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1.
Medicina (B Aires) ; 81(4): 496-507, 2021.
Artigo em Espanhol | MEDLINE | ID: mdl-34453791

RESUMO

Our objective was to assess levels of knowledge, attitudes, and practices against COVID-19. A total of 3774 persons were surveyed between September 18 and October 16, 2020. Eighty% resided in Buenos Aires City or Buenos Aires Province: 58% had completed tertiary education; 72% worked either independently or as employees in the public or the private sector; 51% used a prepaid health care plan, 34% were covered by a trade union-based health system, and near 10% used the public health services. According to the socio-demographic variables analyzed, the population studied was representative of the middle class. A total of 7% had been diagnosed with COVID-19. There was a high level of knowledge about the disease, judging by the high proportion of correct answers (80-90%). Regarding the measures taken by the government, the answers varied widely ("correct", "inadequate", "harmful", "unnecessary", etc.). The medical staff was the preferred source of information; 44% of respondents felt protected by their health system; 28% would only seek healthcare when feeling very sick. There was a high degree of compliance with most protection measures, except for attendance to social events in poorly ventilated spaces (50%). The results of these studies contribute to establishing communication strategies for the prevention and control of COVID-19 and thus deal more efficiently with eventual outbreaks of the disease.


Nuestro objetivo fue evidenciar el nivel de conocimientos, actitudes y prácticas frente al COVID-19. Fueron encuestados 3774 individuos mayores de 16 años entre el 18/09/20 y el 16/10/20. El 80% residía en la ciudad de Buenos Aires o la Provincia de Buenos Aires. El 58% había completado estudio terciario. El 72% tenía actividad laboral independiente o en relación de dependencia pública o privada. Utilizaban el sistema de salud prepago el 51%, obra social laboral el 34%, y sistema público de salud cerca del 10%. De acuerdo a las variables socio-demográficas analizadas, la mayoría de la población fue representativa de la clase media. Del total de encuestados, el 7% tuvo diagnóstico de COVID-19. Observamos un alto nivel de conocimiento de la enfermedad, con 80 a 90% de respuestas correctas. En relación a las medidas adoptadas por las autoridades, los juicios emitidos variaron entre "correctas", "insuficientes", "perjudiciales", "innecesarias", etc. El 44% se sentía protegido por el sistema de salud. En cuanto a los referentes válidos para transmitir información, la respuesta preponderante fue el personal médico. En cuanto al momento deconsultar por síntomas, un porcentaje importante (28%) lo haría en forma tardía. Observamos un alto grado de cumplimiento de las medidas de protección, a excepción del ítem "Asistencia a reuniones" (50%). Los resultados de estos estudios contribuyen a establecer estrategias comunicacionales para la prevención y el control de la enfermedad y de ese modo enfrentar de forma más eficiente eventuales rebrotes de la enfermedad.


Assuntos
COVID-19 , Argentina/epidemiologia , Estudos Transversais , Conhecimentos, Atitudes e Prática em Saúde , Humanos , SARS-CoV-2 , Inquéritos e Questionários
2.
Medicina (B.Aires) ; 81(4): 496-507, ago. 2021. graf
Artigo em Espanhol | LILACS | ID: biblio-1346501

RESUMO

Resumen Nuestro objetivo fue evidenciar el nivel de conocimientos, actitudes y prácticas frente al COVID-19. Fueron encuestados 3774 individuos mayores de 16 años entre el 18/09/20 y el 16/10/20. El 80% residía en la ciudad de Buenos Aires o la Provincia de Buenos Aires. El 58% había completado estudio terciario. El 72% tenía actividad laboral independiente o en relación de dependencia pública o privada. Utilizaban el sistema de salud prepago el 51%, obra social laboral el 34%, y sistema público de salud cerca del 10%. De acuerdo a las variables socio-demográficas analizadas, la mayoría de la población fue representativa de la clase media. Del total de encuestados, el 7% tuvo diagnóstico de COVID-19. Observamos un alto nivel de conocimiento de la enfermedad, con 80 a 90% de respuestas correctas. En relación a las medidas adoptadas por las autoridades, los juicios emitidos variaron entre "correctas", "insuficientes", "perjudiciales", "innecesarias", etc. El 44% se sentía protegido por el sistema de salud. En cuanto a los referentes válidos para transmitir información, la respuesta preponderante fue el personal médico. En cuanto al momento deconsultar por síntomas, un porcentaje impor tante (28%) lo haría en forma tardía. Observamos un alto grado de cumplimiento de las medidas de protección, a excepción del ítem "Asistencia a reuniones" (50%). Los resultados de estos estudios contribuyen a establecer estrategias comunicacionales para la prevención y el control de la enfermedad y de ese modo enfrentar de forma más eficiente eventuales rebrotes de la enfermedad.


