Analysis of Soret and Dufour effects on radiative heat transfer in hybrid bioconvective flow of carbon nanotubes.

Numerous heat transfer applications, such as heat exchangers, solar trough collectors, and fields including food processing, material research, and aerospace engineering, utilize hybrid nanofluids. Compared to conventional fluids, hybrid nanofluids exhibit significantly enhanced thermal conductivity. The aim of this work is to explore flow and heat transmission features under of magneto-hydrodynamic bioconvective flow of carbon nanotubes over the stretched surface with Dufour and Soret effects. Additionally, comparative dynamics of the carbon nanotubes (SWCMT - MWCNT/C2H6O2 with SWCMT - MWCNT/C2H6O2 - H2O) flow using the Prandtl fluid model in the presence of thermal radiation and motile microorganisms has been investigated. Novel feature Additionally, the focus is also to examine the presence of microorganisms in mixture base hybrid nanofluid. To examine heat transfer features of Prandtl hybrid nanofluid over the stretched surface convective heating is taken into consideration while modeling the boundary conditions. Suitable similarity transform has been employed to convert dimensional flow governing equations into dimensionless equations and solution of the problem has been obtained using effective, accurate and time saving bvp-4c technique in MATLAB. Velocity, temperature, concentration and microorganisms profiles have been demonstrated graphically under varying impact of various dimensionless parameters such as inclined magnetization, mixed convection, Dufour effect, Soret effect, thermal radiation effect, and bioconvection lewis number. It has been observed that raising values of magnetization (0.5 ≤ M ≤ 4), mixed convection (0.01 ≤ λ ≤ 0.05) and inclination angle (0° ≤ α ≤ 180°) enhance fluid motion rapidly in Ethylene glycol based Prandtl hybrid nanofluid (SWCMT - MWCNT/C2H6O2) when compared with mixture base working fluid of carbon nanotubes SWCMT - MWCNT/C2H6O2 - H2O). Raising thermal radiation (0.1 ≤ Rd ≤ 1.7) and Dufour number (0.1 ≤ Du ≤ 0.19) values improves temperature profile. Moreover, a good agreement has been found between the current outcome and existing literature for skin friction outcomes.

Statistical computation for heat and mass transfers of water-based nanofluids containing Cu, Al2O3, and TiO2 nanoparticles over a curved surface.

Nanofluid is a specially crafted fluid comprising a pure fluid with dispersed nanometer-sized particles. Incorporation these nanoparticles into pure fluid results in a fluid with improved thermal properties in comparison of pure fluid. The enhanced properties of nanofluids make them highly sought after, in diverse applications, consisting of coolant of devices, heat exchangers, and thermal solar systems. In this study hybrid nanofluid consisting of copper, alumina and titanium nanoparticles on a curved sheet has investigated with impact of chemical reactivity, magnetic field and Joule heating. The leading equations have converted to normal equations by using appropriate set of variables and has then evaluated by homotopy analysis method. The outcomes are shown through Figures and Tables and are discussed physically. It has revealed in this study that Cu-nanofluid flow has augmented velocity, temperature, and volume fraction distributions than those of Al2O3-nanofluid and TiO2-nanofluid. Also, the Cu-nanofluid flow has higher heat and mass transfer rates than those of Al2O3-nanofluid and TiO2-nanofluid.

A numerical exploration of the comparative analysis on water and kerosene oil-based Cu-CuO/hybrid nanofluid flows over a convectively heated surface.

The fluid flow over an extending sheet has many applications in different fields which include, manufacturing processes, coating, thin film decomposition, heat and mass transfer, biomedical applications, aerospace engineering, environmental science, energy production. Keeping in mind these applications, the non-Newtonian hybrid nanofluid flow comprising of Cu and CuO nanoparticles over an extending sheet is analyzed in this work. Two different base fluids called kerosene oil and water have been incorporated. The sheet is considered to be thermally convective along with zero mass flux condition. The main equations of modeled problem have been transformed to dimensionless form by using similarity variables. The designed problem is evaluated computationally by using bvp4c Matlab function. Validation of the present results is also performed. The impacts of magnetic, Brownian motion, chemical reaction, suction and thermophoresis factors are analyzed and discussed in details. The outcomes of the present investigation declare that the kerosene oil-based hybrid nanofluid flow has greater velocity and concentration profiles than that of the water-based hybrid nanofluid flow. The water-based hybrid nanofluid has greater temperature distribution than that of kerosene oil-based hybrid nanofluid flow. The streamlines of the kerosene oil-based Newtonian and non-Newtonian hybrid nanofluid flows are more stretched than water-based Newtonian and non-Newtonian hybrid nanofluid flows.

