumbar exostosis with anterior abdominal development.


Assuntos
Exostose Múltipla Hereditária/complicações , Obstrução Intestinal/etiologia , Adulto , Exostose Múltipla Hereditária/diagnóstico , Humanos , Obstrução Intestinal/diagnóstico , Masculino
3.
Rev Med Interne ; 27(3): 244-7, 2006 Mar.
Artigo em Francês | MEDLINE | ID: mdl-16406163

RESUMO

INTRODUCTION: Neoplasia and lymphoproliferative disorders are sometimes reported in patients with systemic lupus erythematosus (SLE). However, the pathophysiological link between lymphoma and SLE is still a matter of debate. We report a new case of Burkitt's lymphoma occurring in a patient treated with immunosuppressive drugs for SLE. CASE REPORT: A 38-year-old woman with SLE treated for 10 years with immunosuppressive drugs was admitted for the rapid onset of multiple neuritis with cranial nerves palsy, without extra-neurological involvement. The cerebrospinal fluid was normal. A bone marrow biopsy revealed Burkitt's lymphoma. CONCLUSION: This is the third case reported of Burkitt's lymphoma occurring in SLE. Here we discuss the data of the literature and the possible pathophysiological links between Burkitt's lymphoma and SLE.


Assuntos
Linfoma de Burkitt/etiologia , Imunossupressores/efeitos adversos , Lúpus Eritematoso Sistêmico/complicações , Lúpus Eritematoso Sistêmico/tratamento farmacológico , Adulto , Biópsia , Medula Óssea/patologia , Linfoma de Burkitt/induzido quimicamente , Linfoma de Burkitt/patologia , Ciclofosfamida/efeitos adversos , Ciclosporina/efeitos adversos , Evolução Fatal , Feminino , Humanos , Imunossupressores/uso terapêutico , Lúpus Eritematoso Sistêmico/patologia
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