[Salivary immunoglobulin A (sIgA) kinetics in young adults with an average or excellent aerobic capacity before and after a cardiopulmonary graded exercise test]. / Cinética de la inmunoglobulina-A salival (IgAs) en adultos jóvenes con capacidad aeróbica promedio o excelente antes y después de una prueba de esfuerzo máximo.

BACKGROUND: Aim: To compare the concentration of secretory immunoglobulin-A (sIgA) in young adults with average or excellent aerobic capacity before and after a cardiopulmonary graded exercise test. METHODS: Participants were nine apparently healthy physically active males (Mean age = 21.3 ± 2.1 yr.), randomly allocated in two groups based on their VO2max: a) average aerobic capacity (AEC, n = 5) or b) excellent aerobic capacity (EAC, n = 4). Participants performed the Bruce protocol to determine their aerobic capacity. The sIgA was measured before the test, immediately after the test and 60-, 120-, 240-, and 1440-min after the test. RESULTS: Mixed factorial 2 x 6 ANOVA indicated no significant interactions between groups and measurements (p = 0.956), and main effect groups on sIgA (AEC = 85.4 ± 19.3 µg/mL vs. EAC = 79.2 ± 21.5 µg/mL, p = 0.836). Tukey's post hoc analysis revealed significant differences measurement obtained immediately after the test and between the initial measurement (p = 0.020), 60-min (p = 0.030), 240-min (p = 0.016), and 1440-min (p = 0.028) following the test. CONCLUSION: There is no change in sIgA kinetics depending on the aerobic capacity of the participants following an aerobic capacity cardiopulmonary graded exercise test.

Cinética de la inmunoglobulina-A salival (IgAs) en adultos jóvenes con capacidad aeróbica promedio o excelente antes y después de una prueba de esfuerzo máximo / Salivary immunoglobulin A (sIgA) kinetics in young adults with an average or excellent aerobic capacity before and after a cardiopulmonary graded exercise test

Background: Aim: To compare the concentration of secretory immunoglobulin-A (sIgA) in young adults with average or excellent aerobic capacity before and after a cardiopulmonary graded exercise test. Methods: Participants were nine apparently healthy physically active males (Mean age = 21.3 ± 2.1 yr.), randomly allocated in two groups based on their VO2max: a) average aerobic capacity (AEC, n = 5) or b) excellent aerobic capacity (EAC, n = 4). Participants performed the Bruce protocol to determine their aerobic capacity. The sIgA was measured before the test, immediately after the test and 60-, 120-, 240-, and 1440-min after the test. Results: Mixed factorial 2 x 6 ANOVA indicated no significant interactions between groups and measurements (p = 0.956), and main effect groups on sIgA (AEC = 85.4 ± 19.3 μg/mL vs. EAC = 79.2 ± 21.5 μg/mL, p = 0.836). Tukey's post hoc analysis revealed significant differences measurement obtained immediately after the test and between the initial measurement (p = 0.020), 60-min (p = 0.030), 240-min (p = 0.016), and 1440-min (p = 0.028) following the test. Conclusion: There is no change in sIgA kinetics depending on the aerobic capacity of the participants following an aerobic capacity cardiopulmonary graded exercise test.

Introducción. Objetivo: Comparar la cinética en la concentración de inmunoglobulina A salival (IgAs) en adultos jóvenes con capacidad aeróbica promedio (n: 5) o excelente (n: 4) antes y después de una prueba de esfuerzo. Método: 9 adultos jóvenes (edad 21,3 ± 2,1), divididos de acuerdo su VO2máx, realizaron una prueba de esfuerzo mediante el protocolo de Bruce. La concentración de IgAs fue determinada mediante el Salimetrics IgA Kit®, evaluando inicial, inmediatamente finalizada la prueba, +60, +120, +240, +1.440 min. Resultados: La prueba ANOVA 2x6 mixta indicó que no existieron interacciones significativas entre grupos y mediciones (p = 0,956). Tampoco se encontró una diferencia significativa en la media de IgAs en los grupos (Promedio = 85,4 ± 19.3 μg/mL vs Excelente=79,2 ± 21.5 μg/mL, p = 0,836). Independientemente de las mediciones, el análisis post hoc de Tukey indicó que las diferencias se encontraron en la medición obtenida inmediatamente después de la prueba y entre la medición inicial (p: 0,020), la medición obtenida 60 min (p: 0,030), 240 min (p: 0,016) y 1.440 min (p = 0,028) posteriores a la prueba. Conclusión: Los datos encontrados sugieren que no hay un cambio en la concentración de IgAs a través del tiempo en función de la capacidad aeróbica de los participantes.