Abstract Our objective was to assess levels of knowledge, attitudes, and practices against COVID-19. A total of 3774 persons were surveyed between September 18 and October 16, 2020. Eighty% resided in Buenos Aires City or Buenos Aires Province: 58% had completed tertiary education; 72% worked either independently or as employees in the public or the private sector; 51% used a prepaid health care plan, 34% were covered by a trade union-based health system, and near 10% used the public health services. According to the socio-demographic variables analyzed, the population studied was representative of the middle class. A total of 7% had been diag nosed with COVID-19. There was a high level of knowledge about the disease, judging by the high proportion of correct answers (80-90%). Regarding the measures taken by the government, the answers varied widely ("correct", "inadequate", "harmful", "unnecessary", etc.). The medical staff was the preferred source of information; 44% of respondents felt protected by their health system; 28% would only seek healthcare when feeling very sick. There was a high degree of compliance with most protection measures, except for attendance to social events in poorly ventilated spaces (50%). The results of these studies contribute to establishing communication strategies for the prevention and control of COVID-19 and thus deal more efficiently with eventual outbreaks of the disease.


Assuntos
COVID-19 , Argentina/epidemiologia , Conhecimentos, Atitudes e Prática em Saúde , Estudos Transversais , Inquéritos e Questionários , SARS-CoV-2
3.
J Hepatobiliary Pancreat Sci ; 28(5): 443-449, 2021 May.
Artigo em Inglês | MEDLINE | ID: mdl-33636035

RESUMO

BACKGROUND: The reflux of pancreatic enzymes into the bile duct and the gallbladder is an abnormal phenomenon that plays a role in lithogenesis and carcinogenesis. Because the pressure of the common bile duct depends on the pressures of the sphincter of Oddi, its dysfunction would be reflected in an increase in the pressure of the common bile duct in patients with cholelithiasis. The objective of this study was to measure the pressures of the common bile duct in patients with and without cholelithiasis and to relate them to the presence of pancreatobiliary reflux. METHODS: A prospective case-control study was designed. The study universe was constituted by all patients undergoing total gastrectomy for gastric cancer stages I and II over 30 months. The primary outcome measure was to establish differences between common bile duct pressures in patients with and without cholelithiasis. RESULTS: Common bile duct pressures in patients with gallstones showed a significant elevation (16.9 mmHg) compared to patients without gallstones (3.3 mm Hg) (p < 0.0001). These pressures correlated with the levels of amylase and lipase in gallbladder bile; higher levels were found in patients with gallstones compared to patients without gallstones (P < 0.0001). CONCLUSIONS: Common bile duct pressure in patients with cholelithiasis was significantly higher compared to patients without cholelithiasis leading to pancreatobiliary reflux.


Assuntos
Cálculos Biliares , Esfíncter da Ampola Hepatopancreática , Bile , Estudos de Casos e Controles , Ducto Colédoco , Humanos
6.
World J Emerg Surg ; 13: 6, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29416555

RESUMO

The Global Alliance for Infections in Surgery appreciates the great effort of the task force who derived and validated the Sepsis-3 definitions and considers the new definitions an important step forward in the evolution of our understanding of sepsis. Nevertheless, more than a year after their publication, we have a few concerns regarding the use of the Sepsis-3 definitions.