A stratified flow of a non-Newtonian Casson fluid comprising microorganisms on a stretching sheet with activation energy.

A stratified flow may be seen regularly in a number of significant industrial operations. For instance, the stratified flow regime is typically used by gas-condensate pipelines. Clearly, only a limited set of working situations for which this flow arrangement is stable allow for the achievement of the stratified two-phase flow zone. In this paper, the authors are considered the laminar, steady and incompressible magnetohydrodynamic flow of a non-Newtonian Casson fluid flow past a stratified extending sheet. The features of bio-convection, Brownian motion, thermal radiation thermophoresis, heat source, and chemically reactive activation energy have been employed. The set of equations administered flow of fluid is converted into ordinary differential equation by suitable variables. A semi-analytical investigation of the present analysis is performed with homotopy analysis method. Endorsement of the current results with previous results is also investigated. The outcomes showed that the velocity distribution of the fluid flow lessens with higher Casson and magnetic factors. The temperature profiles of fluid flow shrinkage as the Prandtl number and Casson factor increase and enlarges with higher values of thermal radiation, magnetic, and Brownian motion factors. It is found that the growing thermophoretic and Brownian motion factors reduce the rate of thermal flow of the Casson fluid flow. In contrast, the increasing thermal stratification parameter increases the thermal flow rate of fluid.

Irreversibility analysis with hybrid cross nanofluid of stagnation point and radiative flow ( T i O 2 + C u O ) based on engine oil past a stretchable sheet.

The present study addressed the physical significance of the entropy generation for the mixed convection time-dependent flow of cross-hybrid nanoliquid due to the stretched surface at a stagnation point. The Plot for heat transport is discoursed by applying the role of thermal radiation under convective conditions. For hybrid nanofluid, engine oil is used as a base liquid with copper (II) oxide C u O and titanium dioxide T i O 2 nanoparticles. The existing model is framed in the highly partial differential equation system. The governing equations have been transformed into a set of ODS's using a similar scaling operation. Following this, the resulting ODEs are solved numerically through the BVP4c. The primary goal of this research is to analyze the results of varying the stretching ratio parameter ( λ ), Weissenberg parameter ( W e ), thermal radiation ( R d ), and Biot number ( B i ) for both pure T i O 2 and CuO +  T i O 2 / E O hybrid nanofluid, on the velocity, temperature, drag force, heat transfer as well as entropy generation, and Bejan number was studied. A drop in velocity is observed with increasing values of the W e and upsurge in velocity for rising value of unsteady parameter ( A ), while increasing values of both of these parameters are associated with rising temperatures. Copper and titanium oxide nanoparticles are used to increase Engine oil (EO) thermal enactment, making it a more useful base fluid. Further, some significant industrial and engineering applications are related to the present problem discourse.

Casson nanoliquid film flow over an unsteady moving surface with time-varying stretching velocity.

Present study explains about unsteady Casson nanoliquid film flow over a surface moving with velocity [Formula: see text]. The governing momentum equation is reduced to ODE by using corresponding similarity transformation, which is then tackled by employing numerical technique. The problem is analysed for both two-dimensional film flow and axisymmetric film flow. The exact solution is derived which satisfies the governing equation. It is noted that solution exists only for a specified scale of the moving surface parameter [Formula: see text]. ie., [Formula: see text] for two-dimensional flow and [Formula: see text] for axisymmetric flow. The velocity increases first and reaches the maximum velocity and then decreases to the boundary condition. Streamlines are also analysed for both axisymmetric and two-dimensional flow patterns by considering the stretching ([Formula: see text]) and shrinking wall conditions ([Formula: see text]). Study has been made for large values of wall moving parameter [Formula: see text]. The aim of this investigation is to analyse the Casson nanoliquid film flow which finds applications in industries like coating of sheet or wire, laboratories, painting, many more.

