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1.
J Environ Manage ; 354: 120381, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-38359626

RESUMO

The results of a comparative study of two different technological solutions applicable to decentralised domestic wastewater treatment systems are presented. A hybrid reactor with activated sludge and mobile biofilm carriers moving in wastewater is one of them, and an innovative quasi-technical combination of a biological reactor with a sprinkled bed filled with sintered clay granules, followed in the process line by an innovative slope type filtration bed, is the other one. The study has shown a significant advantage of filter bed installations in functional quality, expressed in low values of indicators and pollutant concentrations. In the comparison of technological reliability and probability of exceeding the requirement values of BOD5 = 40 mg/L, Facility 1 achieved technological reliability of 70% and probability of exceeding was 23%. Technological reliability of Facility 2 in this component was 100% and P = 0%. Both facilities presented 100% technological reliability in the COD indicators, with zero probability of exceeding the required value of 150 mg/L. The reliability of TSS removal was similarly high in both facilities: 91% and 100%. The higher functional quality of Facility 2 was evident in TN and PO4-P parameters, where the period of its operation with exceeded values did not exceed 20% and 13%, respectively, with a low probability of exceeding the value of 18% and 2.5%, respectively. However, Facility 1 was unreliable in this regard in 90% and 84%, with a very high probability of exceeding the required values of these parameters: 88% and 72%. This facility does not meet the required criteria in this respect and may cause a risk to the aquatic environment if wastewater is discharged directly into open watercourses, or if it enters shallow groundwater. The use of a suitable, biologically active soil-plant receiver can eliminate this risk.


Assuntos
Poluentes Ambientais , Purificação da Água , Águas Residuárias , Eliminação de Resíduos Líquidos/métodos , Reprodutibilidade dos Testes , Reatores Biológicos , Esgotos , Purificação da Água/métodos , Biofilmes
2.
Cells ; 11(19)2022 09 27.
Artigo em Inglês | MEDLINE | ID: mdl-36230984

RESUMO

Nowadays, molecular research is essential for the better understanding of tumor cells' pathophysiology. The increasing number of neoplasms is taken under 'the molecular magnifying glass'; therefore, it is possible to discover the complex relationships between cytophysiology and tumor cells. Signal transducer and activator of transcription 3 (STAT3) belongs to the family of latent cytoplasmic transcription factors called STATs, which comprises seven members: STAT1, STAT2, STAT3, STAT4, STAT5A, STAT5B, and STAT6. Those proteins play important role in cytokine-activated gene expression by transducing signals from the cell membrane to the nucleus. Abnormal prolonged activation results in tumorigenesis, metastasis, cell proliferation, invasion, migration, and angiogenesis. Inhibition of this transcription factor inhibits the previously mentioned effects in cancer cells, whereas normal cells are not affected. Hence, STAT3 might be a viable target for cancer therapy.


Assuntos
Fator de Transcrição STAT3 , Neoplasias Urológicas , Citocinas/metabolismo , Humanos , Fator de Transcrição STAT3/metabolismo , Transdução de Sinais
3.
Sci Total Environ ; 718: 137371, 2020 May 20.
Artigo em Inglês | MEDLINE | ID: mdl-32092523

RESUMO

This paper reports a comparative study on kinetics of organic matter expressed as BOD5 and nitrogen removal in constructed wetlands operated in Poland. Analyzed data were collected at eight wetland systems, composed of subsurface flow beds: horizontal flow (HF) and vertical flow (VF), in different number and sequences. The analysis involved particularly mass removal rates (MRR) and first-order removal rate coefficients of BOD5 and total nitrogen (kA and kv for VF and HF filters, respectively, and k20 as a parameter averaged for a temperature of 20 °C). It was found that the higher the load of pollutants applied to the beds, the higher MRR values were obtained. The average k-rates in analyzed systems were mostly lower than those reported in the literature, especially in the case of total nitrogen. Its removal obtained in horizontal flow beds was kv = 0.002-0.042 d-1, while in vertical flow systems kA varied from 0.007 m d-1 to 0.0037 m d-1. According to data given by previous studies, first-order reaction rates for nitrogen removal varied in range from kv = 0.048 d-1 to kv = 0.19 d-1 and kA from 0.007 to 0.1 m d-1 in HF and VF beds, respectively. Regarding BOD5 shown in literature, removal rate kv for HF beds varied from 0.071 to 6.11 d-1, and kA for VF beds varied from 0.019 to 1.0 m d-1, while in this study lower k-rates were obtained: kv = 0.005-0.085 d-1 and kA = 0.015-0.130 m d-1. Relatively long monitoring period, for some of constructed wetland up to 16 years, resulted in good data set and enables creation of the graphs, which could be helpful in evaluation and designing of constructed wetlands for PE bigger than 50, in moderate climate conditions.

4.
Environ Technol ; 41(17): 2196-2209, 2020 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-30526391

RESUMO

The aim of the study was to evaluate the nitrogen removal and its effects on the plant's growth and leaves morphology. using two subsurface vertical flow (VF bed), with different depths (0.24 m2 × 0.70 m; 0.24 m2 × 0.35 m) and nitrogen load increments. The VF bed were planted with Vetiveria zizanioides, filled with light expanded clay aggregates (Leca®NR 10/20) and fed in parallel mode with synthetic wastewater. High ammonium nitrogen concentration ([NH4 +-N] from 68 ± 3 to 290 ± 8 mg L-1) was used without toxicity symptoms in plants, although the effects of ammonium nitrogen load were stopped the growth of the plants. Significant differences between ammonium nitrogen removed in each VF bed obtained for total nitrogen (TNinfl.) ≥ 27 ± 0.8 g m-2 d-1. The nitrification was contributed to ammonium nitrogen removal because was found higher values of nitrate and nitrite in the effluent. These values were more higher in VF bed 1 than in the VF bed 2, since ammonium nitrogen removal were also more higher in VF bed 1 than in the VF bed 2. Total nitrogen mass balance was carried out and the results show that the nitrification/denitrification process occurred with nitrogen plants uptake. It was observed that the VF bed depth has an influence on all nitrogen removal processes. As higher the depth root system it is seemed to favour the creation of zones with different oxidations conditions that allow the nitrogen compounds to be removed intensively.


Assuntos
Nitrogênio , Áreas Alagadas , Desnitrificação , Eliminação de Resíduos Líquidos , Águas Residuárias
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