RESUMO
INTRODUCTION: Burns can have a considerable negative impact on physical and psychosocial functioning that affects the quality of life. The physical and psychological manifestations may compromise the quality of life of burned patients. The aim is to assess health-related quality of life and associated factors among burn patients at Amhara regional state governmental referral hospitals, Northwest Ethiopia, 2020. METHODS: Institution-based cross-sectional study was conducted from June 01 to July 15, 2020, in Amhara National regional state governmental referral hospitals. Systematic random sampling technique was used, and data were collected using structured Burn Specific Health Scale Brief Questionnaire through face-to-face interview and document review from patients time since burn 15 days and above. Data were entered into Epidata, and analysis was done by SPSS version 25. Descriptive statistics were computed, and binary logistic regression analysis was used to determine the association between the dependent and independent variables. Variables with a p-value of ≤0.05 in the multivariable analysis were considered statistically significant. RESULTS: Of 423 study participants, 95.7% responded completely. Among the respondents, 58.8% (group mean and median of 18.38 and 21) for physical domain and 57% (group mean and median of 44.73 and 53) for generic domains had a poor health-related quality of life. Overall poor health-related quality of life was 57.5% with a mean of 63.12. Third-degree burn, exposed burnt body part, total body surface area burned ≥20%, having an amputation and having a co-morbid illness with (P = 0.001) were associated with poor health-related quality of life. CONCLUSION AND RECOMMENDATION: This study revealed that more than half of the burn survivors had poor health-related quality of life. There shall be strengthened long-term physical and psychosocial domains (generic) intervention for burn survivors by giving more concern for those with the identified risk factors.
RESUMO
INTRODUCTION: Globally, tuberculosis takes the first rank for the ill-health of people living with HIV/AIDS. Despite the favorable outcome of antiretroviral therapy, the risk of tuberculosis remains higher among HIV patients. This obliges to identify factors for its occurrence and further prevention of drug-resistant tuberculosis. There is a contradiction between different studies and studies conducted in Ethiopia studied poorly the association between adherence to antiretroviral therapy and viral load with tuberculosis. Studies conducted in the study area were limited to cross-sectional study design. Therefore, this study claimed to identify factors determining the occurrence of tuberculosis after initiation of antiretroviral therapy. METHODS: This study was conducted at Dessie Referral Hospital by using a case-control study design on a sample of 565 with a control: case ratio of 3:1. Participants from controls were selected by systematic random sampling and from cases by consecutive random sampling. The data were collected by interviewing through structured questionnaires and from the medical record. The data were entered into Epi data version 3.1. In the multivariable analysis, variables with a P-value of ≤0.05 were anticipated as independent determinant factors. RESULT: Patients without separate kitchen (AOR: 3.547, 95% CI: 2.137, 5.888), having opportunistic infection (AOR: 3.728, 95% CI: 2.058, 6.753), CD4 count of <350 cells/mm3 (AOR: 3.383, 95% CI: 1.520, 7.528), baseline WHO stage III (AOR: 3.321, 95% CI: 1.688, 6.534) or IV (AOR: 2.900, 95% CI: 1.251, 6.722), don't taking IPT (AOR: 3.701, 95% CI: 2.228, 6.147) and those who were poorly adherent (AOR: 2.626, 95% CI: 1.272, 5.423) or moderately adherent (AOR: 3.455, 95% CI: 1.885, 6.335) to anti-retroviral therapy were more likely to develop tuberculosis after anti-retroviral therapy initiation. CONCLUSION: Poor housing conditions, having an opportunistic infection, low CD4 count, starting ART at the advanced HIV stage, don't take IPT, and being poorly adherent to antiretroviral therapy were associated with the occurrence of TB after initiation of ART. The institution should screen for TB as early as possible and strictly follow their drug adherence.
