1.
Org Biomol Chem
; 21(24): 4962-4966, 2023 Jun 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37272266
RESUMO
An expeditious and regioselective approach towards the construction of a spiro-chroman motif is described. Quinone methides underwent a PTSA catalyzed annulation with 2-benzylidene dithiolanes to afford spiro-chroman dithiolanes in high yields. The synthetic versatility of the dithiolane motif was demonstrated by converting the adduct to coumarin, 3,4-dihydrocoumarin and chroman derivatives.