1.
Chem Commun (Camb)
; (19): 1974-5, 2001 Oct 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12240246
RESUMO
beta-Cyclodextrin catalyses for the first time the asymmetric reduction of alpha-azido aryl ketones to corresponding alcohols of great significance using sodium borohydride in water. The azido group appeared to be the best fit among various groups studied. This asymmetric reduction using water as solvent overcomes many of the drawbacks in the existing methodologies.