MHD Casson fluid flow with Navier's and second order slip due to a perforated stretching or shrinking sheet.

The present work discusses the laminar boundary layer flow of an electrically conducting Casson fluid due to a horizontal perforated sheet undergoing linear shrinking/stretching with mass transpiration. Navier's slip and second-order slip conditions are also imposed on the flow. The system is subjected to a transverse magnetic field. The non-Newtonian flow under consideration obeys the rheological equation of state due to the Casson model. The PDEs governing the bounder layer flow is reduced to a nonlinear boundary value problem in ODEs by utilizing appropriate similarity transformations and are expressed analytically. The similarity solution is found to be a function of the Casson parameter, magnetic parameter, mass suction/injection parameter, and the first/second-order slip parameters. Such a solution is either unique, or dual solutions exist in a region defined by the mass transfer induced slip parameter. The results of the present work are found to be an increase of the magnetic effects resulting in expansion of the unique solution region and contraction of the dual solution region for the flow due to the induced Lorentz force. In the unique solution region, an increase in magnitudes of mass suction induced slip and the first/second-order slip parameters result in a reduction of the wall shear stress in the shrinking sheet, while the wall shear stress with mass suction increases with the Casson and the magnetic effects. Similar results exist for the stretching sheet case with mass suction. However, only unique similarity solutions exist only for the case of stretching sheets with mass injection. The current work is a generalization of the classical works of Crane (1970) and Pavlov (1974) for a stretching sheet. Mass suction/injection induced slip enhances and achieves a dominant flow driven by reversing the flow direction of the moving sheet, which allows an adjacent flow against the sheet. The findings have possible industrial applications in fluid-based systems including stretchable/shrinkable things, automated cooling systems, power generation, microelectronics, and present new results to the problem.

Features of entropy optimization on MHD couple stress nanofluid slip flow with melting heat transfer and nonlinear thermal radiation.

Numerical analysis is performed for magnetohydrodynamics (MHD) couple stress nanofluid flow over a stretching sheet with melting and nonlinear radiation. The second law of thermodynamics is also incorporated with first-order slip. Nanofluid characteristics for thermophoresis and Brownian moments are encountered. The system that comprises differential equations of partial derivatives is remodeled into the system of differential equations via similarity transformations and then solved numerically through the Runge-Kutta-Fehlberg fourth-fifth (RKF-45) order technique. The physical parameters, which emerges from the derived system are discussed in graphical format. The significant outcomes of the current investigation are that the velocity field decays for a higher magnetic parameter. Another, important outcome of the study is both temperature and concentration are increasing functions of the first-order slip. Nusselt and Sherwood numbers are decreasing with an increase in magnetic strength. Further, Bejan number augment due to enhancement in the first-order slip and couple stress fluid parameters whereas a differing tendency is shown for magnetic and radiation parameters.

Impact of heat generation/absorption of magnetohydrodynamics Oldroyd-B fluid impinging on an inclined stretching sheet with radiation.

In this paper, we have investigated thermally stratified MHD flow of an Oldroyd-B fluid over an inclined stretching surface in the presence of heat generation/absorption. Similarity solutions for the transformed governing equations are obtained. The reduced equations are solved numerically using the Runge-Kutta Fehlberg method with shooting technique. The influences of various involved parameters on velocity profiles, temperature profiles, local skin friction, and local Nusselt number are discussed. Numerical values of local skin friction and local Nusselt number are computed. The significant outcomes of the study are that the velocity decreases when the radiation parameter [Formula: see text] is increased while the temperature profile is increased for higher values of radiation parameter [Formula: see text] in case of opposing flow, moreover, growth in Deborah number [Formula: see text] enhance the velocity and momentum boundary layer. The heat transfer rate is decrease due to magnetic strength but increase with the increased values of Prandtl and Deborah numbers. The results of this model are closely matched with the outputs available in the literature.

