Camouflage treatment of skeletal Class III malocclusion with conventional orthodontic therapy.

Nonextraction camouflage treatment along with Class III elastics was used to treat a 39-year-old woman with a skeletal Class III pattern and a low mandibular plane angle and short lower anterior facial height. The total active treatment time was 26 months. Her occlusion, smile esthetics, and soft tissue profile were significantly improved after treatment.

Self-perception of the facial profile: an aid in treatment planning for orthognathic surgery.

PURPOSE: To investigate the difference between the self-perception of the facial profile and analogous measurements of profile photographs in 2 age groups, adolescents and young adults, and adults. PATIENTS AND METHODS: A prototypical Caucasian profile was constructed for each gender by averaging the profiles of 28 subjects with normal occlusion. Each prototypical profile was manipulated by protruding and retruding the lips in 1-mm increments to construct a series of 13 silhouettes. Next, 85 laypeople were divided into 2 groups: adolescents and young adults (age, 15 to 25 years) and adults (age, 26 to 55 years). They were asked to complete a questionnaire that included choosing the facial profile in the constructed series they thought most resembled their own profile photograph. For each group, the difference between the chosen and actual profile was compared using a 1-sample t test. The differences between the 2 groups in identifying their own profile were compared using a 2-sample t test. RESULTS: The 2 groups were different in their ability to recognize their own profile (P = .040 for the upper lip and P = .006 for the lower lip). The adolescent and young adult group was most accurate, showing no significant difference from 0 for the chosen and actual profiles. However, the adult group was significantly different for both the upper (P = .040) and lower (P = .003) lips. CONCLUSIONS: From our study results, most laypeople aged 15 to 25 years could accurately evaluate the fullness of their own facial profile, although adults aged 26 to 55 years had more difficulty in this evaluation and tended to overestimate the protrusion of their lips.

High-risk human papillomavirus (HPV) screening and detection in healthy patient saliva samples: a pilot study.

BACKGROUND: The human papillomaviruses (HPV) are a large family of non-enveloped DNA viruses, mainly associated with cervical cancers. Recent epidemiologic evidence has suggested that HPV may be an independent risk factor for oropharyngeal cancers. Evidence now suggests HPV may modulate the malignancy process in some tobacco- and alcohol-induced oropharynx tumors, but might also be the primary oncogenic factor for inducing carcinogenesis among some non-smokers. More evidence, however, is needed regarding oral HPV prevalence among healthy adults to estimate risk. The goal of this study was to perform an HPV screening of normal healthy adults to assess oral HPV prevalence. METHODS: Healthy adult patients at a US dental school were selected to participate in this pilot study. DNA was isolated from saliva samples and screened for high-risk HPV strains HPV16 and HPV18 and further processed using qPCR for quantification and to confirm analytical sensitivity and specificity. RESULTS: Chi-square analysis revealed the patient sample was representative of the general clinic population with respect to gender, race and age (p < 0.05). Four patient samples were found to harbor HPV16 DNA, representing 2.6% of the total (n = 151). Three of the four HPV16-positive samples were from patients under 65 years of age and all four were female and Hispanic (non-White). No samples tested positive for HPV18. CONCLUSIONS: The successful recruitment and screening of healthy adult patients revealed HPV16, but not HPV18, was present in a small subset. These results provide new information about oral HPV status, which may help to contextualize results from other studies that demonstrate oral cancer rates have risen in the US among both females and minorities and in some geographic areas that are not solely explained by rates of tobacco and alcohol use. The results of this study may be of significant value to further our understanding of oral health and disease risk, as well as to help design future studies exploring the role of other factors that influence oral HPV exposure, as well as the short- and long-term consequences of oral HPV infection.