Assuntos
Confiabilidade dos Dados , Sepse/classificação , Índice de Gravidade de Doença , Pressão Arterial , Consenso , Escala de Coma de Glasgow , Humanos , Escores de Disfunção Orgânica , Sensibilidade e Especificidade , Sepse/mortalidade
7.
Medicina (B Aires) ; 77(6): 465-468, 2017.
Artigo em Espanhol | MEDLINE | ID: mdl-29223936

RESUMO

The association of the spread of community infections with poverty and overcrowding is well known. In our hospital, located in José C. Paz, we assist sporadic cases of post-cesarean infections caused by community acquired methicillin-resistant Staphylococcus aureus (CaMRSA). In a prospective study of families treated at our hospital, we investigated the relationship between a history of skin and soft tissue infections (SSTI) and extreme overcrowding defined as households with unsatisfied basic needs type 3 (NBI 3). A total of 264 households were included in the study; 109 (41.3%) had a history of SSTI and 59 (22.3%) were NBI 3. A total of 61.0% of the NBI 3 households and 35.6% of the non-NBI 3 households reported SSTI (p = 0.00047). Using Google Maps, we georeferenced households and identified them on a NBI map adapted from the 2010 demographic census. In neighborhoods with NBI > 9.7%, 51.2% of the households had a history of SSTI. When NBI was < 9.7%, the percentage fell to 31.1% (p = 0.0019). These results are suggestive of an association of SSTI acquired in the community with overcrowding and poverty. The presence of CaMRSA in community SSTIs should be suspected. Vancomycin or clindamycin prophylaxis could be considered when cesarean deliveries are performed in women from areas with high NBI or with a history of SSTI.


Assuntos
Aglomeração , Staphylococcus aureus Resistente à Meticilina/isolamento & purificação , Dermatopatias Bacterianas/epidemiologia , Infecções dos Tecidos Moles/epidemiologia , Infecções Estafilocócicas/epidemiologia , Argentina/epidemiologia , Cesárea/efeitos adversos , Infecções Comunitárias Adquiridas/epidemiologia , Infecções Comunitárias Adquiridas/microbiologia , Infecções Comunitárias Adquiridas/transmissão , Características da Família , Feminino , Humanos , Masculino , Pobreza , Gravidez , Estudos Prospectivos , Dermatopatias Bacterianas/transmissão , Infecções dos Tecidos Moles/microbiologia , Infecções dos Tecidos Moles/transmissão , Infecções Estafilocócicas/microbiologia , Infecções Estafilocócicas/transmissão
8.
Medicina (B.Aires) ; 77(6): 465-468, dic. 2017. map, tab
Artigo em Espanhol | LILACS | ID: biblio-894522

RESUMO

La asociación entre diseminación de infecciones comunitarias, pobreza y hacinamiento es bien conocida. En nuestro hospital observamos casos esporádicos de infecciones post-cesárea por cepas de Staphylococcus aureus meticilino resistente de origen comunitario (SAMRCo). En un estudio prospectivo de familias de José C. Paz atendidas en nuestro hospital, investigamos la relación entre antecedentes de infecciones de piel y partes blandas (IPPB) y hacinamiento extremo (hogares con necesidades básicas insatisfechas tipo 3, (NBI 3). Fueron incluidos 264 hogares; 109 (41.3%) tenían historia de IPPB y 59 (22.3%) eran NBI 3. El 61.0% de los hogares NBI 3 y el 35.6% de los hogares no NBI 3 refirieron IPPB (p = 0.00047). Georreferenciamos los domicilios con Google Maps y los ubicamos en un plano de José C. Paz NBI del censo nacional 2010. En barrios con un porcentaje de NBI > 9.7%, el 51.2% de los hogares tuvo antecedentes de IPPB. Cuando este porcentaje era ≤ 9.7% el porcentaje bajó al 31.1% (p = 0.0019). Estos resultados son sugestivos de diseminación comunitaria de estas infecciones asociada a hacinamiento y barrios pobres. Se debe considerar la presencia de SAMRCo en IPPB comunitarias. Por ello, en mujeres procedentes de zonas con alto porcentaje NBI o con antecedentes de IPPB se podría considerar la inclusión de la vancomicina o la clindamicina en la profilaxis de los partos por cesárea.


