Close association between oropharyngeal and rhinopharyngeal colonization with Staphylococcus aureus - clues to new insight of MRSA colonization of the oropharynx.

This study provides data on prevalence of Staphylococcus aureus in oropharynx, rhinopharynx and vestibulum nasi. Specimens were taken from these three pharyngeal sites in 346 patients and analysed for S. aureus. Abnormal pharyngeal findings and patient histories were recorded. S. aureus was found in 8.1%, 7.2% and 20.2% of all specimens from oropharynx, rhinopharynx and vestibulum nasi, respectively. A strong association between colonization of oropharynx and rhinopharynx was found, especially when vestibulum nasi was not colonized. These findings can be used in development of more effective meticillin-resistant Staphylococcus aureus decolonization regimes.