Assuntos
Corticosteroides/efeitos adversos , Anti-Inflamatórios/efeitos adversos , Toxidermias/etiologia , Fatores Imunológicos/efeitos adversos , Administração Cutânea , Corticosteroides/administração & dosagem , Corticosteroides/química , Anti-Inflamatórios/química , Diagnóstico Diferencial , Relação Dose-Resposta a Droga , Toxidermias/diagnóstico , Humanos , Hidrocortisona/administração & dosagem , Hidrocortisona/efeitos adversos , Hidrocortisona/química , Fatores Imunológicos/administração & dosagem , Fatores Imunológicos/química , Testes do Emplastro , Fatores de RiscoRESUMO
Acquired ichthyosis and livedoid palmoplantar keratoderma have rarely been described in systemic lupus erythematosus (SLE). In the first case, a 51-year-old man presented with generalized acquired ichthyosis associated with renal glomurelosclerosis and neurolupus. rituximab allowed total resolution of the acquired ichthyosis. A livedoid palmoplantar keratoderma was observed in a 45-year-old woman as the initial clinical manifestation of a systemic lupus erythematosus associated with Raynaud's phenomenon, photosensitivity and inflammatory polyarthralgia. Although the pathophysiology is not well-defined, these unusual cutaneous manifestations should be considered by physicians when diagnosis of SLE is suspected.
Assuntos
Ictiose/diagnóstico , Ceratodermia Palmar e Plantar/diagnóstico , Lúpus Eritematoso Sistêmico/diagnóstico , Diagnóstico Diferencial , Feminino , Humanos , Ictiose/etiologia , Ceratodermia Palmar e Plantar/etiologia , Lúpus Eritematoso Sistêmico/complicações , Masculino , Pessoa de Meia-Idade , Dermatopatias/diagnósticoRESUMO
Cutaneous melanoma patients are usually young adults. The evolution into a nodular form darkens the prognosis because it increases the risk of metastasis occurrence. The only curative treatment is wide surgical excision when extension check is negative. We report a case of abdomino-pubic melanoma original by its amazing size, its spreading, both superficial and nodular, without metastasis, and its late occurrence to a senior patient. Curative management was performed with a plastic surgery technique: the abdominal plasty. The melanoma was removed with free margins and the patient was free of disease at six month. This report illustrates the interest of plastic surgery techniques in oncology. It also confirms that plastic surgeon forms an integral part of a multidisciplinary team managing patients with cutaneous melanoma.