The association of the spread of community infections with poverty and overcrowding is well known. In our hospital, located in José C. Paz, we assist sporadic cases of post-cesarean infections caused by community acquired methicillin-resistant Staphylococcus aureus (CaMRSA). In a prospective study of families treated at our hospital, we investigated the relationship between a history of skin and soft tissue infections (SSTI) and extreme overcrowding defined as households with unsatisfied basic needs type 3 (NBI 3). A total of 264 households were included in the study; 109 (41.3%) had a history of SSTI and 59 (22.3%) were NBI 3. A total of 61.0% of the NBI 3 households and 35.6% of the non-NBI 3 households reported SSTI (p = 0.00047). Using Google Maps, we georeferenced households and identified them on a NBI map adapted from the 2010 demographic census. In neighborhoods with NBI > 9.7%, 51.2% of the households had a history of SSTI. When NBI was < 9.7%, the percentage fell to 31.1% (p = 0.0019). These results are suggestive of an association of SSTI acquired in the community with overcrowding and poverty. The presence of CaMRSA in community SSTIs should be suspected. Vancomycin or clindamycin prophylaxis could be considered when cesarean deliveries are performed in women from areas with high NBI or with a history of SSTI.


Assuntos
Humanos , Masculino , Feminino , Gravidez , Infecções Estafilocócicas/epidemiologia , Aglomeração , Dermatopatias Bacterianas/epidemiologia , Infecções dos Tecidos Moles/epidemiologia , Staphylococcus aureus Resistente à Meticilina/isolamento & purificação , Argentina/epidemiologia , Pobreza , Infecções Estafilocócicas/microbiologia , Infecções Estafilocócicas/transmissão , Cesárea/efeitos adversos , Características da Família , Estudos Prospectivos , Infecções Comunitárias Adquiridas/microbiologia , Infecções Comunitárias Adquiridas/transmissão , Infecções Comunitárias Adquiridas/epidemiologia
9.
World J Emerg Surg ; 12: 34, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28775763

RESUMO

BACKGROUND: Antimicrobial Stewardship Programs (ASPs) have been promoted to optimize antimicrobial usage and patient outcomes, and to reduce the emergence of antimicrobial-resistant organisms. However, the best strategies for an ASP are not definitively established and are likely to vary based on local culture, policy, and routine clinical practice, and probably limited resources in middle-income countries. The aim of this study is to evaluate structures and resources of antimicrobial stewardship teams (ASTs) in surgical departments from different regions of the world. METHODS: A cross-sectional web-based survey was conducted in 2016 on 173 physicians who participated in the AGORA (Antimicrobials: A Global Alliance for Optimizing their Rational Use in Intra-Abdominal Infections) project and on 658 international experts in the fields of ASPs, infection control, and infections in surgery. RESULTS: The response rate was 19.4%. One hundred fifty-six (98.7%) participants stated their hospital had a multidisciplinary AST. The median number of physicians working inside the team was five [interquartile range 4-6]. An infectious disease specialist, a microbiologist and an infection control specialist were, respectively, present in 80.1, 76.3, and 67.9% of the ASTs. A surgeon was a component in 59.0% of cases and was significantly more likely to be present in university hospitals (89.5%, p < 0.05) compared to community teaching (83.3%) and community hospitals (66.7%). Protocols for pre-operative prophylaxis and for antimicrobial treatment of surgical infections were respectively implemented in 96.2 and 82.3% of the hospitals. The majority of the surgical departments implemented both persuasive and restrictive interventions (72.8%). The most common types of interventions in surgical departments were dissemination of educational materials (62.5%), expert approval (61.0%), audit and feedback (55.1%), educational outreach (53.7%), and compulsory order forms (51.5%). CONCLUSION: The survey showed a heterogeneous organization of ASPs worldwide, demonstrating the necessity of a multidisciplinary and collaborative approach in the battle against antimicrobial resistance in surgical infections, and the importance of educational efforts towards this goal.


Assuntos
Anti-Infecciosos/uso terapêutico , Gestão de Antimicrobianos/métodos , Infecções Intra-Abdominais/tratamento farmacológico , Complicações Pós-Operatórias/tratamento farmacológico , Estudos Transversais , Saúde Global/tendências , Humanos , Inquéritos e Questionários
10.
World J Emerg Surg ; 12: 29, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28702076

RESUMO

Intra-abdominal infections (IAIs) are common surgical emergencies and have been reported as major contributors to non-trauma deaths in the emergency departments worldwide. The cornerstones of effective treatment of IAIs are early recognition, adequate source control, and appropriate antimicrobial therapy. Prompt resuscitation of patients with ongoing sepsis is of utmost important. In hospitals worldwide, non-acceptance of, or lack of access to, accessible evidence-based practices and guidelines result in overall poorer outcome of patients suffering IAIs. The aim of this paper is to promote global standards of care in IAIs and update the 2013 WSES guidelines for management of intra-abdominal infections.


