Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 5 de 5
Filtrar
Mais filtros










Base de dados
Intervalo de ano de publicação
1.
BMC Musculoskelet Disord ; 15: 292, 2014 Sep 03.
Artigo em Inglês | MEDLINE | ID: mdl-25186007

RESUMO

BACKGROUND: Due to difficulties in performing direct measurements as an exposure assessment technique, evidence supporting an association between physical exposures such as neck and shoulder muscle activities and postures and musculoskeletal disorders during computer use is limited. Alternative exposure assessment techniques are needed. METHODS: We predicted the median and range of amplitude (90th-10th percentiles) of trapezius muscle activity and the median and range of motion (90th-10th percentiles) of shoulder, head, neck, and torso postures based on two sets of parameters: the distribution of keyboard/mouse/idle activities only ("task-based" predictions), and a comprehensive set of task, questionnaire, workstation, and anthropometric parameters ("expanded model" predictions). We compared the task-based and expanded model predictions based on R2 values, root mean squared (RMS) errors, and relative RMS errors calculated compared to direct measurements. RESULTS: The expanded model predictions of the median and range of amplitude of trapezius muscle activity had consistently better R2 values (range 0.40-0.55 compared to 0.00-0.06), RMS errors (range 2-3%MVC compared to 3-4%MVC), and relative RMS errors (range 10-14%MVC compared to 16-19%MVC) than the task-based predictions. The expanded model predictions of the median and range of amplitude of postures also had consistently better R2 values (range 0.22-0.58 compared to 0.00-0.35), RMS errors (range 2-14 degrees compared to 3-22 degrees), and relative RMS errors (range 9-21 degrees compared to 13-42 degrees) than the task-based predictions. CONCLUSIONS: The variation in physical exposures across users performing the same task is large, especially in comparison to the variation across tasks. Thus, expanded model predictions of physical exposures during computer use should be used rather than task-based predictions to improve exposure assessment for future epidemiological studies. Clinically, this finding also indicates that computer users will have differences in their physical exposures even when performing the same tasks.


Assuntos
Computadores/estatística & dados numéricos , Modelos Biológicos , Postura/fisiologia , Amplitude de Movimento Articular/fisiologia , Músculos Superficiais do Dorso/fisiologia , Análise e Desempenho de Tarefas , Feminino , Previsões , Cabeça/fisiologia , Humanos , Masculino , Pescoço/fisiologia , Ombro/fisiologia , Tronco/fisiologia
2.
Am J Ind Med ; 56(10): 1190-200, 2013 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-23818000

RESUMO

BACKGROUND: Because of reported associations of psychosocial factors and computer related musculoskeletal symptoms, we investigated the effects of a workplace psychosocial factor, reward, in the presence of over-commitment, on trapezius muscle activity and shoulder, head, neck, and torso postures during computer use. METHODS: We measured 120 office workers across four groups (lowest/highest reward/over-commitment), performing their own computer work at their own workstations over a 2-hr period. RESULTS: Median trapezius muscle activity (P = 0.04) and median neck flexion (P = 0.03) were largest for participants reporting simultaneously low reward and high over-commitment. No differences were observed for other muscle activities or postures. CONCLUSIONS: These data suggest that the interaction of reward and over-commitment can affect upper extremity muscle activity and postures during computer use in the real work environment. This finding aligns with the hypothesized biomechanical pathway connecting workplace psychosocial factors and musculoskeletal symptoms of the neck and shoulder.


Assuntos
Computadores , Cervicalgia/fisiopatologia , Doenças Profissionais/fisiopatologia , Postura/fisiologia , Recompensa , Dor de Ombro/fisiopatologia , Músculos Superficiais do Dorso/fisiopatologia , Adulto , Fenômenos Biomecânicos , Eletromiografia , Feminino , Cabeça , Humanos , Masculino , Pessoa de Meia-Idade , Pescoço , Cervicalgia/psicologia , Doenças Profissionais/psicologia , Dor de Ombro/psicologia , Tronco , Carga de Trabalho/psicologia , Local de Trabalho/psicologia , Adulto Jovem
3.
Scand J Work Environ Health ; 39(4): 379-89, 2013 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-23377125

RESUMO

OBJECTIVE: Office workers with high levels of overcommitment and low levels of reward are thought to be more prone to arm-wrist-hand symptoms, possibly through a higher internal physical exposure. The aim of this study was to examine the effects of high overcommitment and low reward on (i) forearm muscle activity, (ii) wrist posture and kinematics, and (iii) forces applied to computer input devices during computer work in an actual work setting. METHODS: We continuously measured wrist extensor muscle activity, wrist posture and kinematics, and forces applied to the keyboard and mouse for two hours during the daily work of 120 office workers with four different levels of overcommitment and reward (low-high, high-high, low-low, and high-low). RESULTS: Wrist velocities and accelerations in radial-ulnar direction were higher for workers with high compared to low overcommitment, while their wrist range of motion was similar, possibly indicating a higher work pace. Wrist extensor muscle activity and forces applied to the keyboard and mouse were not increased by high overcommitment and/or low reward. CONCLUSION: Overall, our findings provide little support for the proposed pathway of high overcommitment and low reward in the development of arm-wrist-hand symptoms through a higher internal physical exposure.


