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1.
Clin Ter ; 150(4): 307-10, 1999.
Artigo em Italiano | MEDLINE | ID: mdl-10605170

RESUMO

Primary non-Hodgkin's lymphomas (NHL) of the breast represent less than 3% of extranodal NHL; in comparison to extranodal NHL at other sites, they are characterized by rapid progression and worse prognosis. We report a case of primary NHL of the breast treated, after surgery, with a sequential combination of chemotherapy and radiotherapy. Literature data suggest that the most important factors in therapeutic decisions making are the initial stage of the disease and the histological subtype.


Assuntos
Neoplasias da Mama/cirurgia , Linfoma não Hodgkin/cirurgia , Adulto , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Neoplasias da Mama/tratamento farmacológico , Neoplasias da Mama/patologia , Neoplasias da Mama/radioterapia , Terapia Combinada , Feminino , Humanos , Linfoma não Hodgkin/tratamento farmacológico , Linfoma não Hodgkin/patologia , Linfoma não Hodgkin/radioterapia , Prognóstico
2.
Clin Ter ; 150(2): 153-7, 1999.
Artigo em Italiano | MEDLINE | ID: mdl-10396865

RESUMO

We report a case of primary squamous cell carcinoma of the breast in a 58 years old woman. The diagnosis of this rare tumor is possible after excluding a skin primary lesion or an epidermoid cancer of a distant site. In reviewing the reported cases we didn't find any significant prognostic difference between this form and the breast adenocarcinoma with squamous metaplasia.


Assuntos
Neoplasias da Mama/diagnóstico por imagem , Carcinoma de Células Escamosas/diagnóstico por imagem , Neoplasias da Mama/patologia , Neoplasias da Mama/cirurgia , Carcinoma de Células Escamosas/patologia , Carcinoma de Células Escamosas/cirurgia , Feminino , Humanos , Mamografia , Mastectomia Radical Modificada , Metaplasia/patologia , Pessoa de Meia-Idade
3.
Frontiers (Boulder) ; 20(3): 83-107, 1999.
Artigo em Inglês | MEDLINE | ID: mdl-20552743
4.
Ann Biol Clin (Paris) ; 47(6): 340-5, 1989.
Artigo em Francês | MEDLINE | ID: mdl-2571317

RESUMO

Urinary excretion of three enzymes of different subcellular location in kidney tissue, alanine aminopeptidase (AAP), gammaglutamyltransferase (GGT), N acetyl-beta-D glucosaminidase (NAG), was carried out in 79 healthy adults and 108 healthy children and in 69 adults with various therapies: antibiotics (32 cases), non steroidal anti-inflammatory drugs (NSAIDs) (22 cases), cisplatinum (12 cases) and cyclosporine (3 cases). A circadian rhythm has been shown in children. In patients treated with antibiotics, the importance and duration of the increased enzymes urinary excretion were variable but the excretion of AAP was always higher than that of GGT and NAG. Short term therapies by NSAIDs were without influence on enzymuria but long term therapies produced a moderate increase of NAG excretion. Enzymuria increased immediately after cisplatinum administration and decreased after each daily dose, except in patients with previously high creatininemia. Cyclosporine induced a slight increase in AAP and NAG excretion. Enzymuria, thus, increased early reflecting a toxic effect of the drug at the cellular level whereas creatininemia increase, marker of renal fonctionnal insufficiency, occurs only occasionally and lately.


Assuntos
Acetilglucosaminidase/urina , Aminopeptidases/urina , Hexosaminidases/urina , Rim/efeitos dos fármacos , gama-Glutamiltransferase/urina , Adulto , Idoso , Idoso de 80 Anos ou mais , Antibacterianos/efeitos adversos , Anti-Inflamatórios não Esteroides/efeitos adversos , Antígenos CD13 , Criança , Pré-Escolar , Ritmo Circadiano , Cisplatino/efeitos adversos , Ciclosporinas/efeitos adversos , Humanos , Rim/enzimologia , Pessoa de Meia-Idade , Estudos Multicêntricos como Assunto
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