Assuntos
Guias como Assunto , Infecções Intra-Abdominais/tratamento farmacológico , Infecções Intra-Abdominais/cirurgia , Sociedades Médicas/tendências , Traumatismos Abdominais/tratamento farmacológico , Traumatismos Abdominais/cirurgia , Antibacterianos/uso terapêutico , Gerenciamento Clínico , Humanos , Escores de Disfunção Orgânica , Peritonite/tratamento farmacológico , Sepse/tratamento farmacológico , Sepse/cirurgia , Sociedades Médicas/organização & administração , Cirurgiões/organização & administração , Cirurgiões/tendências
11.
World J Emerg Surg ; 11: 33, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-27429642

RESUMO

Intra-abdominal infections (IAI) are an important cause of morbidity and are frequently associated with poor prognosis, particularly in high-risk patients. The cornerstones in the management of complicated IAIs are timely effective source control with appropriate antimicrobial therapy. Empiric antimicrobial therapy is important in the management of intra-abdominal infections and must be broad enough to cover all likely organisms because inappropriate initial antimicrobial therapy is associated with poor patient outcomes and the development of bacterial resistance. The overuse of antimicrobials is widely accepted as a major driver of some emerging infections (such as C. difficile), the selection of resistant pathogens in individual patients, and for the continued development of antimicrobial resistance globally. The growing emergence of multi-drug resistant organisms and the limited development of new agents available to counteract them have caused an impending crisis with alarming implications, especially with regards to Gram-negative bacteria. An international task force from 79 different countries has joined this project by sharing a document on the rational use of antimicrobials for patients with IAIs. The project has been termed AGORA (Antimicrobials: A Global Alliance for Optimizing their Rational Use in Intra-Abdominal Infections). The authors hope that AGORA, involving many of the world's leading experts, can actively raise awareness in health workers and can improve prescribing behavior in treating IAIs.


Assuntos
Anti-Infecciosos/farmacologia , Cooperação Internacional , Infecções Intra-Abdominais , Resistência Microbiana a Medicamentos , Humanos , Infecções Intra-Abdominais/diagnóstico , Infecções Intra-Abdominais/tratamento farmacológico , Infecções Intra-Abdominais/microbiologia , Testes de Sensibilidade Microbiana , Prognóstico
12.
World J Emerg Surg ; 10: 61, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-26677396

RESUMO

BACKGROUND: To validate a new practical Sepsis Severity Score for patients with complicated intra-abdominal infections (cIAIs) including the clinical conditions at the admission (severe sepsis/septic shock), the origin of the cIAIs, the delay in source control, the setting of acquisition and any risk factors such as age and immunosuppression. METHODS: The WISS study (WSES cIAIs Score Study) is a multicenter observational study underwent in 132 medical institutions worldwide during a four-month study period (October 2014-February 2015). Four thousand five hundred thirty-three patients with a mean age of 51.2 years (range 18-99) were enrolled in the WISS study. RESULTS: Univariate analysis has shown that all factors that were previously included in the WSES Sepsis Severity Score were highly statistically significant between those who died and those who survived (p < 0.0001). The multivariate logistic regression model was highly significant (p < 0.0001, R2 = 0.54) and showed that all these factors were independent in predicting mortality of sepsis. Receiver Operator Curve has shown that the WSES Severity Sepsis Score had an excellent prediction for mortality. A score above 5.5 was the best predictor of mortality having a sensitivity of 89.2 %, a specificity of 83.5 % and a positive likelihood ratio of 5.4. CONCLUSIONS: WSES Sepsis Severity Score for patients with complicated Intra-abdominal infections can be used on global level. It has shown high sensitivity, specificity, and likelihood ratio that may help us in making clinical decisions.

