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Georgian Med News ; (266): 80-85, 2017 May.
Artigo em Russo | MEDLINE | ID: mdl-28628020

RESUMO

According to the results, investigated methanolic extracts of endemic plant from Adjarian floristic region of Georgia do not have specific cytotoxicity against the cell lines of breast adenocarcinoma MCF-7 human, which is typical, e.g., for plant pigment curcumin. At the same time, the high specific cytotoxicity of 2 and 3 fractions towards keratinocytes gives reason for considering endemic plant extracts, of Adjarian floristic region of Georgia, as a potential pharmacological means for topical treatment of pathologies caused by increased proliferation of keratinocytes, such as psoriasis.


Assuntos
Citotoxinas/farmacologia , Erysimum/química , Extratos Vegetais/farmacologia , Antineoplásicos Fitogênicos/farmacologia , Linhagem Celular , República da Geórgia , Humanos , Queratinócitos/citologia , Queratinócitos/efeitos dos fármacos , Células MCF-7 , Metanol , Solventes
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