Mass Transpiration in Nonlinear MHD Flow Due to Porous Stretching Sheet.

Motivated from numerous practical applications, the present theoretical and numerical work investigates the nonlinear magnetohydrodynamic (MHD) laminar boundary layer flow of an incompressible, viscous fluid over a porous stretching sheet in the presence of suction/injection (mass transpiration). The flow characteristics are obtained by solving the underlying highly nonlinear ordinary differential equation using homotopy analysis method. The effect of parameters corresponding to suction/injection (mass transpiration), applied magnetic field, and porous stretching sheet parameters on the nonlinear flow is investigated. The asymptotic limits of the parameters regarding the flow characteristics are obtained mathematically, which compare very well with those obtained using the homotopy analysis technique. A detailed numerical study of the laminar boundary layer flow in the vicinity of the porous stretching sheet in MHD and offers a particular choice of the parametric values to be taken in order to practically model a particular type of the event among suction and injection at the sheet surface.

Copper(II) complexes with highly water-soluble L- and D-proline-thiosemicarbazone conjugates as potential inhibitors of Topoisomerase IIα.

Two proline-thiosemicarbazone bioconjugates with excellent aqueous solubility, namely, 3-methyl-(S)-pyrrolidine-2-carboxylate-2-formylpyridine thiosemicarbazone [L-Pro-FTSC or (S)-H2L] and 3-methyl-(R)-pyrrolidine-2-carboxylate-2-formylpyridine thiosemicarbazone [D-Pro-FTSC or (R)-H2L], have been synthesized and characterized by elemental analysis, one- and two-dimensional (1)H and (13)C NMR spectroscopy, and electrospray ionization mass spectrometry. The complexation behavior of L-Pro-FTSC with copper(II) in an aqueous solution and in a 30% (w/w) dimethyl sulfoxide/water mixture has been studied via pH potentiometry, UV-vis spectrophotometry, electron paramagnetic resonance, (1)H NMR spectroscopy, and spectrofluorimetry. By the reaction of copper(II) acetate with (S)-H2L and (R)-H2L in water, the complexes [Cu(S,R)-L] and [Cu(R,S)-L] have been synthesized and comprehensively characterized. An X-ray diffraction study of [Cu(S,R)-L] showed the formation of a square-pyramidal complex, with the bioconjugate acting as a pentadentate ligand. Both copper(II) complexes displayed antiproliferative activity in CH1 ovarian carcinoma cells and inhibited Topoisomerase IIα activity in a DNA plasmid relaxation assay.

Does malaoxon play a role in the geno- and cytotoxic effects of malathion on human choriocarcinoma cells?

This investigation was undertaken to elucidate whether the active metabolite of malathion, malaoxon, has any role in exerting cyto- and genotoxic effects for human choriocarcinoma (JAR) cell line which is an acceptable model for human placental cells. Gas chromatography-mass spectrometry (GC-MS) analysis were separately performed on the cell compartment and supernatant cell culture medium after subjecting the cell line to different malathion concentrations (10-400 µg/mL) and for various incubation periods (0.5 to 24 hours). GC-MS analysis showed that the sonication performed for the disruption of the cells did not cause the chemical change of malathion. The uptake of malathion by the cells was relatively fast. However, the presence of malaoxon, even in trace amounts, could not be confirmed either in samples originating from disrupted cells or in the cell culture medium. Although the hydrolysis of malaoxon occurred in the culture medium, this degradation process could not be counted as a reason for the absence of malaoxon. Since both malathion and malaoxon standard compounds could be accurately detected and distinguished by the applied liquid-liquid extraction and GC-MS methods, one can conclude that, in the case of JAR cells, the parent compound, (i.e. malathion itself) is responsible for the observed in vitro cyto- and genotoxic effects. Our results indicate that the direct toxicity of malathion contributes to the complications of pregnancy observed for environmental malathion exposure.