13.
J Gastrointest Cancer ; 46(4): 333-42, 2015 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-26490964

RESUMO

INTRODUCTION: Solitary fibrous tumors of the liver (SFTL) are uncommon tumors; to the present day, less than 50 cases has been reported in the English scientific literature, most of which behaved as benign tumors. The present article reports a new case of SFTL and has the main purpose of updating the current knowledge of SFTL because due to its rarity, its clinical presentation, study, treatment, and prognosis are not well known. The clinical presentation, radiologic study, surgical treatment, immunohistochemical study, and prognosis are updated and comprehensively discussed. METHODS: Using the common search engines, a search of the English literature was conducted for "Solitary Fibrous Tumor of The Liver," and the relevant articles were retrieved, reviewed, and analyzed. RESULTS: All published articles reported anecdotal SFTLs, or SFTLs were included in large series analyzing solitary fibrous tumors on different sites. CONCLUSION: The SFTL is an uncommon neoplasm. The clinical presentation is habitually indolent and its behavior is uncertain. In some cases, the SFTL acts as an aggressive sarcoma with poor prognosis. Currently, only surgery offers a therapeutic opportunity for these patients. Due to the lack of current knowledge of long-term behavior of supposedly benign SFTLs and to the lack of specific therapies, methodical long-term follow-up is essential to ensure the survival of patients treated for SFTL.


Assuntos
Neoplasias Hepáticas/diagnóstico , Tumores Fibrosos Solitários/diagnóstico , Humanos , Neoplasias Hepáticas/cirurgia , Masculino , Pessoa de Meia-Idade , Prognóstico , Tumores Fibrosos Solitários/cirurgia , Tomografia Computadorizada por Raios X
14.
Rev. colomb. cir ; 30(3): 230-239, jul.-set. 2015. ilus, tab
Artigo em Espanhol | LILACS, COLNAL | ID: lil-765590

RESUMO

El tumor fibroso solitario del hígado es infrecuente. Hasta la fecha, se han reportado menos de 50 casos en la literatura científica inglesa, la mayoría de los cuales se comportaron como tumores benignos. El objetivo del presente artículo es actualizar el conocimiento sobre este tumor porque, debido a su rareza, la presentación clínica, el estudio, el tratamiento y el pronóstico no son bien conocidos. Habitualmente, no produce sintomatología o es inespecífica y su comportamiento a largo plazo es incierto; no obstante, en algunos casos, se comporta agresivamente como un sarcoma de mal pronóstico. Actualmente, solo el tratamiento quirúrgico puede ofrecer una oportunidad terapéutica para estos pacientes. Debido a la falta de conocimiento sobre el comportamiento a largo plazo de estos tumores supuestamente benignos y a la falta de tratamiento médico específico, se sugiere el seguimiento metódico a largo plazo para garantizar la supervivencia de los pacientes operados por un tumor fibroso solitario del hígado.


Solitary fibrous tumors of the liver (SFTL) are uncommon tumors. To the present day less than 50 cases has been reported in the scientific English literature, most of which behaved as benign tumors. The present article has the main purpose of updating knowledge on SFTL because, due to its rarity, its clinical presentation, study, treatment and prognosis, are not well known. The clinical presentation, radiologic study, surgical treatment, immunohistochemical study and prognosis are updated and comprehensively discussed. The SFTL is an uncommon neoplasm. The clinical presentation is habitually indolent and its behavior is uncertain. In some cases, the SFTL acts as an aggressive sarcoma with poor prognosis. Currently, only surgery offers a therapeutic opportunity for these patients. Due to the lack of current knowledge on the long-term behavior of supposedly benign SFTLs and to the lack of specific therapies, methodical long-term follow-up is essential to ensure the survival of patients treated for SFTL.


