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Nutrients ; 10(5)2018 May 01.
Artigo em Inglês | MEDLINE | ID: mdl-29723971

RESUMO

Adult-type hypolactasia (ATH) is a clinical syndrome of primary lactase deficiency. A lactose-free diet is advisable to avoid the symptoms linked to the condition, but this potentially creates problems for optimal bone mineralization due to reduced calcium intake. To evaluate the effect of the lactose-free diet on the bone mineral status (BMS), we compared the phalangeal BMS of adolescents with ATH to that of peers on a normal diet. Also, we analyzed the correlations between BMS and dietary behavior, physical exercise, and calcium and vitamin D intake. A total of 102 cases and 102 healthy controls filled out a diet record and underwent phalangeal Quantitative Ultrasound (QUS). No difference in BMS was observed. The time spent on lactose-free diet (4.8 ± 3.1 years) was inversely correlated to the BMS. More than 98% of cases consumed lactose-free milk, but calcium and vitamin D intake were significantly lower. Calcium intake was correlated to physical exercise but not to BMS. Our results suggest that a lactose-free diet does not affect the phalangeal BMS of adolescents with primary lactase deficiency when their diet includes lactose-free cow’s milk. However, there is still a significantly lower calcium intake than in the population reference. The inverse correlation observed between the BMS and the time spent on a lactose-free diet suggests that a long-term follow-up is advisable.


Assuntos
Densidade Óssea , Dieta , Falanges dos Dedos da Mão/química , Lactase/deficiência , Intolerância à Lactose/dietoterapia , Lactose/administração & dosagem , Adolescente , Animais , Índice de Massa Corporal , Peso Corporal , Cálcio da Dieta/administração & dosagem , Erros Inatos do Metabolismo dos Carboidratos , Estudos de Casos e Controles , Registros de Dieta , Estudos de Avaliação como Assunto , Exercício Físico , Feminino , Falanges dos Dedos da Mão/diagnóstico por imagem , Comportamentos Relacionados com a Saúde , Humanos , Masculino , Leite/química , Estado Nutricional , Ultrassonografia , Vitamina D/administração & dosagem , Adulto Jovem
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