The Role of Positive and Negative Affect in Illicit Substance Use and Alcohol Use: An Ecological Momentary Assessment Study.

BACKGROUND: Theories suggest that experiences of negative and positive affect are important precursors to alcohol and illicit substance use. Research utilizing ecological momentary assessments (EMA) has generally supported the relation between momentary experiences of positive affect, but not negative affect, and subsequent substance use. Unfortunately, most of these studies have focused on alcohol use and not other substance use. The goal of this paper was to further explore the relation between momentary affect and use of both alcohol and illicit substances within a population of individuals with a history of substance use. Additionally, this study aimed to understand whether the relations between affect and substance use would vary depending on the timing of EMA assessments of affect prior to substance use. METHOD: Participants with a history of heavy substance use (N = 59) completed EMA's measuring affect and substance use using random prompts 4 times a day for 14 days. RESULTS: We found that positive affect was significantly related to later engagement in drinking, illicit substance use, and marijuana use. Moreover, timing of the affect was important. When affect was assessed in the last hour prior to substance use, relative to 7 hours prior, the relation between positive affect and illicit substance use was stronger. Negative affect was related to a lower likelihood of subsequent marijuana use, but more so when it was measured a few hours versus several hours before the use. CONCLUSION: This study further supported the relation between positive affect and both alcohol and illicit substance use.

Eyes of the beholders: Multi-method relationships between internalizing and externalizing symptom dimensions and aggression risk.

Although aggression occurs across a range of disorders, associations between dimensions of psychopathology and self- and other-directed aggression are not well understood. Investigating associations between psychopathology dimensions and aggression helps further understanding about the etiology of aggression, and ultimately, can inform intervention and prevention strategies. This study adopted a multi-method approach to examine associations between internalizing and externalizing dimensions of psychopathology and self- and other-directed aggression as a function of reporter (participant and informant) and modality of aggression measurement (subjective and objective). Participants were an unselected sample of 151 racially diverse adults recruited from the community. Dimensions of psychopathology were assessed using interview and questionnaire reports from participants and collateral informants, and forms of aggression were measured via subjective reports and an objective, laboratory aggression paradigm. Analyses of participant-reported psychological symptom data consistently linked externalizing symptoms to other-directed aggression, and internalizing symptoms to self-directed aggression. Results across informant and participant reporters replicated prior findings showing a significant interaction between internalizing and externalizing dimensions in predicting intimate partner violence. Most other effects in informant models were nonsignificant. The findings uncover consistency in and replicability of relationships between dimensions of psychopathology and certain manifestations of aggression and highlight the importance of examining multiple forms of aggression in etiological research. Examining aggression through a transdiagnostic lens can help us better understand and intervene upon processes implicated in devasting forms of self- and other-directed aggression.

Everyday Sexual and Gender Minority Stress and Health: A Systematic Review of Experience Sampling Studies.

Sexual and gender minority stress is associated with negative physical and mental health outcomes, such as hypertension and depression. Expanding on previous reviews of the literature on cross-sectional and long-term prospective associations between sexual and gender minority stress and health outcomes, the current systematic review synthesizes the evidence on how everyday sexual and gender minority stress relates to momentary changes in health. The findings of 53 experience sampling studies published between 2007 and 2022 suggest that daily and momentary within-persons fluctuations in minority stressors are associated with cognitive-emotional (e.g., affect, suicidality), behavioral (e.g., substance use), social (e.g., relationship satisfaction), and physical health outcomes (e.g., somatic symptoms). These findings suggest that sexual and gender minority stress is a dynamic process that can vary within individuals over time and significantly impact everyday mental and physical health. We discuss the implications of these findings for minority stress theory, LGBTQ+ health research, LGBTQ+ affirming therapy, and prevention initiatives. The current experience sampling literature is limited by a lack of attention to gender minority stress and a focus on a limited range of health outcomes. Methodological and theoretical considerations for future experience sampling research are discussed in light of these limitations.

Appetitive and Aversive Motivation in Dysregulated Behaviors: A Meta-Analysis.