Birefringence of cells grown in vitro and of mitotic chromosomes after staining with picrosirius red

Fibroblasts and neuroblastoma cells kept in monolayer cultures, as well as surface spreads of mitotic chromosomes, were stained with picrosirius red. Red staining (in normal light) and optical anisotropy of the stained structures (in polarized light) were observed intracellularly and in the chromosomes. The intracellular and extranuclear birefringence induced by staining with sirius red could not be abolished by digestion with collagenase prior to staining, or by treatments used to disrupt microtubules (vinblastine, colcemid) or microfilaments (cytochalasin B). We therefore propose that the parallelly-arranged intermediate filaments are responsible for the optical anisotropy induced by sirius red staining in these cells. In addition, the spatially oriented scaffold of chromosomes can be detected by sirius red-induced birefringence. These data argue against the collagen-specificity of picrosirius red staining and of the birefringence induced by this technique. Our results also suggest that picrosirius red staining combined with polarized light microscopy can be used to study the spatial orientation pattern of the intermediate filaments and chromosome scaffold.

Alteration of tight and adherens junctions on 50-Hz magnetic field exposure in Madin Darby canine kidney (MDCK) cells.

Adherens (AJ) and tight junctions (TJ), as integrated parts of the junctional complex, are multifunctional specialized regions of the cell membrane in epithelial cells. They are responsible for cell-to-cell interactions and also have great importance in cellular signaling processes including Wnt protein-mediated signals. As electromagnetic field (EMF) exposure is known to cause alterations in the function as well as supramolecular organization of different cell contacts, our goal was to investigate the effect of 50-Hz magnetic field (MF) exposures on the subcellular distribution of some representative structural proteins (occludin, beta-catenin, and cadherin) found in AJ and TJ. Additionally, cellular beta-catenin content was also quantified by Western blot analysis. 50-Hz MF exposures seemed to increase the staining intensity (amount) of occludin, cadherins, and beta-catenin in the junctional area of MDCK cells, while Western blot data indicated the quantity of beta-catenin was found significantly decreased at both time points after EM exposures. Our results demonstrate that MF are able to modify the distribution of TJ and AJ structural proteins, tending to stabilize these cell contacts. The quantitative changes of beta-catenin suggest a causative relationship between MF effects on the cell junctional complex and the Wnt signaling pathway.

[Cellular biology and public health]. / Sejtbiológia és népegészségügy.

Within the framework of the National Research and Development Program No. 1/016 /2001 the authors determined the population levels of ionizing and nonionizing radiations, elaborated the system of assays for detection of biological effects including dose-effect relationships, studied the roles of protective and sensitizing factors in the effect modification. The radium content of building materials were determined as well as the indoor radon activity concentrations and the magnetic induction fields around household equipment operating with 50 Hz. Biological dosimetry techniques were categorized according to the indication time. In addition, radiation sensitivity of intracellular antioxidant enzymes and the antioxidant capacity of blood sera were measured.

Long-term persistence of chromosome aberrations in uranium miners.

Chromosome aberration analyses were performed on blood samples from 165 active underground uranium miners between 1981 and 1985. After decommissioning the mine in 1997 chromosome aberration analyses were also included in the medical laboratory investigations of health conditions of 141 subjects between 1998 and 2002 within the framework of a follow-up-study. The numerical data are presented as functions of the exposure categories expressed in working level month up to 600. In the active groups the dicentric level was 7 to 12 times higher than in the unexposed population, the acentrics also higher with more than an order of magnitude, the frequency of total aberrations--including dicentrics, acentrics, rings, deletions, minits and numerical aberrations, i.e. both chromatid and chromosome type of aberrations were also well above the control level. In the group of former uranium miners although there were slight decreases in the dicentrics after 8 to 25 yr, the values were not significantly different from the values of active miners. The frequency of deletions was also maintained in the post-mining period. The frequency of acentrics, however, decreased significantly, but even the lowest values remained 2-3 times higher than the values in the unexposed population.The possibility is suggested that for the long-term persistence of cytogenetic alterations the permanent production and presence of clastogenic factors might be responsible. The comparison of the two datasets suggest a long-term persistence of cytogenetic alterations above the population average values in a large fraction of persons investigated.