[Endocarditis with negative blood cultures and immunological alterations: a grand challenge]. / Endocardite com hemoculturas negativas e alterações imunológicas: um grande desafio.

Subacute Infectious endocarditis can present immunological phenomena and extracardiac manifestations such as anemia and musculoskeletal pain which can mimic rheumatological disease. It is related a case on infectious endocarditis presenting symptomatology similar to Polymyalgia Rheumatica despite acute nephritis after antibiotic. The differential diagnostic features of Libman-Sacks endocarditis versus infective endocarditis are discussed.