Moderate intensity exercise is associated with decreased angiotensin-converting enzyme, increased ß2-adrenergic receptor gene expression, and lower blood pressure in middle-aged men.

PURPOSE: The purpose of the current study was to characterize the role of aerobic exercise in the gene expression of the angiotensin-converting enzyme (ACE) and the ß2-adrenergic receptor (ADRB2) in untrained men. METHODS: Twenty untrained middle-aged men were randomly assigned to exercise (Exe) and control (Con) groups. The Exe group performed aerobic exercises for eight weeks. ACE mRNA and ADRB2 mRNA were determined by PCR. RESULTS: The expression of ACE in week 4 and in the Exe group decreased significantly (p < .001). ADRB2 in the Exe group, in week 4 and in week 8, was markedly higher, and blood pressure was significantly lower than in the Con group (p < .001). In the Con group ADRB2 mRNA decreased. CONCLUSION: These results suggest that moderate intensity exercise promotes the leukocyte expression of gene markers that may affect blood pressure by improving cardiovascular fitness levels in middle-aged men.

Comparison of agility and dynamic balance in elderly women with endomorphic mesomorph somatotype with presence or absence of metabolic syndrome / Comparación de la agilidad y equilibrio dinámico en mujeres adultas mayores con somatotipo mesomorfo endomorfico y presencia o ausencia de síndrome metabólico

Physical function declines in efficiency with advancing age, contributing to disability. Furthermore, metabolic syndrome is a common illness in elderly populations, somatotayping is a technique for description of the physique and can establish a relation with performance and pathology. The aim of this work was to compare the agility, dynamic balance in elderly women with endomorphic mesomorph somatotype with presence or absence of metabolic syndrome. A sample of 18 volunteers was obtained (age 66.5+/-4.7 years old), all were elderly sedentary women. They were assessed whit anthropometric variables in accordance with ISAK protocol in order to determine Heath & Carter somatotype; presence of metabolic syndrome they were evaluated according with the NCEP ATP-III, the agility and dynamic balance was assessed with the functional test Time Up and Go (TUGT). Mean of somatotype in subjects with absence or presence of metabolic syndrome was 6.2-7.9-0.2 and 6.5-8.7-0.1 respectively; Shapiro­Wilk test checked the normality of the distribution in the functional test Time Up and Go, in the group with absence or presence of metabolic syndrome, based on its normality distribution for the intergroup comparison, the Student t test was applied, the significance level, utilized was 95 percent (P , 0.05) for the sample assessed without metabolic syndrome, the execution time of the functional test TUGT was better in spite of the same somatotype intergroup. The pathological components of metabolic syndrome can be related whit dysfunctional mobility in elderly women.

Conforme la edad progresa, se presenta una pérdida en la funcionalidad física del ser humano, contribuyendo al deterioro de su autonomía funcional, además el síndrome metabólico (SM) es un padecimiento común en poblaciones de adultos mayores. El somatotipo es una técnica utilizada para describir la forma del físico en diferentes tipos de poblaciones que puede establecer una relación con su rendimiento físico y patologías. El objetivo de este trabajo fue comparar la agilidad y equilibrio dinámico en adultas mayores con un somatotipo mesomorfo-endomorfico con presencia o ausencia de SM. Fue reclutada una muestra de 18 mujeres adultas mayores sedentarias (edad promedio de 66.5+/-4.7 años). Las variables antropométricas fueron valoradas utilizando los lineamientos establecidos por ISAK y se determinó el índice morfológico del somatotipo por el procedimiento de Heath & Carter. La presencia de SM fue evaluada de acuerdo al NCEP ATP-III, la agilidad y equilibrio dinámico fue medido mediante el test funcional de Timed up and go (TUGT). La media del somatotipo en las sujetos con ausencia y presencia de SM fue de 6.2-7.9-0.2 y 6.5-8.7-0.1 respectivamente; el test de Shapiro­Wilk fue utilizado para observar la normalidad de la distribución de los datos en el test de funcionalidad (TUGT)de ambos grupos, ya comprobada la normalidad de los datos, se aplicó la prueba t de Student con el nivel de significancia 95 por ciento (P , 0.05), comprobando que el grupo con ausencia de SM presentó una mejor agilidad y equilibrio dinámico. Es posible que los componentes patológicos del SM puedan estar relacionados con una pérdida de autonomía funcional en mujeres adultas mayores.