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Comput Methods Biomech Biomed Engin ; 27(6): 736-750, 2024 May.
Artigo em Inglês | MEDLINE | ID: mdl-37071538

RESUMO

Mechanical circulatory support (MCS) devices can bridge the gap to transplant whilst awaiting a viable donor heart. The Realheart Total Artificial Heart is a novel positive-displacement MCS that generates pulsatile flow via bileaflet mechanical valves. This study developed a combined computational fluid dynamics and fluid-structure interaction (FSI) methodology for simulating positive displacement bileaflet valves. Overset meshing discretised the fluid domain, and a blended weak-strong coupling FSI algorithm was combined with variable time-stepping. Four operating conditions of relevant stroke lengths and rates were assessed. The results demonstrated this modelling strategy is stable and efficient for modelling positive-displacement artificial hearts.


Assuntos
Transplante de Coração , Próteses Valvulares Cardíacas , Humanos , Modelos Cardiovasculares , Doadores de Tecidos , Fluxo Pulsátil , Desenho de Prótese
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