Appetitive and aversive motivation are prominent in theories of dysregulated behaviors. The authors conducted a meta-analysis of the association between individual differences in appetitive and aversive motivation and several dysregulated behaviors (i.e., alcohol use, marijuana use, tobacco use, binge eating, aggression, gambling, and nonsuicidal self-injury). Alcohol use (r = .17, k = 141), marijuana use (r = .13, k = 23), aggression (r = .22, k = 52), and gambling (r = .08, k = 55) were all significantly positively related to appetitive motivation. Binge eating (r = .28, k = 34) and self-injury (r = .17, k = 10) were significantly positively related to aversive motivation. Effect sizes were similar to the median effect size in personality research. Together, these results provide some evidence that some dysregulated behaviors are more correlated with approach motivation, whereas others are more correlated with aversive motivation, which may indicate distinct etiological pathways.

Social anxiety and alcohol consumption: The role of social context.

Research has identified social anxiety as a risk factor for the development of alcohol use disorder. However, studies have produced equivocal findings regarding the relationship between social anxiety and drinking behaviors in authentic drinking environments. This study examined how social-contextual features of real-world drinking contexts might influence the relationship between social anxiety and alcohol consumption in everyday settings. At an initial laboratory visit, heavy social drinkers (N = 48) completed the Liebowitz Social Anxiety Scale. Participants were then outfitted with a transdermal alcohol monitor individually-calibrated for each participant via laboratory alcohol-administration. Over the next seven days, participants wore this transdermal alcohol monitor and responded to random survey prompts (6x/day), during which they provided photographs of their surroundings. Participants then reported on their levels of social familiarity with individuals visible in photographs. Multilevel models indicated a significant interaction between social anxiety and social familiarity in predicting drinking, b = -0.004, p =.003 Specifically, among participants higher in social anxiety, drinking increased as social familiarity decreased b = -0.152, p <.001, whereas among those lower in social anxiety, this relationship was non-significant, b = 0.007, p =.867. Considered alongside prior research, findings suggest that the presence of strangers within a given environment may play a role in the drinking behavior of socially anxious individuals.

The downside of being openminded: The positive relation between openness to experience and nonsuicidal self-injury.

BACKGROUND: Sensation seeking and openness are two distinct, but related, individual differences that lead individuals to seek out intense sensations. As a result, these traits may also predispose individuals toward engaging in non-suicidal self-injury (NSSI); however, to date, no models have examined the relation between openness and NSSI after accounting for the influence of sensation. METHOD: The goals of this study were to (1) examine the relation between openness and NSSI while accounting for sensation seeking in a sample of racially diverse undergraduates (N = 340) and (2) conduct a meta-analysis of the existing research on the association between NSSI and openness. RESULTS: A negative binomial regression model demonstrated a significant positive association between NSSI and openness when accounting for sensation seeking; however, NSSI was not significantly related to sensation seeking. Moreover, multivariate meta-analysis with robust variance revealed a small, but significant, association between NSSI and openness across 15 studies. CONCLUSION: Together, these results suggest a positive association between openness and NSSI, highlighting an area for future research in what role openness to experience might play in the development of NSSI.

Dyadic effects of minority stress and problematic alcohol use on sexual intimate partner violence in same sex couples.

Little is known about the factors that facilitate the perpetration of sexual violence within the context of same-sex romantic relationships (sexual intimate partner violence perpetration [S-IPV]). The present study sought to identify the effects of external and internal minority stress and problematic drinking on perpetration of S-IPV within a dyadic framework. A community-based sample of 137 sexual and gender minority (SGM) couples (N = 274; 59 male assigned at birth and 78 female assigned at birth couples) completed self-report surveys about minority stressors, alcohol use, and S-IPV perpetration. Multilevel logistic regression analyses were conducted within an actor-partner interdependence framework. This approach accounted for both actor effects (e.g., how much one's S-IPV perpetration is predicted by their own risk factors) and partner effects (e.g., how much one's S-IPV perpetration is influenced by their partner's risk factors). Both Actor external minority stress and internal minority stress were positively associated with Actor S-IPV perpetration. Actor problematic drinking was not associated with Actor S-IPV perpetration; however, Partner problematic drinking was positively associated with Actor S-IPV perpetration. Observed effects were robust above the addition of other risk factors. This research innovatively extricates S-IPV perpetration from other forms of IPV and indicates that Actor minority stress and Partner problematic drinking increase S-IPV likelihood. Results serve as a starting point for development of etiological models to inform the design of culturally-informed interventions to reduce S-IPV among SGM couples.