Assuntos
Braço/fisiologia , Computadores , Músculo Esquelético/fisiologia , Exposição Ocupacional , Postura , Humanos
4.
J Neurosci ; 33(3): 1241-58, 2013 Jan 16.
Artigo em Inglês | MEDLINE | ID: mdl-23325260

RESUMO

Appropriately targeted manipulation of endogenous neural stem progenitor (NSP) cells may contribute to therapies for trauma, stroke, and neurodegenerative disease. A prerequisite to such therapies is a better understanding of the mechanisms regulating adult NSP cells in vivo. Indirect data suggest that endogenous ciliary neurotrophic factor (CNTF) receptor signaling may inhibit neuronal differentiation of NSP cells. We challenged subventricular zone (SVZ) cells in vivo with low concentrations of CNTF to anatomically characterize cells containing functional CNTF receptors. We found that type B "stem" cells are highly responsive, whereas type C "transit-amplifying" cells and type A neuroblasts are remarkably unresponsive, as are GFAP(+) astrocytes found outside the SVZ. CNTF was identified in a subset of type B cells that label with acute BrdU administration. Disruption of in vivo CNTF receptor signaling in SVZ NSP cells, with a "floxed" CNTF receptor α (CNTFRα) mouse line and a gene construct driving Cre recombinase (Cre) expression in NSP cells, led to increases in SVZ-associated neuroblasts and new olfactory bulb neurons, as well as a neuron subtype-specific, adult-onset increase in olfactory bulb neuron populations. Adult-onset receptor disruption in SVZ NSP cells with a recombinant adeno-associated virus (AAV-Cre) also led to increased neurogenesis. However, the maintenance of type B cell populations was apparently unaffected by the receptor disruption. Together, the data suggest that endogenous CNTF receptor signaling in type B stem cells inhibits adult neurogenesis, and further suggest that the regulation may occur in a neuron subtype-specific manner.


Assuntos
Ventrículos Laterais/fisiologia , Neurogênese/fisiologia , Neurônios/fisiologia , Prosencéfalo/fisiologia , Receptor do Fator Neutrófico Ciliar/metabolismo , Células-Tronco Adultas/citologia , Células-Tronco Adultas/metabolismo , Animais , Fator Neurotrófico Ciliar/metabolismo , Ventrículos Laterais/citologia , Camundongos , Camundongos Transgênicos , Células-Tronco Neurais/citologia , Células-Tronco Neurais/metabolismo , Neurônios/citologia , Bulbo Olfatório/citologia , Bulbo Olfatório/fisiologia , Receptor do Fator Neutrófico Ciliar/genética , Transdução de Sinais/fisiologia
5.
J Occup Environ Hyg ; 9(12): 691-8, 2012.
Artigo em Inglês | MEDLINE | ID: mdl-23066993

RESUMO

Prediction models were developed based on keyboard and mouse use in combination with individual factors that could be used to predict median upper extremity muscle activities, postures, velocities, and accelerations experienced during computer use. In the laboratory, 25 participants performed five simulated computer trials with different amounts of keyboard and mouse use ranging from a highly keyboard-intensive trial to a highly mouse-intensive trial. During each trial, muscle activity and postures of the shoulder and wrist and velocities and accelerations of the wrists, along with percentage keyboard and mouse use, were measured. Four individual factors (hand length, shoulder width, age, and gender) were also measured on the day of data collection. Percentage keyboard and mouse use explained a large amount of the variability in wrist velocities and accelerations. Although hand length, shoulder width, and age were each significant predictors of at least one median muscle activity, posture, velocity, or acceleration exposure, these individual factors explained very little variability in addition to percentage keyboard and mouse use in any of the physical exposures investigated. The amounts of variability explained for models predicting median wrist velocities and accelerations ranged from 75 to 84% but were much lower for median muscle activities and postures (0-50%). RMS errors ranged between 8 to 13% of the range observed. While the predictions for wrist velocities and accelerations may be able to be used to improve exposure assessment for future epidemiologic studies, more research is needed to identify other factors that may improve the predictions for muscle activities and postures.


Assuntos
Computadores , Transtornos Traumáticos Cumulativos/epidemiologia , Modelos Teóricos , Doenças Musculoesqueléticas/epidemiologia , Exposição Ocupacional/análise , Postura , Previsões , Humanos , Ombro/fisiologia , Punho/fisiologia
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...