Assuntos
Humanos , Fígado , Hemangiopericitoma , Hepatectomia , Neoplasias Hepáticas , Células-Tronco Mesenquimais , Tumor Fibroso Solitário Pleural
15.
World J Emerg Surg ; 10: 35, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-26269709

RESUMO

The open abdomen (OA) procedure is a significant surgical advance, as part of damage control techniques in severe abdominal trauma. Its application can be adapted to the advantage of patients with severe abdominal sepsis, however its precise role in these patients is still not clear. In severe abdominal sepsis the OA may allow early identification and draining of any residual infection, control any persistent source of infection, and remove more effectively infected or cytokine-loaded peritoneal fluid, preventing abdominal compartment syndrome and deferring definitive intervention and anastomosis until the patient is appropriately resuscitated and hemodynamically stable and thus better able to heal. However, the OA may require multiple returns to the operating room and may be associated with significant complications, including enteroatmospheric fistulas, loss of abdominal wall domain and large hernias. Surgeons should be aware of the pathophysiology of severe intra-abdominal sepsis and always keep in mind the option of using open abdomen to be able to use it in the right patient at the right time.

16.
Indian J Surg ; 77(Suppl 3): 1050-6, 2015 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-27011509

RESUMO

The systemic inflammatory response has been described in patients with appendicitis. However, its progression from onset of symptoms to diagnosis has not been characterized. The specific purpose of this study was to describe and characterize the systemic inflammatory response to appendicitis. A descriptive cross-sectional study was conducted. One hundred eighty-three patients were studied, divided into four groups from onset of symptoms to diagnosis. The primary outcome measure was to determine the systemic inflammatory response to appendicitis according to the established groups of time intervals. The secondary outcome measure was the analysis of C-reactive protein for the same purpose. The variables of the systemic inflammatory response, according to diagnostic intervals, showed non-significant differences in white blood cell count. The temperature rose constantly after 48 h, reaching its peak after 72 h (p = 0.001), and the respiratory rate rose after 73 h (p < 0.0001). After 73 h, most patients had three or four systemic inflammatory response criteria (p < 0.0001). C-reactive protein levels rose progressively, showing higher levels after 48 h (p = 0.005). The inflammatory response to appendicitis is progressive, being more marked along the timeline from onset of symptoms to diagnosis.

17.
Rev. colomb. cir ; 28(1): 54-63, ene.-mar. 2013. ilus, tab
Artigo em Espanhol | LILACS | ID: lil-675259

RESUMO

La hernia diafragmática complicada de presentación tardía constituye una urgencia quirúrgica debido a la isquemia y eventual necrosis y gangrena de los órganos herniados. Los órganos o estructuras que se encuentran con mayor riesgo de sufrir complicaciones por la hernia son el colon, el estómago, el bazo, el epiplón mayor y los intestinos. La necrosis y gangrena del estómago se deben a su estrangulamiento dentro de la hernia, lo que constituye una complicación grave y potencialmente mortal. El presente artículo resume brevemente la literatura científica relevante sobre el diagnóstico clínico y radiológico, y el tratamiento de la necrosis gástrica como complicación de la hernia diafragmática de presentación tardía.


Complicated diaphragmatic hernia with delayed presentation constitutes a surgical emergency due to ischemia and eventual necrosis and gangrene of the herniated organs. The organs or structures at greater risk of complications are colon, stomach, spleen, greater omentum, and small bowel. Gastric necrosis and gangrene are secondary to the twisting and strangulation of the stomach inside the hernia sac, constituting a severe and potentially lethal complication. This article reviews and briefly resumes the current relevant literature on the clinical and radiological diagnosis and the treatment of gastric necrosis as complication of diaphragmatic hernia with delayed presentation.


Assuntos
Hérnia Diafragmática , Estômago , Gastrectomia , Hérnia Diafragmática Traumática
18.
Indian J Surg ; 75(Suppl 1): 227-9, 2013 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-24426573

RESUMO

Multiple primary gastrointestinal stromal tumors (GIST) are an infrequent finding. Benign and malignant tumors could coexist in the same patient. We discuss one case of a benign jejunal GIST and a malignant ileal GIST coexisting in the same patient and present their radiological characteristics.