Threat effects on attention networks in individuals with a history of externalizing behaviors.

Research identifying the biobehavioral processes that link threat exposure to cognitive alterations can inform treatments designed to reduce perpetration of stress-induced aggression. The present study attempted to specify the effects of relatively predictable versus unpredictable threat on two attention networks, attentional alerting and executive control. In a sample of adults (n = 74, 35 % identifying as women, Mage = 32.85) with high rates of externalizing behaviors (e.g., substance use, criminal/legal system involvement, aggressivity), we measured event-related brain activity during an attention network test that manipulated cognitive systems activation under relatively unpredictable and predictable threat conditions. Results showed that threat exposure alters attentional alerting and executive control. The predictable threat condition, relative to unpredictable threat, increased visual alerting (N1 amplitude to alert vs. no alert cue conditions) and decreased attention to the task (P3 amplitude to subsequent task-relevant flankers, but these effects did not survive adjusting for multiple tests. In contrast, overall threat and unpredictable threat conditions were associated with faster response time to alert cue (versus no cue) and poorer conflict processing, operationalized as flanker N2 reductions and slower response time to incongruent (versus congruent) flanker trials. These results expand what is known about threat-related modulation of cognition in a sample of individuals with histories of externalizing behaviors.

Impulsivity and Perpetration of Intimate Partner Aggression: The Moderating Effects of Negative Affective State and Alcohol.

Background: The goal of this study was to test the interactive effects of negative urgency, state negative affect, and alcohol intoxication on intimate partner aggression (IPA) perpetration. Methods: Heavy drinkers who recently perpetrated IPA completed self-report measures of impulsivity, were administered an alcohol or control beverage, and completed a laboratory aggression task. State negative affect was assessed unobtrusively via the Facial Action Coding System. Results: Consistent with our prediction, negative urgency was significantly and positively related to IPA when state negative affect was also high, but this relation was not significant when state negative affect was low. Conclusions: These results have implications for understanding the role of negative affect and impulsivity in IPA perpetration and for understanding trait models of impulsivity in general.

Unpacking the Construct of Dysregulated Behaviors Using Variable-Centered and Person-Centered Analytic Approaches.

Dysregulated behaviors (e.g., alcohol and drug use, aggression, self-harm, gambling, binge eating) occur frequently and can be severely costly to individuals and society. Yet, little is known about the construct of dysregulated behaviors, including (a) whether it is distinct from related constructs such as compulsive behaviors and sensation-seeking, (b) whether its components share common correlates (e.g., impulsigenic traits, reward sensitivity, and emotion dysregulation), and (c) identify and describe patterns of dysregulated behaviors. To address these gaps in the literature, this study used variable-centered and person-centered analyses in a racially diverse sample of undergraduates (n = 338). In support of evidence distinguishing dysregulated behaviors from related constructs, correlational analysis indicated that the associations with compulsive behaviors were small and nonsignificant. In terms of construct validity, we found relatively strong and consistent evidence for impulsigenic traits across dysregulated behaviors but relatively inconsistent evidence for associations with reward sensitivity and emotion dysregulation. Finally, person-centered analysis indicated the presence of three classes characterized by high dysregulated behavior, low dysregulated behavior, and aggressive self-harm behavior. The likelihood of being classified in these classes differed considerably based on impulsigenic traits and emotion dysregulation. These results may have implications for the classification and treatment of dysregulated behaviors. Taken together, this study advances our understanding of dysregulated behaviors and sets the stage for further theory development and hypothesis testing regarding the onset, maintenance, and treatment of dysregulated behaviors.Supplemental data for this article is available online at https://doi.org/10.1080/10826084.2022.2026966 .

