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5.
Ann Nutr Metab ; 30(3): 149-65, 1986.
Artigo em Francês | MEDLINE | ID: mdl-3521448

RESUMO

The levels of galactose and galactitol in the sera of 6 young adults after ingestion of 0.25 g/kg of galactose alone or with the same quantity of glucose were studied. The results showed that: glucose decreased significantly the galactosemia and galactitolemia observed after ingestion of galactose alone; repeated consumption on 4 consecutive days of galactose alone induced an increase in galactosemia, and more significantly in galactitolemia. The addition of glucose to galactose in the same conditions abolished these effects.


Assuntos
Galactitol/sangue , Galactosemias/sangue , Glucose/farmacologia , Álcoois Açúcares/sangue , Adulto , Glicemia/metabolismo , Feminino , Galactose/farmacologia , Humanos , Insulina/sangue , Masculino
6.
Clin Sci (Lond) ; 66(6): 717-23, 1984 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-6723208

RESUMO

Fluorescence polarization of diphenylhexatriene embedded in membranes was used as an index of 'microviscosity' in platelets and erythrocyte ghosts of spontaneously hypertensive rats of the Okamoto-Aoki strain (SHR), Wistar-Kyoto strain (WKY) and of the hypertension-prone and -resistant Sabra strains (SBH and SBN ), and the original Sabra strain (SB). Microviscosity was increased both in erythrocyte ghosts and platelet membranes of male but not female SHR rats compared with WKY rats and in hypertension-prone Sabra rats compared with the original Sabra rats. Acute and chronic salt loading increased the microviscosity of platelet membranes in all strains of rats but had no effect on the erythrocyte membranes. Microviscosities of vesicles made of lipids extracted from SHR and WKY erythrocyte ghosts were similar. This supports the hypothesis that membrane proteins play a major role in the differences in microviscosity observed in SHR rats.


Assuntos
Plaquetas/fisiologia , Membrana Eritrocítica/fisiologia , Hipertensão/sangue , Animais , Membrana Celular/fisiologia , Colesterol/sangue , Difenilexatrieno , Feminino , Polarização de Fluorescência , Hipertensão/genética , Masculino , Fluidez de Membrana , Lipídeos de Membrana/sangue , Proteínas de Membrana/sangue , Ratos , Sódio/sangue , Viscosidade
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