19.
World J Gastroenterol ; 18(34): 4639-50, 2012 Sep 14.
Artigo em Inglês | MEDLINE | ID: mdl-23002333

RESUMO

Chronic complications of symptomatic gallstone disease, such as Mirizzi syndrome, are rare in Western developed countries with an incidence of less than 1% a year. The importance and implications of this condition are related to their associated and potentially serious surgical complications such as bile duct injury, and to its modern management when encountered during laparoscopic cholecystectomy. The pathophysiological process leading to the subtypes of Mirizzi syndrome has been explained by means of a pressure ulcer caused by an impacted gallstone at the gallbladder infundibulum, leading to an inflammatory response causing first external obstruction of the bile duct, and eventually eroding into the bile duct and evolving to a cholecystocholedochal or cholecystohepatic fistula. This article reviews the life of Pablo Luis Mirizzi, describes the earlier and later descriptions of Mirizzi syndrome, discusses the pathophysiological process leading to the development of these uncommon fistulas, reviews the current diagnostic modalities and surgical approaches and finally proposes a simplified classification for Mirizzi syndrome intended to standardize the reports on this condition and to eventually develop a consensual surgical approach to this unexpected and seriously dangerous condition.


Assuntos
Síndrome de Mirizzi , História do Século XIX , História do Século XX , Humanos , Síndrome de Mirizzi/classificação , Síndrome de Mirizzi/diagnóstico , Síndrome de Mirizzi/história , Síndrome de Mirizzi/terapia
20.
Rev. colomb. cir ; 27(2): 129-138, abr. 2012. ilus, tab
Artigo em Espanhol | LILACS | ID: lil-650050

RESUMO

Introducción. La infrecuente situación clínica que constituye la gran masa inflamatoria encontrada durante una apendicectomía que llevó a una hemicolectomía y los hallazgos patológicos que causaron el proceso inflamatorio, son las razones que motivaron la revisión de los casos presentados durante los últimos 10 años en nuestra institución, con el objetivo de establecer sus características y la conducta apropiada. Pacientes y método. Se llevó a cabo un estudio retrospectivo y descriptivo de casos consecutivos. Se revisaron las historias clínicas de los pacientes adultos operados con diagnóstico de apendicitis entre 1999 y 2008. Durante este periodo, 2.175 pacientes fueron operados a través de una incisión de McBurney. En 39 casos (1,7 %) fue necesaria la hemicolectomía derecha. Resultados. En todos los casos se practicó anastomosis primaria íleo-colon. Se presentaron complicaciones en 69 % de los casos, con una mortalidad de 5 %. Según el estudio histopatológico, la condición más frecuente que causó la masa inflamatoria fue la apendicitis asociada a hiperplasia linfática focal (25 pacientes, 54 %, p<0,0001). Otras condiciones patológicas fueron: diverticulitis del colon derecho, diverticulitis cecal, necrosis de pared del colon y otros tumores del colon y del apéndice. Conclusiones. Los resultados de esta serie confirman que la hemicolectomía derecha en pacientes inicialmente programados para apendicectomía, es una situación inusual. Cuando ocurre, se debe a la presencia de una condición patológica compleja e inesperada. La hemicolectomía derecha con anastomosis primaria tiene una elevada morbilidad y mortalidad; sin embargo, ante los hallazgos y la duda diagnóstica, constituye una opción apropiada.


Introduction: The uncommon clinical condition resulting from a large inflammatory mass encountered at appendectomy that lead to a major colonic resection and the pathology findings motivated this review covering all cases operated on over the past 10 years at our institution, aiming to define the characteristics and adequate approach. Patients and methods: The present study is a retrospective descriptive review of consecutive cases. All clinical records of adult patients operated on for suspected acute appendicitis between 1999 and 2008 were reviewed. During this period 2,175 patients were approached through a McBurney incision. Of them, 39 patients (1.7%) required a right hemicolectomy and were the subject of this analysis. Results: A right hemicolectomy with primary anastomosis was performed in all cases. Complications developed in 69% cases, with 5% mortality. According to the histologic report, the most frequent condition causing the inflammatory mass was acute appendicitis with focal lymphatic hyperplasia (25 patients, 54%, p<0.0001). Other pathological conditions were: right colonic diverticulitis, cecal diverticulitis, colonic wall necrosis, and appendicular or colonic tumors. Conclusions: The results of this series confirm that a right colectomy in patients initially submitted to appendectomy is an unusual clinical scenario. When this occurs, it is due to serious and unexpected pathological conditions. Right colectomy with primary anastomosis has a high morbidity and mortality rates; however, when facing the findings and diagnostic concerns constitutes the appropriate choice.


Assuntos
Colectomia , Apendicectomia , Neoplasias do Apêndice , Neoplasias do Colo
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