Different Ways to Drown Out the Pain: A Meta-Analysis of the Association Between Nonsuicidal Self-Injury and Alcohol Use.

OBJECTIVE: There is a significant overlap in the motivations for nonsuicidal self-injury (NSSI) and alcohol use. Moreover, several theories would predict that more frequent alcohol use is likely associated with more NSSI engagement. Still, the size and direction of this association has not been well documented in the literature. METHOD: To address this gap, the goal of this article was to conduct a meta-analysis of the relation between alcohol use and NSSI. RESULTS: Across 57 samples and 141,669 participants, we found that there was a significant positive association between NSSI and alcohol use, odds ratio = 1.78, 95% confidence interval [1.53, 2.07], k = 64, m = 52. Moderator analyses found that this effect was stronger for younger samples and samples with more severe alcohol use problems. CONCLUSIONS: These results help establish a link between NSSI and alcohol use. Implications and future directions for NSSI research and intervention are discussed.HighlightsThere are several reasons to think that NSSI and alcohol use are linked.No reviews or meta-analyses have been conducted.We found a significant and small effect linking greater NSSI with greater alcohol use.

Associations Between Psychopathic Traits and Laboratory-Based Aggression: Moderating Effects of Provocation and Distraction.

There are two distinct combinations of psychopathic traits (primary and secondary) that have been proposed to be a function of unique cognitive-affective deficits. This study sought to use theories of psychopathy to understand the factors that exacerbate (i.e., provocation) and attenuate (i.e., distraction) aggression in individuals high in psychopathic traits in a controlled laboratory task. Male undergraduates, who scored across the range of primary and secondary psychopathic traits, completed the Taylor Aggression Paradigm (TAP; Taylor, 1967) under conditions of low and high provocation. Participants were also randomly assigned to either a distraction condition, in which they completed a distracting concurrent task, or a control condition, in which no such task was completed. Inconsistent with our prediction, results showed that regardless of condition, primary psychopathic traits were positively related to laboratory aggression. Consistent with our hypothesis, a positive association between secondary psychopathic traits and laboratory physical aggression was observed following high provocation among nondistracted participants; this association was significantly reduced among distracted participants. These results clarify the factors that contribute to aggression for individuals high in psychopathic traits and may provide directions for future intervention development.

From alcohol to aggression: Examining the structure and nomological network of dysregulated behaviors in a trauma-exposed community sample.

OBJECTIVE: A large body of research has shown that alcohol use, drug use, aggression, and self-harm often co-occur within the same individuals, suggesting the possibility of shared etiologies. Research has yet to determine the factor structure of these dysregulated behaviors. METHODS: Participants (Mage = 40.33; 74% women) completed self-report and interview-based measures of dysregulated behaviors (alcohol use, drug use, aggression, and self-harm), emotion dysregulation, maladaptive personality traits, and symptoms of DSM disorders (e.g., borderline personality disorder [BPD], depression). RESULTS: Results showed support for a bifactor model (i.e., all indicators load on a common dysregulated behavior factor and on unique alcohol, drug, aggression, and self-harm factors), which provided a better fit to the data than other models. In line with our hypotheses, the general dysregulated behavior factor was positively associated with emotion regulation difficulties, negative affect, and BPD symptoms. CONCLUSIONS: These results have implications for several areas of psychopathology and intervention research.

Craving and substance use: Examining psychophysiological and behavioral moderators.

Theories of substance use have emphasized the role of craving and inhibitory control in continued use, yet few studies have examined the interplay between momentary craving and inhibitory control in predicting illicit drug use in everyday life. The primary goal of this study was to examine whether individual differences in inhibitory control, indexed by laboratory-assessed electrophysiology and behavior, moderate the relation between momentary craving and alcohol and drug use assessed outside the lab using a smartphone. A secondary goal was to examine the extent of coherence in the results across different ERP components (e.g., no-go P3, ERN) purported to assess inhibitory control. Participants were current illicit drug users, who completed a flanker task that also contained go/no-go trials, and participated in two weeks of ambulatory assessments of their drug and alcohol craving and use. The results showed that craving a few hours before was related to subsequent drug and alcohol use; however, traditional measures of inhibitory control (e.g., go/no-go P3) did not moderate these effects as expected for illicit drug use. For alcohol use, individuals with less post-error slowing had a stronger relation between craving and alcohol use than those higher in post-error slowing. These results highlight that different cognitive processes are assessed by electrophysiological and behavioral measures of inhibitory control and may play different roles in drug and alcohol use and craving.

