RESUMO
Los criterios de evaluación cefalométrica empleados para determinar el grado de compromiso medio facial en pacientes con labio y paladar hendido (L.P.H.) han dependido principalmente de la proyección del punto A con respecto a la base craneal anterior, el cual sólo define el comportamiento anteroposterior de la base ósea maxilar. El análisis de la proyección espacial del complejo malar en pacientes con labio y paladar hendido es importante para el diagnóstico y plan de tratamiento ortodóntico-quirúrgico. Esta investigación tiene como propósito establecer el comportamiento de la región malar en los tres planos del espacio, por medio de radiografías diagnósticas convencionales. Se determinaron medidas de frecuencia y tendencia central y análisis de varianza a las siguiente medidas lineales y angulares: cefálica (SNO, NOA, O_Fr); P-A (RMS-Za derecha e izquierda), submentovertex (distancia entre la tangente anterior del malar derecho e izquierdo con la tangente anterior del agujero occipital y la diferencia entre ellos, la tangente externa del malar derecho e izquierdo con el plano RMS, diferencia entre ellos). Del estudio se concluye que el complejo malar es más retrusivo en el plano sagital, más inferior en el plano vertical y menos expresivo transversalmente en pacientes con labio y paladar hendido. No se encontró diferencias significativas con respecto a la variable sexo.
Assuntos
Humanos , Masculino , Pré-Escolar , Adolescente , Feminino , Criança , Cefalometria , Fenda Labial , Fissura Palatina , Zigoma , Assistência Odontológica para Crianças/métodos , Fissura Palatina , Colômbia , Epidemiologia Descritiva , Faculdades de Odontologia , Fenda Labial/epidemiologia , Órbita/anatomia & histologia , Órbita , Valores de Referência , Simulação de Ambiente Espacial , Interpretação Estatística de Dados , ZigomaRESUMO
Posttraumatic aneurysms of the proximal intracranial internal carotid artery are rare. A case is presented in which the evolution and regression of such an aneurysm is documented by computed tomography as well as by arteriography. The coexistence of a proximal dissection of the cervical carotid artery probably contributed to the growth of the aneurysm.
Assuntos
Doenças das Artérias Carótidas/diagnóstico por imagem , Aneurisma Intracraniano/diagnóstico por imagem , Adulto , Doenças das Artérias Carótidas/etiologia , Lesões das Artérias Carótidas , Angiografia Cerebral , Humanos , Aneurisma Intracraniano/etiologia , Masculino , Hemorragia Subaracnóidea/etiologia , Tomografia Computadorizada por Raios XRESUMO
The development of a transplantable model brain tumor in the neonatal dog, the adaptation of the tumor to tissue culture, and the successful growth of the tumor in adult mongrel dogs has been adapted to producing similar tumors in the thoracic spinal cord of the adult dog. Ten adult dogs, weighing 4 to 25.4 kg each, were subjected to formal laminectomy. The tumor cell suspension was injected by hand with a Hamilton syringe at two or three sites over a distance of 1 cm; each site received an injection volume to 0.02 to 0.05 cc of the cell suspension after the dura had been opened. Immediately after injection the field was copiously irrigated and the puncture area sealed with a single drop of ethyl cyanoacrylate. Tumor cells for injection were obtained by thawing ampules stored at -195 degrees C in a mixture of 10% dimethyl sulfoxide and RPMI 1640 culture medium. Cells were resuspended in Hank's balanced salt solution and 15% fetal calf serum on ice. Solutions had 90% cell viability, and animals received a dose in the range of 3 to 13 X 10(6) cells. Eight animals developed tumors and became paraparetic on the 9th to 14th postinjection day. Metrizamide myelography in three animals revealed complete blocks; two animals underwent spinal computerized tomography (CT) and demonstrated syringohydromyelia. Histology revealed the tumors to be highly vascular primitive neoplasms that invaded the surrounding cord. This spinal cord tumor model is large enough to be operated on, studied by CT and myelography, and subjected to pharmacological, electrophysiological, and blood flow study.
Assuntos
Cães , Transplante de Neoplasias , Neoplasias da Medula Espinal/fisiopatologia , Animais , Técnicas de Cultura , Modelos Biológicos , Radiografia , Neoplasias da Medula Espinal/diagnóstico por imagem , Neoplasias da Medula Espinal/patologiaRESUMO
A preclinical evaluation of the technical details and dosimetry for temporary high intensity 192Ir brain implants is presented. The canine brain was used for this quality assurance study in which direct in vivo dose measurements were done by thermoluminescent dosimetry (TLD rods). Precise and reproducible positioning of the TLD rods and 192Ir ribbons were assured by simple accessories which can be utilized in the clinical situation. The neurosurgical procedure for this non-routine interstitial implant of the brain, suitability of type and size of afterloading cannulas and facility for firmly anchoring them to the scalp, and comparison of measured doses with computer-predicted values are details assured by the canine study. Agreement between the in vivo determination and computer-generated doses was consistently in the range 2-5%. Data derived from this preclinical evaluation are currently used in both stereotactic and non-stereotactic brain implants at our institution. Details are presented for the implant procedure, dose measurements and brachytherapy planning for multiple ribbons. The latter incorporates direct interaction on computed tomography (CT) images for a hypothetical patient case.
