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Artigo em Inglês | MEDLINE | ID: mdl-31561904

RESUMO

The widespread presence of electromagnetic sources in daily life has initiated several studies on the effects of radiofrequency and power frequency fields. Only few investigations on the genotoxic effects of exposure to intermediate frequency magnetic fields (IF-MF) have been done so far. Therefore, the aim of this study was to evaluate possible genotoxic effects of exposure to 123.90 kHz and 250.80 kHz IF-MF on canine and human blood. Blood was exposed to IF-MF at 630 A/m (0.79 mT) and 80 A/m (0.10 m T) with exposure durations of 1-5 h (hourly), 20 and 24 h. Cylindrically divided Petri dish system was developed for in vitro exposures where different induced current could be achieved in the samples at the same magnetic flux density level. For the assessment of genotoxicity the alkaline comet assay was applied. We detected a statistically significant increase in DNA damage only following 20 h exposure to IF-MF.


Assuntos
Ensaio Cometa , Dano ao DNA , Leucócitos/efeitos da radiação , Campos Magnéticos/efeitos adversos , Adulto , Animais , Técnicas de Cultura de Células/instrumentação , Células Cultivadas , DNA/sangue , DNA/efeitos da radiação , Cães , Relação Dose-Resposta à Radiação , Campos Eletromagnéticos , Desenho de Equipamento , Feminino , Humanos , Leucócitos/química , Magnetismo/instrumentação , Masculino , Pessoa de Meia-Idade
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