Facets of externalizing psychopathology in relation to inhibitory control and error processing.

A prominent characteristic of externalizing psychopathology is the inability to suppress or modulate behavioral responses and impulses. These tendencies have been associated with cognitive indicators of inhibitory control (P3) and error processing (error-related negativity [ERN] and positivity [Pe]). However, the extent to which these trait-like components are characteristic of specific manifestations, or externalizing proneness more generally, remains unclear. Our study aimed to further contextualize externalizing behaviors by examining associations between distinct facets of externalizing symptoms and relevant behavioral phenotypes (substance use, aggression, pathological personality and internalizing symptoms) as well as electrophysiological and behavioral indices of inhibitory control (congruence and no-go P3, flanker interference, commission errors) and error processing (ERN and Pe, post-error slowing). Using a sample of community and jail dwelling offenders (N = 497), we used Confirmatory Factor Analyses to estimate a general externalizing factor (EXT), representing shared variance, and latent factors representing symptoms related to callous-aggression (CAL; conduct disorder and antisocial personality disorder) and alcohol and drug dependence (AD and DD). Additionally, a subset of participants (N = 89) had their brain activity recorded during a flanker task. Factor analyses supported general EXT and CAL factors; however, unique AD/DD overlapped highly with shared EXT, suggesting that DSM substance use symptoms in our study reflect more general problems with disconstraint/impulsivity rather than variance specific to substances. The general EXT was marked by behavioral correlates of impulsivity and negative affect, and laboratory task deficits in error monitoring, but with greater differential processing of inhibitory cues. The CAL specific factor was associated with affective shallowness phenotype, and, interestingly, laboratory measures of enhanced processing of inhibitory cues and error adjustment. This research has implications for understanding neurocognitive processes associated with distinct manifestations of disordered behavioral inhibition.

The "Why" of Drinking Matters: A Meta-Analysis of the Association Between Drinking Motives and Drinking Outcomes.

BACKGROUND: Knowledge of how drinking motives are differentially associated with alcohol use (e.g., frequency, quantity) and drinking problems is critical in understanding risky drinking and the development of alcohol use disorder. The purpose of this paper was to use meta-analytic techniques to answer 2 overarching questions: (a) Which types of drinking motives (i.e., enhancement, coping, social, conformity) are most strongly associated with alcohol use and drinking problems? and (b) What are the most likely mechanisms (alcohol use or drinking problems) through which motives may be indirectly associated with outcomes? METHOD: A comprehensive literature search identified 229 studies that met inclusion criteria (254 samples; N = 130,705) with a subset containing longitudinal data (k = 5; N = 6283). Data were analyzed using 2-stage meta-analytic structural equation modeling. RESULTS: Results showed that both enhancement and coping motives were the strongest predictors of drinking problems, but only enhancement motives were the strongest predictor of alcohol use. Enhancement and social motives were indirectly associated with alcohol use through drinking problems and with drinking problems through alcohol use, whereas coping motives were only indirectly associated with alcohol use through drinking problems, although the results differed for cross-sectional and longitudinal data. CONCLUSION: Overall, findings from this meta-analysis provide evidence that drinking motives differentially predict alcohol use outcomes through unique direct and indirect pathways.

Toward a unifying theory of dysregulated behaviors.

Dysregulated behaviors, defined as active behaviors that have short-term benefits but cause serious recurrent long-term distress or impairment to the individual and/or those around them, include behaviors such as suicidal and nonsuicidal self-injury, aggression, and substance use. These behaviors are common and costly to the individual, their friends and family, and society. Despite similar etiological models and interventions, dysregulated behaviors have largely been studied in isolation from one another. The goals of this paper were to a) define dysregulated behaviors as a coherent class of behaviors, b) review the prevalence and consequences of dysregulated behaviors, c) outline how dysregulated behaviors fit into current models of psychopathology, and d) describe the key questions to be addressed by future research in this area. It is argued that integrating across theories of discrete dysregulated behaviors can help provide aid in the development of etiological models, which in turn can improve prevention and intervention for dysregulated behaviors.

Alcohol-related relationship dissatisfaction: A putative mechanism for intimate partner aggression.

Decades of research has identified alcohol use as a contributing cause of intimate partner aggression (IPA) perpetration; however, there have been fewer studies that seek to identify mediators of the relation between alcohol use and IPA perpetration. Building on research showing a positive association between problematic drinking and relationship dissatisfaction and relationship dissatisfaction and IPA, we examined whether relationship dissatisfaction accounted for the relation between problematic drinking and IPA perpetration in couples using statistical modeling that accounted for the interdependence between partners. Our results showed that (a) actor problematic drinking was related to actor psychological and physical IPA perpetration and that this relation was partially explained by actor relationship dissatisfaction, (b) partner problematic drinking was related to actor physical and psychological IPA perpetration and that this relation was partially explained by actor relationship dissatisfaction, and (c) partner problematic drinking was related to actor psychological IPA perpetration and that this relation was partially explained by partner relationship dissatisfaction. Together, our results highlight that when partner interdependence is considered, relationship dissatisfaction could be a potential mechanism of the alcohol-IPA association and provide some evidence for different pathways for psychological and physical aggression. (PsycInfo Database Record (c) 2020 APA, all rights reserved).

The Association Between Negative and Positive Affect and Alcohol Use: An Ambulatory Study.

OBJECTIVE: Negative and positive affect are proposed to play a crucial role in alcohol use and the development of alcohol use disorder. Results from ambulatory studies that measure momentary affect and subsequent alcohol use have been mixed, particularly regarding negative affect. We attempted to identify within-person moderators (i.e., time between assessments, prior blood alcohol content) that might explain mixed results. METHOD: We examined the association between self-reported affect and an objective measure of alcohol consumption (measured via a transdermal ankle bracelet) in a sample of heavy social drinkers across 7 days of ambulatory assessment. RESULTS: Our results showed that negative affect was negatively related to later drinking, whereas positive affect was positively related to later drinking. The results showed that these effects were stronger for amount consumed when affect was assessed closer rather than farther in time. CONCLUSIONS: These findings are important for understanding affect as an antecedent to alcohol use, which may ultimately have implications for the development of alcohol use disorder.

A meta-analytic review of laboratory studies testing the alcohol stress response dampening hypothesis.

Decades of research have tested the hypothesis that alcohol consumption buffers against the effects of stress. Despite this large body of literature, the evidence from carefully controlled laboratory studies in which alcohol is administered and negative affect is measured in response to a stressor is mixed. The goal of the current meta-analysis was to quantitatively summarize laboratory studies of alcohol's stress response dampening effects and test theoretical and methodological factors that explain variation in effect sizes across studies. A literature search identified 52 studies that administered alcohol and measured negative affect, as defined by self-report and/or psychophysiological response to a stressor. The results showed post-stressor negative affect was significantly lower in the alcohol condition compared to the control conditions (placebo and control), d = -.38, 95% CI [-.56, -.21], k = 130, m = 50. For changes in pre-to-post stressor affect, there was evidence of a small, but not significant, difference between the conditions such that negative affect increased slightly less in the alcohol condition, d = .49, 95% CI [.22, .77], k = 54, m = 27, compared to the control conditions, d = .60, 95% CI [.39, .80], k = 65, m = 26. Moderator analyses did not yield significant results but highlighted some areas for further research. Rather than providing definitive results on the topic of stress response dampening, this meta-analysis indicates several opportunities for refinement of method and theory to continue to improve the science in this area of research. (PsycINFO Database Record (c) 2019 APA, all rights reserved).